A method of examining a response from one or more pupils of an eye is described. The method includes providing a hand-held mobile device with a display, a built-in camera, and a light stimulus source, wherein the light stimulus source can emit light at various intensities; using the mobile device to locate the pupil; using the mobile device to determine a distance between the device and the pupil; applying an algorithm that calculates a specific or optimal light intensity based on the distance between the device and the eye and causes the light stimulus source to emit one or more flashes of light at the specific or optimal light intensity; using the built-in camera to record the response of the pupil to the one or more flashes of light; and displaying on the display the data representative of the response of the pupil to the one or more flashes of light.

A method for manufacturing an optical device, includes obtaining a plurality of test images in each of which spectral intensities of a first color component, a second color component and a third color component are separately changeable, changing the spectral intensity of the first color component in at least a first test image, changing the spectral intensity of the second color component in at least a second test image, obtaining a spectral intensity Rs of the first color component and a spectral intensity Gs of the second color component satisfying a particular test condition when a subject is looking at the first and second test images, and manufacturing the optical device including an optical element configured to adjust spectral intensities of the first color component and the second color component, in light transmitted through the optical element, based on the spectral intensities Rs and Gs.

A method of determining that an absence of suspicion of neurological injury is indicated in a subject is disclosed. The method involves prompting the subject to engage in three or more of the following neurological assessments: a) Reading Saccades, b) Near/far accommodation using Hart charts of different font sizes; c) Brock string, d) Maddox rod, e) closed-eye turns, f) Near Point of Convergence, and g) PERRLA with consensual reflex. The data from the neurological assessments is used to determine that an absence of suspicion of neurological injury is indicated in the subject.

The present invention provides a reading test to measure vision loss. In one embodiment, the vision loss is due to disease progression. The tests are useful in evaluating the effects of intervention in vision deterioration. The tests are non-invasive, simple, quick, sensitive, reproducible, and easy to administer. The tests measure the subject's reading speed and accuracy under defined conditions of illumination and contrast. The results of these tests may be used to determine if treatment of a disease should be initiated, terminated, altered, or remain unchanged.

Methods, apparatus, and systems for performing an ophthalmic diagnostic test are disclosed. In one aspect, a head-wearable device for administering an ophthalmic test to a subject can comprise a head-wearable frame for mounting the device onto the subject's head, and a light seal configured for coupling to the frame so as to isolate at least one eye of the subject from ambient light when the device is worn by the subject.

A measuring method for measuring sensitivity of eye around certain line of sight includes: showing image of predetermined pattern on a display screen showing in front of eyeball of subject by display device secured to head; showing fixation target focused on by subject, on display screen to make line of sight of subject; showing change region where predetermined pattern image is changed, at anisotropic area around intersection point or fixation target in screen is separated from intersection point and fixation target, intersection point wherein subject certain line of sight focuses on fixation target, crosses display screen; showing change region where predetermined image pattern is changed on display screen, wherein change region manner is continuously or intermittently brought close to or away from intersection point or fixation target in display screen; and determining range wherein subject senses change region by bringing it close or away from intersection point or fixation target.

A method and apparatus are provided for measuring a sensitivity level across a visual field of a subject defined by a set of locations. The method comprises: presenting a sequence of visual stimuli on a display, wherein each stimulus in the sequence has a respective intensity level and is positioned on the display to correspond to a respective location from the set of locations; obtaining from the subject, for each stimulus, a respective binary response indicating whether or not the stimulus was seen by the subject; and after receiving the response from the subject for a given stimulus in the sequence, using a statistical model to estimate, for each location in the set of locations, the sensitivity level at that location; wherein the statistical model incorporates information about correlations in responses between different locations from the set of locations and takes as input, the respective binary response, intensity level and location for multiple stimuli presented in said sequence up to and including the given stimulus.

A new ocular contact lens has been designed to increase the amount of light reaching the retina. The contact lens edge is chamfered to redirect and increase the light reaching the retina. A light source encircles and contacts the straight or curved chamfered edge. Additionally, a reflective cylinder and its top wall encircle the lens to block any loss of light. This distal edge of the contact lens may be rounded to increase the angle of retina visible. A new ocular imaging camera has a low-light camera subassembly with server, a photosensor next to low-light camera, a short cylindrical housing, a space between the camera subassembly and the housing, an internal program in server to detect good or poor image quality and an alarm for poor image quality, wherein an operator recaptures the image. A system has a highly efficient method to screen and diagnose a large number of patients using the new ocular contact lens and ocular imaging camera. The system receives and processes the photographs. The photographs are transmitted to eye care specialists' smart phone, tablet or virtual reality device for evaluation. As specified, the eye care specialist separates normal from abnormal, diagnoses the abnormality, and may even provide detailed information, such as the grade of the abnormality. The server receives this information and automatically generates the suitable report for the healthcare professional. The server also processes payment to the eye care specialist.

The present disclosure provides an improved method for photobleaching an eye of a subject. The disclosed method may be used in a number of psychophysical test methods, including, but not limited to, measurement of dark adaptation. The improved method for photobleaching involves at least one of the following improvements: (i) the use of a bleaching light emitting a particular wavelength of light or a tailored spectrum of wavelengths; (ii) restricting or otherwise spatially tailoring the region of the retina that is subject to photobleaching; and (iii) utilizing a bleaching light having an intensity that is at or below the intensity of ambient daylight. The present disclosure additionally provides a combination of a photobleaching light and an apparatus to administer a psychophysical test suitable for use in practicing the disclosed methods.

Embodiments of the invention are directed towards systems, methods and computer program products for providing improved eye tests. Such tests improve upon current eye tests, such as visual acuity tests, by incorporating virtual reality, software mediated guidance to the patient or practitioner such that more accurate results of the eye tests are obtained. Furthermore, through the use of one or more trained machine learning or predictive analytic systems, multiple signals obtained from sensors of a testing apparatus are evaluated to ensure that the eye test results are less error-prone and provide a more consistent evaluation of a user's vision status. As it will be appreciated, such error reduction and user guidance systems represent technological improvements in eye tests and utilize non-routine and non-conventional approaches to the improvement and reliability of eye tests.