A system is disclosed for capturing diagnostic eye information. The system includes at least one energy source for directing electromagnetic energy into an eye of a subject, a plurality of perception units, each perception unit being associated with an associated position in the visual field of the eye, and each perception unit being adapted to capture refractive information from the eye responsive to the electromagnetic energy, and a processing system for determining refractive error information associated with each position of each perception unit in the visual field of the eye, and for determining refractive error composite information regarding the eye responsive to the refractive error information associated with each perception unit and independent of a direction of gaze of the eye.

A method is disclosed for testing hearing in infants based on pupil dilation response. It does not require sedation or depend on subjective judgments of human testers. Pupil dilation response to sound is measured by presenting on a display a visually engaging video containing periodic changes; presenting sounds synchronized with the periodic changes of the video; recording images from a camera directed in front of the display, where the camera is sensitive to infrared wavelengths; processing the images to measure pupil sizes; and processing the measured pupil sizes to determine, statistically, the presence of a pupil dilation response to the sounds.

Electrode array for monitoring of physiological parameters and devices including or utilizing same, the electrode array including an active electrode configured to provide an electrical signal and at least two inactive electrodes configured to collect the electrical signal transferred from the active electrode, wherein each of the at least two inactive electrodes are positioned at a different predetermined distance from the active electrode.

A method for generating an indicator or biomarker of colour perception in a mammalian subject, where the method may include submitting the mammalian subject to a multicoloured dynamic stimulus comprising displaying, on a display device. The method may include controlling a change over time of at least one of the two colours of the multicolour pattern when displaying the dynamic multicolour stimulus, to vary the displayed luminance of this colour (usually several times). The method may include acquiring, by using an image acquisition device, an oscillatory response of a pupil of the mammalian subject. The method may include generating, from the acquired response, a signal representative of the power of the pupil's oscillatory response as a function of the change over time of at least one of the two colours when displaying the dynamic multicoloured stimulus.

A method of predicting the outcome of a hospitalized acute brain injury patient is provided. The method includes using a pupilometer to take paired pupillary measurements of a left and right eye of the patient; using the pupilometer to determine NPI of the left eye and display it on a display of the pupillometer; using the pupillometer to determine NPI of the right eye and display it on the display of the pupillometer; calculating a differential between NPI of the left eye and NPI of the right eye and display said NPI differential on the display of the pupillometer; and predicting an unfavorable health or neurological outcome if the NPIs of the left and right eyes indicate normal pupillary responses for each eye but the NPI differential meets or exceeds a given threshold value.

Anatomically-constrained gaze estimation providing a point of reference (PoR) in a 3D field and/or 2D plane, based on 6 DOF head pose constrained by the eyeball center being fixed in a common 3D coordinate system.

Pupillometry systems for measuring pupillary characteristics of a patient are shown and described. The pupillometry systems include at least one camera, and a computer system in data communication with the at least one camera, the computer system having a processor and a non-transitory computer-readable storage medium. The non-transitory computer-readable storage medium includes computer-readable instructions for collecting and time stamping the image data, processing the raw image data in such a way as to bring the images into conformance with standardized image parameters, identifying and measuring the one or more pupils in the image data, processing the image data to produce measurement data of change in the one or more pupillary characteristics, calculating a standardized output of measurement data for the one or more pupillary characteristics, and providing a mechanism to share or store this information with other users via a computer network.

According to the present invention there is provided a computer implemented method for determining a representation which indicates the activity of a locus coeruleus system of a user, comprising the steps of, measuring the size of a pupil of a user; providing a representation the appearance of which is based on the measured size of the pupil. There is also provided a method for estimating the activity of a locus coeruleus system of a user. There is also provided assemblies which can be used to perform said afore-mentioned methods.

The invention is related to an eye tracking system for determining reference gaze data of a user in a scene exposing a pupil of the user. The eye tracking system comprising processing circuitry configured to obtain a first eye image comprising the pupil of the user, the first eye image being captured during a first time period; determine, based on the first eye image, a first pupil size; obtain a second eye image comprising the pupil of the user, the second eye image being captured during a second time period; determine, based on the second eye image, a second pupil size; obtain scene information of the scene exposing the pupil of the user, the scene information comprising at least the first luminance level, the second luminance level and spatial information of the second region during the second time period; determine a pupil size change between the first pupil size and the second pupil size, the pupil size change indicating that the user is looking at the second region; determine reference gaze data of the user during the second time period, if the pupil size change is larger than a pupil size change threshold. The invention further relates to a head-mounted device, a method, a computer program and a carrier.

A device for measuring eye movement in a human subject comprises a housing, at least one stimulator mounted to the housing, and a sensor. The at least one stimulator is configured to provide stimulus to one or both eyes of the subject. The sensor is configured to collect information related to movement of one or both eyes of the subject. The device also includes a user interface that is configured to control the at least one stimulator and display information collected by the camera.