A61B3/1225

Systems, Methods and Computer Program Products for Optimizing Optics of a Surgical Microscope Having an Integrated Imaging System
20230107680 · 2023-04-06 ·

A system for optimizing optics is provided. The system is configured to calibrate a position of a reference arm of an interferometric imaging system such that an image of a sample is visible when the sample is positioned at a working distance of an objective lens to provide an initial calibrated position. An image is obtained using the initial calibrated position. Image quality of the obtained image is assessed to determine if the obtained image is a valid image. A path length of the reference arm is adjusted if it is determined that the obtained image is not a valid image. A difference between the calibrated position of the reference arm and the adjusted position of the reference arm is calculated. System elements are adjusted based on the calculated difference such that the ample is visible when the sample is positioned at the working distance at the adjusted position.

MACHINE-LEARNING TECHNIQUES FOR PREDICTION OF FUTURE VISUAL ACUITY

Methods and systems disclosed herein relate generally to systems and methods for predicting a future visual acuity of a subject by using machine-learning models. An image of at least part of a retina of a subject can be processed by one or more first machine-learning models to detect a set of retina-related segments. Segment-specific metrics that characterize a retina-related segment of the set of retina-related segments can be generated. The segment-specific metrics can be processed by using a second machine-learning model to generate a result corresponding to a prediction corresponding to a future visual acuity of the subject.

Ophthalmic device
11617509 · 2023-04-04 · ·

An ophthalmic device including an illumination module which scans light across a region of the retina of an eye when the pupil is disposed at a focal point of the illumination module. The ophthalmic device further comprises components (2, 3-1, 4-1) for: aligning the pupil with the focal point; monitoring a position of the pupil relative to the focal point and maintaining the alignment based on the monitored position; aligning a scan location of the illumination module on the retina to a target scan location while the alignment of the pupil with the focal point is being maintained, wherein the illumination module performs a scan at the target scan location. The ophthalmic device further maintains the scan location at the target scan location while the alignment of the pupil with the focal point is being maintained, using scan location correction information based on retinal feature information.

REAL-TIME IR FUNDUS IMAGE TRACKING IN THE PRESENCE OF ARTIFACTS USING A REFERENCE LANDMARK
20230143051 · 2023-05-11 ·

A system and method for ophthalmic motion tracking. An anchor point and multiple auxiliary points are selected from a reference image. Individual live images in a series of images are then searched for matches of the anchor point and auxiliary point. First, the anchor point is found, and then searches for individual auxiliary points is limited to a search window defined by the known distance and/or orientation of the sought auxiliary point relative to the anchor point.

OPTICAL SYSTEM AND OPERATING METHOD THEREOF
20230148861 · 2023-05-18 ·

An optical system and an operating method thereof are disclosed. The optical system includes a light source device, a gaze module and a fundus detection device. The light source device includes a light source module, a light intensity modulation module and a lens module. The light source module is used to emit a therapy light to an eye. The light intensity modulation module is used to modulate an intensity of the therapy light. The lens module is used to control a depth of the therapy light. The gaze module is used to be gazed by the eye to fix a fundus of the eye. The fundus detection device and the light source device are integrated to detect the fundus to obtain a fundus image.

Ophthalmic imaging system

An ophthalmic imaging system including an ocular lens and an optical coherence tomography (OCT) imaging module is provided. The OCT imaging module is able to image both retina and anterior segment of eyes by switching a lens group into and out of the OCT light path. The OCT imaging module includes a retina imaging mode and an anterior segment imaging mode. In the retina imaging mode, there exists an intermediate image plane located between the ocular lens and the OCT imaging module. From the retina imaging mode, anterior segment imaging is achieved by inserting a switching lens group into the optical path inside the OCT imaging module or replacing the whole OCT imaging module of the retina mode, wherein, after the insertion, there exist a new intermediate image plane located inside the OCT imaging module and a conjugate of the entrance pupil of the OCT imaging module located between the ocular lens and the OCT imaging module.

System and method for multi-scale retinal imaging
11684257 · 2023-06-27 · ·

The multi-scale scanning imaging system (200) of the retina comprises according to an example a lighting and detection module (210) configured for emitting a lighting beam and for detecting a beam reemitted by the retina, a first scanning module (231) of the lighting beam and the reemitted beam, a first optical path, referred to as a “wide field” path, and a second optical path, referred to as a “small field” path, for focusing the lighting beam on the retina and for receiving the beam reemitted by the retina. The “wide field” path comprises a first optical system (205, 201) configured to conjugate a plane located near a plane of rotation of the scanning module and the plane (17) of the entrance pupil of the eye (10). The “small field” path comprises a wavefront correction device (250), a second optical system (257, 256, 253) configured to conjugate a plane located near a plane of rotation of the at least one first scanning module and the effective surface of the wavefront correction device, a third optical system, comprising at least part of the first optical system, configured to conjugate said effective surface (251) of the correction device and the plane of the entrance pupil of the eye. The multi-scale scanning imaging system further comprises a first optical deflection element (241) configured to send the beam reemitted by the retina on one and/or the other of the first and second imaging paths and intended to be positioned on the first imaging path, between the common part (201, 205) of the first and third optical systems and the scanning module (210), and on the second imaging path, between the common part of the first and third optical systems and the wavefront correction device.

Scan pattern and signal processing for optical coherence tomography

An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.

OCT MOTION CONTRAST ACQUISITION METHOD AND OPTICAL COHERENCE TOMOGRAPHY DEVICE
20170360294 · 2017-12-21 · ·

An OCT motion contrast data acquisition method using an optical coherence tomography device includes: controlling an optical scanner for scanning measurement light on a test subject; performing a first scanning control for obtaining a first OCT signal group including at least four temporally different OCT signals at a same scanning position; performing a second scanning control for obtaining a second OCT signal group including at least four temporally different OCT signals at the same scanning position; obtaining first motion contrast data based on the first OCT signal group obtained in the first scanning control; obtaining second motion contrast data based on the second OCT signal group obtained in the second scanning control; and obtaining third motion contrast data based on the first motion contrast data and the second motion contrast data.

ILLUMINATION APPARATUS, ILLUMINATION METHOD, ILLUMINATION SYSTEM AND METHOD FOR OPERATING AN ILLUMINATION SYSTEM
20230190088 · 2023-06-22 ·

An illumination apparatus for illuminating an examination object, in particular for illuminating a fundus section of a patient's eye, includes at least one light source which emits light onto a micromirror actuator, which is controllable by a control device for the purpose of preshaping the wavefront reflected by the micromirror actuator, and at least one light guide configured to guide the reflected light of the light source that has been preshaped by the micromirror actuator to an examination object. The light guide includes a first end for coupling light into the light guide and a second end for coupling light out of the light guide. In addition, an illumination method, and also an illumination system and a method for operating an illumination system are provided.