An optically pumped magnetometer includes cells configured to form a first cell region and a second cell region on a measurement target, a pump laser, a probe laser, a first optical system configured to cause pump light to be incident on the first cell region, a second optical system configured to cause the pump light having passed through the first cell region to be incident on the second cell region, a third optical system configured to cause first probe light to be incident on the first cell region, a fourth optical system configured to cause second probe light to be incident on the second cell region, detection portions configured to detect the first probe light having passed through the first cell region and the second probe light having passed through the second cell region, and a deriving portion configured to derive an intensity of a magnetic field.

A brain measurement apparatus includes: a static magnetic field forming unit for forming a static magnetic field in a measurement area; a gradient magnetic field coil for forming a gradient magnetic field in the measurement area; a transmission coil for transmitting a transmission pulse toward a subject in the measurement area; a detection coil for detecting a nuclear magnetic resonance signal generated in the subject by transmission of the transmission pulse; and a generator for generating an MR image based on the nuclear magnetic resonance signal detected by the detection coil.

Devices for determining a state of a magnetic field-generating article are provided. In various embodiments, a device comprises: a single crystal diamond having a plurality of NV centers, the single crystal diamond configured to be disposed adjacent to a magnetic field-generating article, and configured to generate a fluorescent signal in response to being illuminated by a light source; a coherent light source configured to generate a light beam directed at the single crystal diamond; a microwave (MW) radiation source configured to irradiate the single crystal diamond with a MW signal; a magnetic field source configured to apply a bias magnetic field to the single crystal diamond; a photosensor configured to collect the fluorescent signal generated by the single crystal diamond; and a computing node operatively coupled to each of the coherent light source, the MW radiation source, the magnetic field source, and the photosensor.

The disclosure relates to a receiving unit configured for acquiring MR signals from an examination object in a magnetic resonance device. The receiving unit may include a detector unit comprising a light source and a first optical detector, a sensor unit comprising a first optical magnetometer, a first optical waveguide connecting the sensor unit to the light source, and a second optical waveguide connecting the sensor unit to the first optical detector.

The present application discloses methods and apparatus for detecting a complex including an analyte that include contacting a sample in a solution with a population of functionalized beads of a first type, which are magnetic functionalized beads and are functionalized to include a first moiety that associates with an analyte under suitable conditions, contacting the sample solution with a population of functionalized beads of a second type, which are functionalized to include a second moiety that associates with the analyte under suitable conditions, contact resulting in formation of a complex including one of the first type of functionalized bead, the analyte, and one of the second type of functionalized bead, and detecting the complex including the analyte by detecting magnetic fields produced by the magnetic functionalized bead and by detecting the functionalized bead of the second type associated with the analyte in the complex.

The present application discloses methods and apparatus for detecting a complex including an analyte that include contacting a sample in a solution with a population of functionalized beads of a first type, which are magnetic functionalized beads and are functionalized to include a first moiety that associates with an analyte under suitable conditions, contacting the sample solution with a population of functionalized beads of a second type, which are functionalized to include a second moiety that associates with the analyte under suitable conditions, contact resulting in formation of a complex including one of the first type of functionalized bead, the analyte, and one of the second type of functionalized bead, and detecting the complex including the analyte by detecting magnetic fields produced by the magnetic functionalized bead and by detecting the functionalized bead of the second type associated with the analyte in the complex.

The magnetic resonance member 1 is a member that is arranged in a measurement target AC physical field, and in which a quantum operation can be performed in a specific quantum system. The coil 2 and the high frequency power supply 3 apply a magnetic field of a microwave to the magnetic resonance member 1. The irradiating device 4 irradiates the magnetic resonance member 1 with light, and the detecting device 5 detects from the magnetic resonance member 1 a physical phenomenon corresponding to the measurement target AC physical field. Further, the measurement control unit 21 performs the DC physical field measurement sequence a predetermined plural times, and in each of the plural times of the DC physical field measurement sequence, determines a detection value of the physical phenomenon detected by the detecting device 5.

The calculation unit 22 calculates a measurement result for a specific time span of the measurement target AC physical field on the basis of the detection values corresponding to the plural times of the DC physical field measurement sequence.

An integrated sensor includes a sensor cell, a signal source, an input optical rotator, and a signal detector. The integrated sensor includes a positioner for a signal-processing component. The positioner may be a linear positioner for the signal-processing component, such as a signal source or a signal detector, or may be a rotational positioner for the signal-processing component, such as a polarizer or a polarized signal source. The signal-processing component is located on a signal path of the integrated sensor. A method of adjusting a linear position or rotational position of a signal-processing component is also disclosed. A linear position or a rotational position of the signal-processing component may be adjusted to improve performance of the integrated sensor.

An integrated sensor includes a sensor cell, a signal source, an input optical rotator, and a signal detector. The integrated sensor includes a positioner for a signal-processing component. The positioner may be a linear positioner for the signal-processing component, such as a signal source or a signal detector, or may be a rotational positioner for the signal-processing component, such as a polarizer or a polarized signal source. The signal-processing component is located on a signal path of the integrated sensor. A method of adjusting a linear position or rotational position of a signal-processing component is also disclosed. A linear position or a rotational position of the signal-processing component may be adjusted to improve performance of the integrated sensor.

It is an object of the invention to improve processes, apparatuses and systems for measuring a measured variable. To this end, a measured variable is measured in a measuring process on the basis of an NV center as a quantum sensor. The NV center has a plurality of quantum states and is optically excitable on the basis of an occupancy of one of the quantum states into at least one excited state of the quantum states by means of an excitation light. The at least one excited state can decay at least with emission of emission light of the NV center. In the measuring process, the NV center is irradiated by the excitation light, the excitation light having a time periodic modulation, and a respective occupancy probability and/or a respective lifetime of the quantum states depending on the measured variable and the excitation light. A phase shift is determined between the emission light of the NV center and the modulation of the excitation light and a measurement value for the measured variable is determined on the basis thereof.