A system for hyperpolarizing a substance is provided. The system includes a cryostat, a polarizer, and a shuttle. The cryostat is operative to generate radicals within the substance by exposing the substance to electromagnetic radiation. The polarizer is operative to hyperpolarize the substance via the radicals, and to quench the radicals within the substance by adjusting a temperature of the substance after the substance has been hyperpolarized. The shuttle is operative to transport the substance while maintaining hyperpolarization of the substance.

A method for controlling a magnetic resonance imaging system, including: selecting a plurality of spatially non-selective initial RF-pulses each having a predefined pulse shape and a predefined frequency; determining a combined RF-pulse from the initial RF-pulses by choosing a time-offset comprising a relative application time-shift between the initial RF-pulses, wherein this time-offset is chosen such that the initial RF-pulses overlap; and including the combined RF pulse in a pulse sequence applied in a magnetic resonance imaging system.

According to one embodiment, a MRI apparatus includes an RF coil apparatus receiving MR signals by coil elements corresponding to channels, modulating the MR signals to have different frequencies for each of the channels, and outputting an analog multiplexed signal in which the MR signals with different frequencies are composited over the channels, and a receiver including ADC circuitry converting the analog multiplexed signal to a digital multiplexed signal, and predetermined number of separation channels separating the digital multiplexed signal, based on the number of the channels relating to composition of the MR signals with the different frequencies. The receiver stops a separation process of the digital multiplexed signal for separation channels not used in the separation process among the predetermined number of separation channels.

A dual- or multi-resonant RF/MR transmit and/or receive antenna (1, 2) especially in the form of a planar antenna or a volume array antenna (also called antenna array) is used for MR image generation of at least two different nuclei like e.g. .sup.1H, .sup.19F, .sup.3He, .sup.13C, .sup.23Na or other nuclei having different Larmor frequencies. The antenna is coupled by an inductive coupling device (LI) with related transmit/receive channels (T/R). By such an inductive coupling, the tuning and matching of the antenna at the different resonant frequencies is easier than in case of a galvanic connection. The dual- or multi-resonant RF/MR transmit and/or receive antenna is used in an MR imaging apparatus.

Techniques for crushing unwanted coherence pathways during magnetic resonance spectral (MRS) measurements include receiving first data that indicates a sequence of RF pulses with one or more target coherence pathways of spin states for a subject that has at least N1 coupled spin states of interest. A negative, non-integer amplitude is determined for at least one intervening crusher pulse emitted from at least one spatial gradient magnetic coil. The at least one intervening crusher pulse has a duration less than a time between successive pulses of the sequence of RF pulses; and, the intervening crusher pulse de-phases unwanted coherence pathways. A MRS device is operated using the intervening crusher pulse and the sequence of RF pulses.

A system and method for detecting a nucleus of interest in a chemical using a nuclear quadrupole resonance transition. An excitation pulse is used to excite one or more nuclei of interest, if they present in a sample, to an excited state, the energy of which depends on the magnetic field in the sample. The magnetic field in the sample is modulated, after the end of the excitation pulse, while the nuclei of interest decay from the excited state, so that the radiation they emit is frequency modulated. The frequency modulation is detected in the emitted radiation. In some embodiments a DC magnetic field is applied to the sample, during the application of the excitation pulse, to tune the frequency of the transition being excited.

A system for hyperpolarizing a substance is provided. The system includes a cryostat, a polarizer, and a shuttle. The cryostat is operative to generate radicals within the substance by exposing the substance to electromagnetic radiation. The polarizer is operative to hyperpolarize the substance via the radicals, and to quench the radicals within the substance by adjusting a temperature of the substance after the substance has been hyperpolarized. The shuttle is operative to transport the substance while maintaining hyperpolarization of the substance.

Systems and methods for magnetic resonance imaging (MRI) of multiple different nuclear spin species using the same radio frequency (RF) coil are described. Generally, multiple different nuclear spin species are imaged using the same RF coil by using an MRI system whose magnetic field can be rapidly ramped between a number of different, and arbitrary, magnetic field strengths. The magnetic field of this MRI system can be ramped to different values in reasonable amounts of time (e.g., in a time frame that is feasible within an imaging study).

A magnetic resonance imaging (MRI) system and method integrating multi-nuclide synchronous imaging and spectral imaging is provided. The MRI system includes a spectral imaging module, a multi-nuclide synchronous imaging module, and a spectral reconstruction and image fusion module, where the spectral imaging module is configured to acquire a spectrum of a nuclide Nuc; the multi-nuclide synchronous imaging module is configured to perform synchronous imaging of nuclides Nuc1 . . . . Nucn, where when n=1, Nucl is .sup.1H; and when n>1, Nucn is a non-.sup.1H nuclide; and the spectral reconstruction and image fusion module is configured to receive the spectrum of the nuclide Nuc and images of the nuclides Nuc1 . . . . Nucn, and acquire spatial distribution information of compounds of the nuclide Nuc and spatial distribution information of the non-.sup.1H nuclide through fusion. The system and method can synchronously acquire MR signals of different nuclides, and reconstruct and fuse non-.sup.1H nuclide images.

Eddy current induced magnetic fields (MF) are compensated in a magnetic resonance imaging system. An MR-sequence (M) includes a number of gradients. A dataset includes values of an amplitude and a time constant of eddy current fields of a number of gradients on at least one gradient axis. A number of points in time within the time period of the MR-sequence are defined. A number of constant currents are calculated for a number of coils of the magnetic resonance imaging system based on the dataset. The number of constant currents is designed to compensate at least at the one defined point in time (PT1, PT2). The calculated number of constant currents are applied on the related coils prior or during the application of the MR-sequence or a section of the MR-sequence.