Patent classifications
G01R33/46
Device and method for nuclear magnet resonance spectroscopy
A device for NMR spectroscopy includes a magnet arrangement, configured to produce a magnetic probe field within a magnet field of view external to the magnet arrangement. In a embodiment, the device includes a coil arrangement, configured to generate an electromagnetic excitation field within a coil field of view and a controller, configured to control the coil arrangement. The device includes a magnet adjustment arrangement, configured and arranged to modify at least one parameter of the magnet arrangement to change a spatial position of the magnet field of view.
METHOD FOR DETECTING SPINS BY PHOTON COUNTING
A method of detecting spins in a sample, includes exciting the spins of the sample by means of a radio-frequency or microwave electromagnetic pulse for flipping the spins, and detecting a noise signal produced by the return of the spins to equilibrium by means of a device for counting radio-frequency or microwave photons.
ESTERIFIED ACIDS FOR USE IN POLYMERIC MATERIALS
The present teachings contemplate a method that includes a step of providing a first amount of esterified reaction product of an acid and an epoxy-based material. The esterified reaction product may be further reacted an epoxy resin to form a polymeric epoxy. The resulting material may have a generally linear backbone, foaming and curing capability and flame retardant properties.
Dinitroxide biradical compounds as polarizing agents
The present invention relates to novel organic dinitroxide biradical compounds and their use as polarizing agents, in particular, in the techniques of Nuclear Magnetic Resonance (NMR) of solids or liquid samples and medical imaging.
Magnetic resonance spectroscopy pulse sequence, acquisition, and processing system and method
Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.
MAGNETIC RESONANCE SPECTROSCOPY PULSE SEQUENCE, ACQUISITION, AND PROCESSING SYSTEM AND METHOD
Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.
Method for Determination of the Anisotropic Parameters for the Configuration of Organic Molecules Embedded in Alignment Media
A method for determination of molecular parameters for a configuration of a known single organic molecule embedded in an anisotropic environment generated by alignment media, said known single organic molecule comprising particles, is disclosed. The method comprising the steps of: a) Defining a three-dimensional grid that is aligned with the known atomic structure of the alignment medium; b) Placing the particles of the known single organic molecule on the respective grid points of the three-dimensional grid in relation to at least one assigned atom of the alignment medium; c) Determining the interaction between the particles of the single organic molecule and the alignment medium for a set of orientations and a plurality of configurations of the particles; d) Calculating anisotropic parameters obtainable by measuring with nuclear magnetic resonance (NMR) spectroscopy by use of the determined interactions for each of the plurality of configurations of the organic molecule.
PNEUMATIC CABLE SHUTTLE SYSTEM FOR 2FNMR
A transfer device is provided for shuttling an NMR sample container between at least two coaxially arranged NMR magnet systems of an NMR spectrometer comprising a guide tube positioned in a central bore of the magnet systems, a shuttle assembly arranged inside the guide tube for securely holding and shuttling the sample container and a drive system comprising a pulling drive and a winch cord attached to the drive system on one side and to the shuttle assembly on the other side, such that the shuttle assembly can travel inside the guide tube. The transfer device has a pneumatic pressurizing arrangement with an entry for pressurized gas arranged on a gas-tight body above the shuttle assembly that is adapted to maintain the winch cord under tension. The shuttle assembly comprises a piston design being moveable along the common axis of the coaxial magnet systems under the influence of the pressure.
PNEUMATIC CABLE SHUTTLE SYSTEM FOR 2FNMR
A transfer device is provided for shuttling an NMR sample container between at least two coaxially arranged NMR magnet systems of an NMR spectrometer comprising a guide tube positioned in a central bore of the magnet systems, a shuttle assembly arranged inside the guide tube for securely holding and shuttling the sample container and a drive system comprising a pulling drive and a winch cord attached to the drive system on one side and to the shuttle assembly on the other side, such that the shuttle assembly can travel inside the guide tube. The transfer device has a pneumatic pressurizing arrangement with an entry for pressurized gas arranged on a gas-tight body above the shuttle assembly that is adapted to maintain the winch cord under tension. The shuttle assembly comprises a piston design being moveable along the common axis of the coaxial magnet systems under the influence of the pressure.
Method for measuring the gradient field of a nuclear magnetic resonance (NMR) system based on the diffusion effect
A method for measuring a gradient field of a nuclear magnetic resonance (NMR) system based on a diffusion effect uses a non-uniform field magnet, an NMR spectrometer, a radio frequency (RF) power amplifier, an RF coil, and a standard quantitative phantom with known apparent diffusion coefficient (ADC) and time constant for decay of transverse magnetization after RF-pulse (T2). A plurality of sets of signals are acquired by an NMR sequence with different diffusion-sensitive gradient durations or different echo spacings and the magnitude of the gradient field is calculated by fitting based on the plurality of sets of signals. The method does not require an additional dedicated magnetic field detection device, has a short measurement time, is easy to use with the NMR system, and is convenient to complete gradient field measurement at the installation site, thereby improving the installation and service efficiency of the NMR system.