A lens including a flexible refractive optic having a fixed refractive index, an electro-active element embedded within the flexible refractive optic, wherein the electro-active element has an alterable refractive index, and a controller electrically connected to the electro-active element wherein when power is applied thereto the refractive index of the electro-active element is altered.

A lens including a flexible refractive optic having a fixed refractive index, an electro-active element embedded within the flexible refractive optic, wherein the electro-active element has an alterable refractive index, and a controller electrically connected to the electro-active element wherein when power is applied thereto the refractive index of the electro-active element is altered.

The disclosure relates to novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same. More particularly, the disclosure relates to relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting IOLs made therefrom.

The disclosure relates to novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same. More particularly, the disclosure relates to relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting IOLs made therefrom.

Bioactive polymers, including methods, compositions, and devices, for ophthalmic applications. The methods may include selecting a bioactive agent, conjugating the bioactive agent to a moiety to produce a bioactive monomer, and then performing a copolymerization reaction using as reactants the bioactive monomer and one or more other monomers each lacking the bioactive agent. The moiety of the bioactive monomer may react directly with at least one of the other monomers in the copolymerization reaction.

An eyeglass lens material can be used to make an eyeglass lens and at least includes a mixture of Ag/SiO.sub.x composite nanoparticles and at least one type of monomer. The eyeglass lens is capable of blocking blue light. The monomer undergoes a material curing procedure to form a main body that contains and is mixed with the Ag/SiO.sub.x composite nanoparticles. As the Ag/SiO.sub.x composite nanoparticles in the eyeglass lens material can absorb relatively high-energy blue light, a contact lens made of the eyeglass lens material can block blue light.

In certain embodiments, the systems, apparatus, and methods disclosed herein relate to robotic surgical systems with built-in navigation capability for patient position tracking and surgical instrument guidance during a surgical procedure, without the need for a separate navigation system. Robotic based navigation of surgical instruments during surgical procedures allows for easy registration and operative volume identification and tracking. The systems, apparatus, and methods herein allow re-registration, model updates, and operative volumes to be performed intra-operatively with minimal disruption to the surgical workflow. In certain embodiments, navigational assistance can be provided to a surgeon by displaying a surgical instrument’s position relative to a patient’s anatomy. Additionally, by revising pre-operatively defined data such as operative volumes, patient-robot orientation relationships, and anatomical models of the patient, a higher degree of precision and lower risk of complications and serious medical error can be achieved.

Described are polymerizable high energy light absorbing compounds of formula I:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, and X are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Described are polymerizable high energy light absorbing compounds of formula I:

##STR00001##

wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, and X are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

An electrically-switchable flexible contact lens for conforming to an eye of a user is provided. The lens comprises a liquid crystal cell for changing a focal power of the contact lens, and the liquid crystal cell has a cell gap thickness between a first inner surface and a second inner surface, the liquid crystal cell comprising a diffractive optical element for correcting the vision of a user, wherein the diffractive optical element is arranged to maintain the cell gap thickness by providing support at one or more locations within the cell.