An image quality is improved although a medical stereomicroscope optical system and a medical observation apparatus are small and light. An objective optical system and a plurality of imaging optical systems are arranged in an order from an object side to an image side, and the imaging optical system has at least a single aspheric surface. Accordingly, a spherical aberration and a field curvature are improved, and the image quality is improved although the medical stereomicroscope optical system and a medical observation apparatus are small and light.

An image quality is improved although a medical stereomicroscope optical system and a medical observation apparatus are small and light. An objective optical system and a plurality of imaging optical systems are arranged in an order from an object side to an image side, and the imaging optical system has at least a single aspheric surface. Accordingly, a spherical aberration and a field curvature are improved, and the image quality is improved although the medical stereomicroscope optical system and a medical observation apparatus are small and light.

To achieve improvement in functionality resulting from switching of optical elements and miniaturization of the device. A medical observation device includes: an imaging optical system configured to capture an image of a subject; an image sensor configured to photoelectrically convert the image of the subject captured by the imaging optical system; and an element holding frame configured to hold a plurality of optical elements and to be capable of being rotated around a rotation shaft. An axial direction of the rotation shaft is set to a direction orthogonal to an optical axis direction that is a direction of a line from the imaging optical system to the image sensor, and the element holding frame is rotated and thus at least one of the optical elements among the plurality of optical elements is positioned on an optical axis. Thereby, the element holding frame is rotated around a rotation shaft whose axial direction is set to the direction orthogonal to the optical axis direction and thus at least one of the plurality of optical elements is positioned on the optical axis, and therefore it is possible to achieve improvement in functionality resulting from switching of the optical elements and miniaturization of the device.

An ophthalmic surgical system includes an imaging unit configured to generate a fundus image of an eye and a depth imaging system configured to generate a depth-resolved image of the eye. The system further includes a tracking system communicatively coupled to the imaging unit and depth imaging system, the tracking system comprising a processor and memory configured to analyze the fundus image generated by the imaging unit to determine a location of a distal tip of a surgical instrument in the fundus image, analyze the depth-resolved image generated by the depth imaging system to determine a distance between the distal tip of the surgical instrument and a retina of the eye, generate a visual indicator to overlay a portion of the fundus image, the visual indicator indicating the determined distance between the distal tip and the retina, modify the visual indicator to track a change in the location of the distal tip within the fundus image in real-time, and modify the visual indicator to indicate a change in the distance between the distal tip of the surgical instrument and the retina in real-time.

One aspect of the invention provides a method for drift correction to correct a 3D point collection dataset to compensate for drift over time. The method includes: (a) separating the 3D dataset into n segments, wherein n>1; (b) for each of the n segments, reconstructing a volume image as a 3D histogram in which a count for each voxel in the histogram equals a number of localization estimates falling within the voxel; (c) performing 3D cross-correlation between pairs of the n segments; (d) identifying a correlation peak in a result of the 3D cross-correlation to determine a shift distance between pairs of the n segments; (e) solving an overdetermined system of shift distances to determine independent shifts; and (f) offsetting positions from a plurality of segments in the 3D point collection dataset with the independent shifts calculated in step (e) to correct for drift.

One aspect of the invention provides a method for drift correction to correct a 3D point collection dataset to compensate for drift over time. The method includes: (a) separating the 3D dataset into n segments, wherein n>1; (b) for each of the n segments, reconstructing a volume image as a 3D histogram in which a count for each voxel in the histogram equals a number of localization estimates falling within the voxel; (c) performing 3D cross-correlation between pairs of the n segments; (d) identifying a correlation peak in a result of the 3D cross-correlation to determine a shift distance between pairs of the n segments; (e) solving an overdetermined system of shift distances to determine independent shifts; and (f) offsetting positions from a plurality of segments in the 3D point collection dataset with the independent shifts calculated in step (e) to correct for drift.

A surgical microscope system includes a camera that is rotatable around a first rotation axis and a second rotation axis, the rotation axes being orthogonal to each other, so that a photographing direction of the camera is changeable at a given position. The first rotation axis is inclined with respect to a vertical axis, and therefore, a lower end of a first member is able to be set at a height that does not interfere with the photographing direction when the camera is horizontally oriented.

A surgical microscope system includes a camera that is rotatable around a first rotation axis and a second rotation axis, the rotation axes being orthogonal to each other, so that a photographing direction of the camera is changeable at a given position. The first rotation axis is inclined with respect to a vertical axis, and therefore, a lower end of a first member is able to be set at a height that does not interfere with the photographing direction when the camera is horizontally oriented.

An operating microscope includes an objective lens, a first illumination optical system, a deflector, and an observation optical system. The first illumination optical system is arranged coaxially with an optical axis of the objective lens and is configured to be capable of illuminating first illumination light onto an eye to be operated through the objective lens. The deflector is configured to deflect returning light of the first illumination light in a direction intersecting the optical axis, the returning light being incident from the eye to be operated through objective lens. The observation optical system is configured to be capable of guiding the returning light deflected by the deflector to an eyepiece lens or an imaging element.

An operating microscope includes an objective lens, a first illumination optical system, a deflector, and an observation optical system. The first illumination optical system is arranged coaxially with an optical axis of the objective lens and is configured to be capable of illuminating first illumination light onto an eye to be operated through the objective lens. The deflector is configured to deflect returning light of the first illumination light in a direction intersecting the optical axis, the returning light being incident from the eye to be operated through objective lens. The observation optical system is configured to be capable of guiding the returning light deflected by the deflector to an eyepiece lens or an imaging element.