An automatic focus system for an optical microscope that facilitates faster focusing by using at least two offset focusing cameras. Each offset focusing camera can be positioned on a different side of an image forming conjugate plane so that their sharpness curves intersect at the image forming conjugate plane. Focus of a specimen can be adjusted by using sharpness values determined from images taken by the offset focusing cameras.

The invention relates to a microscope, comprising a stage (13); an x motor, a y motor, and a z axis focusing driving mechanism that drive the stage to move along left-right, front-rear, and up-down directions respectively; a controller; at least one knob (3) which is operatively coupled to the x motor and/or y motor or the z axis focusing driving mechanism selectively by means of the controller to control operation of the coupled motor or the coupled z axis focusing driving mechanism; and at least one button (4, 5) which is coupled to the controller in communication and sends to the controller a button signal indicating that the button has been triggered by operation of the microscope user. The controller is configured to disconnect a normal operative coupling between the knob (3) and the z axis focusing driving mechanism and establish an operative coupling between the knob and the x motor and/or y motor when receiving a predetermined button signal, and restore the normal operative coupling between the knob (3) and the z axis focusing driving mechanism and disconnect the operative coupling between the knob and the x motor and/or y motor when no longer receiving the predetermined button signal or when receiving a next button signal.

An apparatus for scanning microscope slides is provided. The apparatus includes an objective; a specimen stage; a camera sensor configured to capture a first plurality of images at a first rate while focus is changed in continuous motion; and a flash unit configured to flash at a second rate, wherein the first rate and the second rate are synchronized.

The present description relates to a device that includes: a microscope lens with an optical axis; a mounting that includes a distal portion, in which the microscope lens is arranged; a first end piece fixed in a removable manner, in a first operating mode for in vivo microscopic analysis of the skin, to the distal portion of the mounting; a second end piece fixed in a removable manner, in a second operating mode for ex vivo microscopic analysis of a sample, to the distal portion of the mounting; a sample carrier with a receiving surface; a support that cooperates with the second end piece in the second operating mode so as to receive the mounting so that the optical axis of the microscope lens is substantially aligned in a predetermined direction with respect to the receiving surface.

A well tray includes a base including an upper surface, a lower surface and at least one edge surface connecting the upper surface to the lower surface. The at least one edge surface defines a slot. The slot is in communication with a magnet receiver at least partially defined between the upper surface and the lower surface. The magnet receiver is configured to slidably receive a removable magnet. The tray includes a plurality of wells disposed on an upper surface of the base.

A method for manipulating at least one beam path in a microscope includes ascertaining a refractive index of a sample arranged in a sample volume and/or of an optical medium arranged in the sample volume. At least one microscope parameter is set in dependence on the ascertained refractive index for manipulating the beam path.

The present description relates to a device that includes: a microscope lens with an optical axis; a mounting that includes a distal portion, in which the microscope lens is arranged; a first end piece fixed in a removable manner, in a first operating mode for in vivo microscopic analysis of the skin, to the distal portion of the mounting; a second end piece fixed in a removable manner, in a second operating mode for ex vivo microscopic analysis of a sample, to the distal portion of the mounting; a sample carrier with a receiving surface; a support that cooperates with the second end piece in the second operating mode so as to receive the mounting so that the optical axis of the microscope lens is substantially aligned in a predetermined direction with respect to the receiving surface.

A control device for a microscope includes an actuator configured to shift a microscopic field of view relative to a sample, and an operating device configured to be operated by a user to control the actuator in accordance with a response characteristic determining a shift sensitivity. The field of view is shifted relative to the sample in response to a user operation of the operating device. The control device further includes a processor configured to determine a total visual magnification, and to control the response characteristic of the operating device based on the total visual magnification. The field of view is visualized by the microscope to the user based on the total visual magnification.

The present disclosure provides a microscopic imaging system. The microimaging system includes a sample platform control structure and/or a platform mechanism for the microscopic imaging system. The sample platform control structure includes a base, an X platform, an X platform moving mechanism, a sample platform, a sample platform moving mechanism, a primary guide rail, and a secondary guide rail. The platform mechanism for the microscopic imaging system includes the sample platform control structure and a Y platform, a Y platform moving mechanism, a Z platform, a Z platform moving mechanism, and an imaging device.

An automatic focus system for an optical microscope that facilitates faster focusing by using at least two offset focusing cameras. Each offset focusing camera can be positioned on a different side of an image forming conjugate plane so that their sharpness curves intersect at the image forming conjugate plane. Focus of a specimen can be adjusted by using sharpness values determined from images taken by the offset focusing cameras.