The current invention concerns a method for detecting cancerous cells and/or classifying cells in a cell sample comprising the following steps: providing a cell sample; obtaining holographic information from said cell sample by digital holographic microscopy (DHM); deriving at least one cellular parameter from said holographic information, and; classifying said cells of cells sample; characterized in that said classification occurs by appointing a Scoring Factor to said cells of cell sample, based on said cellular parameters. In a second aspect, a system for the detection of cancerous cells and/or classification of cells in a cell sample is provided, employing the method as disclosed in the invention. In a final aspect, a method for updating and/or improving a database comprising thresholds linked to holographic information and the database related thereof is equally disclosed.

The present invention relates to a system and method for displaying and capturing holographic true 3D images. The system comprises elements which may form both a wide viewing angle holographic true 3D display and a holographic true 3D video camera. The system mainly comprises a light source, a spatial light modulator or an electro-optical capturing device in different embodiments of the invention, a phase plate, a computer and an opaque mask in some embodiments of the invention.

An apparatus for producing a hologram includes a collimation lens configured to receive incoherent light emitted from an object; a spatial light modulator (SLM) that includes at least one diffractive lens which is configured to receive the incoherent light from the collimation lens and split the incoherent light into two beams that interfere with each other; and a camera configured to record the interference pattern of the two beams to create a hologram, wherein a ratio between a distance from the SLM to the camera and a focal length of the diffractive lens is greater than 1.

An infrared imaging system includes a phase grating overlying a two-dimensional array of thermally sensitive pixels. The phase grating comprises a two-dimensional array of identical subgratings that define a system of Cartesian coordinates. The subgrating and pixel arrays are sized and oriented such that the pixels are evenly distributed with respect to the row and column intersections of the subgratings. The location of each pixel thus maps to a unique location beneath a virtual archetypical subgrating.

Provided is a high-resolution reflection tomographic imaging system and method. The high-resolution reflection tomographic imaging system of the present disclosure may include an objective lens, a tube lens, a camera, an illumination element configured to introduce temporally coherent and spatially incoherent light, and a semi-reflective surface element configured to split the light into a sample and a reference beam between the tube lens and the camera, such that a sample beam from the sample and the reference beam cause interference for tomographic imaging.

Example apparatuses and methods relating to imaging systems are provided. An example imaging system may include an optical source configured to generate an optical beam, a beam splitter configured to split the optical beam into a reference beam and an object beam, and a beam combiner configured to route a combined beam with reference beam and object beam components along a common path into a target medium. In this regard, the target medium may act upon the combined beam to form a common path interference beam. The example imaging system may further include an imaging sensor configured to receive the common path interference beam and generate common path interference beam data associated with the common path interference beam, and an image data processor configured to analyze the common path interference beam data to generate image data describing the target medium.

A neural imaging system may include an imaging array, an image data processor operably coupled to the imaging array to process image data received from the imaging array, and a beam angle separator disposed between the imaging array and an object being imaged. The beam angle separator may be configured to separate an object beam reflected from the object being imaged into a plurality of reference beams each having different angular separation with respect to the object beam. The image data processor may be configured to generate image data of the object for each one of the reference beams to correspond to a respective different depth within the object.

The image observation apparatus introduces an object light, which is at least part of an object illumination light emitted from a light source and projected onto an object and which is reflected by the object, through a first optical waveguide to an image sensor, introduces a reference light, which is emitted from the light source and passes through an optical path different from that of the object light, to the image sensor, and records an interference fringe through the image sensor as a hologram. The apparatus forms the recorded hologram on a spatial light modulator and illuminate the modulator with a hologram illumination light corresponding to the reference light to generate a reconstruction light, and causes the reconstruction light entering a second optical waveguide optically equivalent to the first optical waveguide and exiting from the second optical waveguide to form an object reconstructed image.

An apparatus and method to produce a hologram of a cross-section of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation. An image capture assembly is configured to capture an image of the diffracted electromagnetic radiation and produce the hologram of the cross-section of the object from the captured image. The hologram of the cross-section includes information regarding a single cross-section of the object.

In one embodiment, a self-interference incoherent digital holography system including a light sensor and a diffractive filter configured to receive light from an object to be holographically imaged and generate holographic interference patterns on the light sensor. A self-interference incoherent digital holography system comprising: a light sensor; and a diffractive filter configured to receive light from an object to be holographically imaged and generate holographic interference patterns on the sensor.