A neural imaging system may include an imaging array, an image data processor operably coupled to the imaging array to process image data received from the imaging array, and a beam angle separator disposed between the imaging array and an object being imaged. The beam angle separator may be configured to separate an object beam reflected from the object being imaged into a plurality of reference beams each having different angular separation with respect to the object beam. The image data processor may be configured to generate image data of the object for each one of the reference beams to correspond to a respective different depth within the object.

The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.

A digital holographic microscope is provided. The digital holographic microscope includes a light source, a grating, an image sensing device, and an optical module. The light source is configured for providing a light beam. The grating is disposed between the light source and a sample. The grating is configured for splitting the light beam into a reference light beam and an object light beam. The image sensing device is configured for collecting the reference light beam, and collecting the object light beam reflected from the sample. The optical module is disposed between the light source and the sample, and is configured for guiding the reference light beam to the image sensing device, and guiding the object light beam to the sample.

A holographic 3D recording device includes: a photorefractive crystal and a microlens array. The microlens array includes an array face and a side face. The microlens array is provided in a light path from an object to be photographed to the photorefractive crystal such that first light of object emitted through a diffuse reflection of the object to be photographed passes through the array face of the microlens array and becomes second light of object that is emitted to the photorefractive crystal. The photorefractive crystal is configured to receive the second light of object emitted by the microlens array and reference light, respectively, and save therein an interference fringe formed by the reference light and the second light of object. The first light of object and the reference light are coherent light.

A holography imaging system includes a first laser, a second laser, a transmitter optical system, a receiver optical system, and a detector array. The first laser has a constant frequency, and the second laser has a non-constant frequency. The transmitter optical system can illuminate a target simultaneously using portions of the first and second laser signals. The receiver optical system can focus a returned light onto the detector array. A first and second illumination point sources can direct portions of the first and second laser signals onto the detector array. The first and second illumination point sources are located in-plane with a pupil of the receiver optical system. The system can detect simultaneously holograms formed on the detector array based on the returned light and the portions of the first and second laser signals directed by the first and second illumination point sources.

Imaging apparatus and methods using diffraction-based illumination are disclosed. An example apparatus includes a diffraction grating to redirect light from a light source toward a sample to thereby illuminate the sample. The example apparatus also includes an image sensor to detect a diffraction pattern created by the illuminated sample.

A lighting device for vehicles includes a light source unit containing numerous light sources, and includes a hologram unit containing numerous hologram segments for generating a predefined light distribution. The hologram segments form reflection hologram segments behind and/or next to the light source unit in the main beam direction (H) of the lighting device, such that light emitted from the light source strikes the reflection hologram segment at an acute angle ). Holographic diffraction information is stored in the reflection hologram segments for generating a signal light distribution. The light source unit contains just one printed circuit board or one printed circuit board substrate.

Systems and methods are provided for a digital holography system. The subject system uses wide-bandwidth data, monitor beams, and signal beams to form a digital interference, yielding a reference phase and angle that can be used to compensate DH phase errors. DH systems disclosed herein can provide an ability to sense and correct for phase errors and/or instabilities to perform DH vibrometry. Such a system provides a compact and low-cost solution to improve sensing in, for example, systems that rely on phase stability for precision 3D and/or vibration imaging.