Aspects of the disclosure relate to methods of conducting an intraoperative procedure including providing an electrode assembly having a pledget substrate having a surface that is hydrophilic, at least one electrode supported by and positioned within the pledget substrate, and a lead wire assembly interconnected to the at least one electrode. Methods can further include creating an incision to access bioelectric tissue of a patient and applying the pledget substrate to the tissue, such as a nerve, for example. The pledget substrate conforms and fixates to the tissue to secure the electrode assembly in position. The electrode is then activated to record bioelectric responses of or stimulate the tissue. In some embodiments, the pledget substrate includes two bodies, each including at least one electrode, the two bodies being selectively separable so that the bodies can be repositioned with respect to one another.

A non-invasive system for monitoring brain trauma, the system comprising: a plurality of spaced apart brainwave sensors configured to monitor brainwaves of a user of the system; one or more force determination sensors, configured to determine an amount of force exerted on the user's head; and a processing unit configured to: obtain a plurality of brainwave readings from the brainwave sensors and a plurality of force readings from the force determination sensors; provide a notification upon the force readings indicating that the amount of force exerted on the user's head exceeds a threshold or upon the brainwave readings indicating an abnormal brain activity.

A system for characterization of a brain tissue sample includes a laser having an excitation fiber and a probe coupled to the excitation fiber for irradiating the brain tissue sample with light at an excitation wavelength. The probe further includes a plurality of return fibers for receiving light scattered from the brain tissue sample, wherein each return fiber includes a microfilter that permits light to pass for a different, spaced apart marker region. A Raman spectrometer is in communication with the plurality of return fibers, and a processor is in communication with the Raman spectrometer for analyzing Raman spectra within the marker regions to identify a tissue type of the brain tissue sample as one of normal white matter brain tissue, normal grey matter brain tissue, brain tumor tissue, infiltrating tumor tissue, and necrotic tissue.

A measuring instrument attachment assist device which includes: a coordinate detector which detects coordinates of predetermined feature points from an image obtained by capturing an image of a subject; a conversion parameter calculator which calculates a projection conversion parameter for converting the coordinates of the feature points in a model image into the coordinates obtained by the detection; a designating unit which designates a position of a measuring instrument attached to the subject in the model image; a coordinate converter which converts a coordinate of the position designated by using the designating unit, by using the projection conversion parameter; and a display which displays the coordinate obtained by the conversion by the coordinate converter, on the image obtained by the capturing.

An illustrative system may include a component configured to be worn on a body of a user, the component comprising a time-to-digital converter (TDC) configured to: receive, during a predetermined event detection time window that commences in response to an application of a light pulse to a target within the body, a signal triggered by an event in which a photodetector detects a photon of the light pulse after the light pulse reflects from the target; and measure, based on the receiving the signal, a time interval between when the event occurred and an end of the predetermined event detection time window. The system may further include a processor configured to determine, based on the time interval and the predetermined event detection time window, an arrival time of the photon at the photodetector.

The medical information display apparatus includes a first data acquisition unit that acquires a table showing relevance between at least one item included in clinical diagnostic information on dementia and a brain area, a second data acquisition unit that acquires clinical diagnostic information on dementia of a subject, an image acquisition unit that receives an input of a three-dimensional brain image, a brain area division unit that divides the three-dimensional brain image of the subject, an image analysis unit that calculates an analysis value for each brain area, an operation unit that selects one item among items included in the clinical diagnostic information of the subject, a display unit, and a display controller that specifies a brain area corresponding to the one item selected by the operation unit and displays brain area specifying information for specifying the specified brain area and an analysis value of the brain area.

Problem To provide an apparatus for evaluating biological function, and a method and a program for evaluating biological function, for the purpose of measuring and quantifying biological function, to make possible the quantification of measured values concerning brain characteristics at time of rest.

Means for resolution The apparatus for evaluating biological function (1) is [an apparatus] that utilizes the near-infrared spectroscopy method to evaluate biological function; measuring part 5 computes time course change amounts of oxyhemoglobin and time course change amounts of deoxyhemoglobin, based on light information from detecting parts 4; and it has a computing part 8, which obtains a group of zeroset vectors at prescribed sampling times based on 2-dimensional diagrams showing the relationship between change amounts of oxyhemoglobin and change amounts of deoxyhemoglobin, and computes parameters based on the directions and/or scalars of that vector group.

A system for providing neuronal stimulation signals configured to elicit sensory percepts in the cortex of an individual, comprising means for obtaining spatial information relating to the actual or planned position of a neuronal stimulation means relative to afferent axon(s) targeting sensory neuron(s) in the cortex of the individual and means for determining a neuronal stimulation signal to be applied to the afferent axon(s) via the neuronal stimulation means based at least in part on the obtained spatial information.

A system for communicating conceptual information to an individual, comprising means for selecting a neuronal stimulation signal to be applied to afferent axon(s) targeting sensory neuron(s) in the cortex of the individual, wherein the neuronal stimulation signal corresponds to the conceptual information to be communicated and means for transmitting the neuronal stimulation signal to the neuronal stimulation means of the individual.

Provided are a disease-condition assessment device for assessing a disease condition of a subject, a disease-condition assessment method, a program for disease-condition assessment device, and a disease-condition assessment system. The disease condition assessment device acquires a data of a seat pressure distribution on a seating surface where a subject operating a vehicle is seated, calculates a center position depending on the seat pressure distribution, calculates a degree of laterality in the seat pressure distribution based on the center position, and assesses a disease condition of the subject depending on the degree of laterality.

A method for determining position of an electrode lead inside a body tissue, including: receiving electrical signals recorded from at least one macro electrode contact of an electrode lead positioned inside a body tissue; extracting spiking (SPK) signals from the received electrical signals; providing stored measurements or indications thereof; determining a position of the lead and/or the at least one macro electrode contact inside said body tissue based on the extracted SPK signals and the provided stored measurements or indications thereof.