A blood pressure monitor configured to removably mount to a cuff in a substantially symmetrical position with respect to a width of the cuff can include a housing defining an interior, a first port, and a second port. The first port can: secure to a first prong of the cuff when the cuff is mounted in a first orientation; receive and secure to a second prong of the cuff when the cuff is mounted in a second orientation; and enable fluid communication between the interior and at least one of a first fluid passage within the first prong and a second fluid passage within the second prong. The second port can: secure to the second prong of the cuff when the cuff is mounted in the first orientation; and receive and secure to the first prong of the cuff when the cuff is mounted in the second orientation.

This document describes methods and materials for mapping and modulating repolarization. For example, this document relates to methods and devices for mapping and modulating repolarization to target atrial and ventricular arrhythmias to deliver electrical stimulation pacing, ablation and/or electroporation.

Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Systems for obtaining an image of a target are provided including at least one multi-wavelength illumination module configured to illuminate a target using two or more different wavelengths, each penetrating the target at different depths; a multi-wavelength camera configured to detect the two or more different wavelengths illuminating the target on corresponding different channels and acquire corresponding images of the target based on the detected two or more different wavelengths illuminating the target; a control module configured synchronize illumination of the target by the at least one multi-wavelength illumination module and detection of the two or more different wavelengths by the camera; an analysis module configured to receive the acquired images of the target and analyze the acquired images to provide analysis results; and an image visualization module modify the acquired images based on the analysis results to provide a final improved image in real-time.

Methods, systems, and apparatuses are described for automated external defibrillation for determining shock/no-shock decisions based on ECG readings taken when a patient is undergoing cardiopulmonary resuscitation (CPR). A device may filter an ECG signal of a patient to reduce artifacts from the signal caused by CPR being performed on the patient. The device may use the filtered ECG signal to determine whether to deliver a therapeutic shock to a patient even if the patient is undergoing CPR.

A training simulator for intraoperative neuromonitoring (IONM) systems includes channels where at least one of the channels is identified as an active stimulation channel and a subset of the rest of the channels is identified as reference or pick up sites. Channels of the subset having signal data that exceed a predefined threshold are retained for further processing, while channels with signal data that do not exceed the threshold are eliminated from further reporting. Response data for the remaining channels are generated in advance of a future time when the response would occur. The generated data is time stamped and stored for display at a time window when requested by the system.

Techniques for sensing neural responses such as Evoked Compound Action Potentials (ECAPs) in an implantable stimulator device are disclosed. A first therapeutic pulse phase is followed by a second pulse phase, which phases may be of opposite polarities to assist with active charge recovery. The second pulse phase is formed so as to overlap in time with the arrival of the ECAP at a sensing electrode, which second phase may generally be longer and of a lower amplitude. In so doing, a stimulation artifact formed in a patient's tissue is rendered constant, and of a smaller amplitude, when the ECAP is sensed at the sensing electrode, which eases sensing by a sense amp circuit. Passive charge recovery may follow the second phase, which will not interfere with ECAP sensing that has already occurred.

The present disclosure provides computer-implemented methods, systems, and devices for improved skin temperature monitoring. Accurate estimates of skin and ambient temperature are generated based on determinations and comparisons of skin and internal device temperature sensor measurements contained on or within example devices. The estimates of skin and ambient temperature measurements facilitate monitoring skin and core temperature changes, detecting physiological events of a wearer of example devices, and determining when skin temperature changes are environmentally or physiologically induced.

Provided are a computer device for fast stimulation artifact template-based real-time stimulation artifact removal and a method thereof. The computer device may be connected to a recording device in which data representing effect of stimulation on a living body is recorded and may be configured to generate a stimulation artifact template for the stimulation based on the recorded data, and to remove a stimulation artifact according to the stimulation from the recorded data using the stimulation artifact template.

Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.