The present disclosure provides an operation method of a PET (positron emission tomography) quantitative localization system, which includes steps as follows. The PET image and the MRI (magnetic resonance imaging) of the patient are acquired; the nonlinear deformation is performed on the MRI and the T1 template to generate deformation information parameters; the AAL (automated anatomical labeling) atlas is deformed to an individual brain space of the patient, so as to generate an individual brain space AAL atlas, where the AAL atlas and the T1 template are in a same space; lateralization indexes of the ROIs of the individual brain space AAL atlas corresponding to the PET image normalized through the gray-scale intensity are calculated; the lateralization indexes are inputted into one or more machine learning models to analyze the result of determining a target.

A circuit for receiving signals from a photodetector array arranged to detect signals generated by a crystal includes a plurality of summing circuits having weighting circuits, the summing circuits being configured to produce outputs corresponding to a total energy of the signals, a position of the signals in a first dimension of the photodetector array, a position of the signals in a second dimension of the photodetector array, and a radius of a charge distribution of the signals.

The present disclosure is related to removing scatter from a SPECT scan by utilizing a radiative transfer equation (RTE) method. An attenuation map and emission map are acquired for generating scatter sources maps and scatter on detectors using the RTE method. The estimated scatter on detectors can be removed to produce an image of a SPECT scan with less scatter. Both first-order and multiple-order scatter can be estimated and removed. Additionally, scatter caused by multiple tracers can be determined and removed.

An information processing method includes deducing a diagnosis name derived from a medical image on the basis of an image feature amount corresponding to a value indicating a feature of a medical image, deducing an image finding representing a feature of the medical image on the basis of the image feature amount, and presenting the image finding deduced in the deducing the image finding which is affected by an image feature amount common to the image feature amount that has affected the deduction of the diagnosis name in the deducing the diagnosis name and the diagnosis name to a user.

Parameterized model reconstruction is used for internal dose tomography. The parameterized model, solved for within the reconstruction, models the dose level and may account for diffusion, isotope half-life, and/or biological half-life. Using the detected emissions from different scans (e.g., from different scan sessions in a given cycle) as input for the one reconstruction, the parameterized model reconstruction determines the biodistribution of dose at any time.

Various methods and systems are provided for manufacturing a radiation shielding component of an imaging apparatus. In one embodiment, the radiation shielding component may be manufactured by infiltrating metal particles with a binder solution and then curing the binder solution impregnated with the metal particles. In another embodiment, the radiation shielding component may be printed with metal powder, infiltrated with a binding agent, and then cured to polymerize the binding agent.

An apparatus and method for reducing the blurriness of tomographic (3D) images constructed from a gamma camera system with one or more VASH (variable-angle slant-hole) collimators. A conventional gamma camera with a VASH collimator exhibits a loss of spatial resolution from the fact that the gamma-ray is entering the detector element at an angle other than normal to the surface. This depth dependence of the spatial localization causes a blurring of the spatial resolution, which is dependent on the incident angle relative to the normal, on the thickness of the detector element and on the stopping length of the gamma-ray in the detector element material. The invention provides an apparatus and method for correcting the spatial location where the gamma ray is recorded to improve the spatial resolution of the system.

Systems and techniques for reliably predicting a motion phase for non-invasive treatment of the heart. The system and methods may account for both respiratory and cardiac cycles in characterizing the motion of the heart relative to the irradiation source. The system and methods may also include a heartbeat sensor that provides an independent reference indication of the cardiac phase to provide real-time or near real-time quality assurance of a current predicted phase indication. The disclosed system and methods may be configured for use in one of two modes: “beam-gating” and “beam-tracking”. For beam-gating, the predicted cardiac phase is compared to the desired gating window, based on the patient-specific treatment plan, to determine if a gate ON or gate OFF signal should be set. For beam-tracking, the predicted cardiac phase is used to load the appropriate beam parameters based on the patient-specific and motion phase-dependent treatment plans.

The present disclosure provides methods of imaging cancerous cells in a subject, wherein the cancerous cells are localized to the skeletal system or central nervous system of the subject, the method comprising administering to the subject an effective amount of 18F-fluoroacetate, detecting a first signal emitted by 18F-fluoroacetate, and generating an image representative of the location and/or amount of the first signal to image the cancerous cells. In some embodiments, the methods further comprising diagnosing, prognosing, staging, and/or monitoring the progression of a disease or disorder, such as acute lymphoblastic leukemia and/or leptomeningeal disease.

Various methods and systems are provided for a power supply system. In one example, a method and system includes a power distribution unit (PDU) configured to receive power from a main power source and an uninterruptible power supply (UPS). The UPS includes a timer and the UPS is configured to directly power an output alternating current (AC) load after the main power source in unavailable. The UPS is also configured to power an output high voltage direct current (HVDC) load after the main power source is unavailable for a time delay measured by the timer.