A computer that determines at least an anatomic feature of a left atrial appendage (LAA) is described. During operation, the computer generates a 3D image associated with an individual's heart. This 3D image may present a view along a perpendicular direction to an opening of the LAA. Then, the computer may receive information specifying a set of reference locations. For example, the set of reference locations may include: a location on a circumflex artery, a location between a superior portion of the LAA and a left pulmonary vein, and/or a location on a superior wall of the LAA and distal to trabeculae carneae. Next, the computer automatically determines, based, at least in part, on the set of reference locations, at least the anatomical feature of the LAA, which is associated with the opening of the LAA and a size of a device used in an LAA closure (LAAC) procedure.

An imaging device and a method for generating a motion-compensated image or video are provided. The imaging device has a data acquisition facility for acquiring image data of a target object. The imaging device is configured to acquire, using a registration facility, a posture of an inertial measurement unit and, on the basis thereof, to carry out a registration between coordinate systems of the inertial measurement unit and the image data. The imaging device is further configured to acquire motion data from the inertial measurement unit arranged on the target object and, by processing the motion data, to generate the motion-compensated image or video.

Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements.

A method for vascular assessment is disclosed. The method, in some embodiments, comprises receiving a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processing the images to produce a stenotic model over the vasculature, the stenotic model having measurements of the vasculature at one or more locations along vessels of the vasculature. The method, in some embodiments, further comprises obtaining a flow characteristic of the stenotic model, and calculating an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.

Systems and methods for breast x-ray tomosynthesis that enhance spatial resolution in the direction in which the breast is flattened for examination. In addition to x-ray data acquisition of 2D projection tomosynthesis images ETp1 over a shorter source trajectory similar to known breast tomosynthesis, supplemental 2D images ETp2 are taken over a longer source trajectory and the two sets of projection images are processed into breast slice images ETr that exhibit enhanced spatial resolution, including in the thickness direction of the breast. Additional features include breast CT of an upright patient's flattened breast, multi-mode tomosynthesis, and shielding the patient from moving equipment.

A method and a corresponding system are provided. The method comprises steps of providing 2D images and subsequently detecting outlines of a primary structure in each of the images. A visual representation of the 2D images is generated and the 2D images are then arranged as 2D slices in a 3D visual representation. To this end, at least two of the 2D images are taken at different imaging angles. The method provides a 3D visual representation of a region of interest comprising a primary structure to support a spatial sense of a user.

The present disclosure provides a method for identifying sites for administering cells in cell therapy for central nervous system damage in a subject, comprising the steps of: A) acquiring image data on at least part of the subject's brain, with an imaging device; B) obtaining information on the subject's brain, with a computer device in communication with the imaging device; C) using the image data and data pertaining to the subject's brain acquired by the computer device to depict motor fibers; D) identifying damaged locations where motor fibers have suffered damage, with the computer device, identifying a portion where motor fiber run-data is lower than another portion and identifying the lower portion as being motor fibers that have suffered damage; E) using the computer device to select, as sites of administration, safe regions near the damaged locations; and F) outputting, as graphic display, the selected sites of administration.

A medical imaging system includes a movable station having a C-arm, a collector, an X-ray beam emitter, and a controller. The collector is attached to a first end of the C-arm. The X-ray beam emitter faces the collector to emit an X-ray beam in a direction of the collector and is attached to a second end of the C-arm. The controller moves one of the X-ray beam emitter and the collector to a first offset position along a lateral axis orthogonal to the arc, and obtains a first set of images by rotating the collector and the X-ray beam emitter along the arc about a scanned volume. The controller moves the one of the X-ray beam emitter and the collector to a second offset position along the lateral axis, and obtains a second set of images. The controller combines the first and second set of images to generate a three-dimensional image of the scanned volume.

Various methods and systems are provided for x-ray imaging. In one embodiment, a method includes acquiring a plurality of fluoroscopic images depicting an interventional tool positioned relative to an anatomy of interest of a patient, segmenting the interventional tool in the plurality of fluoroscopic images, measuring motion of the patient in the plurality of fluoroscopic images, correcting the plurality of fluoroscopic images to remove the motion of the patient, registering the segmented interventional tool to the anatomy of interest in the corrected plurality of fluoroscopic images, and displaying images with the segmented interventional tool registered to the anatomy of interest. In this way, a practitioner may view the position and movement of an interventional tool located within a patient relative to static images of the anatomy without motion artifacts or errors induced by patient motion such as respiratory motion or cardiac motion.

A method for geometric calibration of a volume imaging apparatus disposes calibration phantom in a radiation path that includes a subject positioned between an x-ray source and a detector. The phantom has a number of radio-opaque markers formed of a marker material. In a repeated sequence, at each of a number of positional relationships of the x-ray source to the detector: 2D projection image data is acquired for the subject and the phantom, wherein the 2D projection image data distinguishes at least first and second x-ray energy distributions; source-to-detector geometry of the imaging apparatus is calculated, corresponding to the acquired 2D projection image data for the first and second x-ray energy distributions. The method reconstructs and displays a 3D volume image of the subject according to acquired anatomy image data from the subject and source-to-detector geometry within the 2D projection images.