A method for evaluating one or more diagnostic linages of a patient obtained in different examination sessions and evaluating the diagnostic images using trained machine learning logic to generate prognosis and treatment information related to a medical condition of the patient detected during the evaluation. The prognosis-related information is recorded and displayed.

Systems and methods for performing an assessment of a lesion are provided. A plurality of input medical images of a lesion is received. The plurality of input medical images comprises an initial input medical image and one or more additional input medical images. The initial input medical image comprises a region of interest around the lesion. A mask of the lesion is curated for the initial input medical image based on the region of interest and a set of candidate masks. The region of interest in the initial input medical image is propagated to the one or more additional input medical images based on prior registration transformations. A mask of the lesion is curated for each of the one or more additional input medical images based on the propagated regions of interest and the set of candidate masks. One or more assessments of the lesion are performed based on the mask for the initial input medical image, the masks for the one or more additional input medical images, and prior assessments of lesions. Results of the one or more assessments of the lesion are output.

A radiomic biomarker determination method and system for assessment of the risk of metabolic diseases. The method includes: obtaining abdominal & pelvic volumetric computed tomography (CT) scan from the given subject; determining the fat area to be analyzed from the CT scan, separating visceral fat using an image segmentation method, and normalizing the visceral fat area under physical scale; extracting N imaging features of the visceral fat; selecting n optimal imaging features from the N candidate features; dividing the normalized visceral fat area into multiple visceral fat blocks with equal thickness; extracting n corresponding optimal imaging features from each visceral fat block, named as block imaging features; and determining the representative visceral fat block from the candidate blocks and taking the representative visceral fat block and the (block) imaging features extracted from the representative visceral fat block as radiomic biomarkers.

Systems and methods for automated assessment of a vessel are provided. One or more input medical images of a vessel of a patient are received. A plurality of vessel assessment tasks for assessing the vessel is performed using a machine learning based model trained using multi-task learning. The plurality of vessel assessment tasks comprises segmentation of reference walls of the vessel from the one or more input medical images and segmentation of lumen of the vessel from the one or more input medical images. Results of the plurality of vessel assessment tasks are output.

A computing system (118) includes a computer readable storage medium (122) with computer executable instructions (124), including a biophysical simulator (126) and an electrocardiogram signal analyzer (128). The computing system further includes a processor (120) configured to execute the electrocardiogram signal analyzer determine myocardial infarction characteristics from an input electrocardiogram and to execute the biophysical simulator to simulate a fractional flow reserve or an instant wave-free ratio index from input cardiac image data and the determined myocardial infarction characteristics.

At least one vascular tree supplying at least a part of the hollow organ in the computed tomography dataset is segmented, and a tree structure up to an order possible based on the blood vessel segmentation result is determined from a blood vessel segmentation result. Perfusion information for each edge in the tree structure is assigned as at least one of the computed tomography data assigned to the blood vessel segment or at least one value derived therefrom. Adjacent hollow organ segments of the hollow organ are defined based on supply by adjacent blood vessels in the tree structure, and the tree structure and the perfusion information are analyzed to determine hemodynamic information to assign to hollow organ segments. At least a part of the hemodynamic information in at least one of the computed tomography dataset or a visualization dataset derived therefrom is then visualized.

An invention is described herein in which the current subjective decisions to perform a percutaneous coronary intervention (PCI, i.e., “coronary stenting”) for coronary artery disease (CAD) is replaced with consistent and objective algorithm-driven decision trees based on the results of recent clinical trials and studies and objective analysis of the coronary angiogram. This should result in reduced risk and medical cost for patients.

Disclosed herein is a method, comprising: causing emission of characteristic X-rays of a chemical element in an object by directing radiation to the object; capturing images of the object using the radiation that has transmitted through the object; capturing images of the chemical element in the object using the characteristic X-rays; reconstructing a three-dimensional image of the object based on the images of the object; determining a three-dimensional distribution of the chemical element in the object based on the images of the chemical element; and superposing the three-dimensional image of the object and the three-dimensional distribution of the chemical element in the object to form a superposed image of the object. The radiation directed to the object comes from multiple radiation sources. The images are captured with multiple image sensors. The radiation sources and the image sensors are stationary with respect to the object.

An image processing apparatus includes at least one processor. The processor is configured to execute calcification image detection processing of detecting a calcification image based on a plurality of tomographic images obtained from a series of a plurality of projection images obtained by tomosynthesis imaging of a breast, region-of-interest image group generation processing of generating a region-of-interest image group by cutting out, as a region-of-interest image, a region including the calcification image detected by the calcification image detection processing from each of the plurality of projection images, variance value calculation processing of calculating a variance value of feature amounts of each of the region-of-interest images included in the region-of-interest image group, and shape type determination processing of determining a type of a shape of the calcification image based on the variance value calculated by the variance value calculation processing.

An image processing apparatus includes at least one processor. The processor is configured to execute region-of-interest image generation processing of generating a region-of-interest image from a projection image, which is obtained at an irradiation position closest to a position facing a detection surface of a radiation detector, among a series of projection images obtained by irradiating a breast with radiations and imaging the breast, and shape type determination processing of determining a type of a shape of a calcification image included in the region-of-interest image generated by the region-of-interest image generation processing.