Among other things, one or more techniques and/or systems for calibration of a radiation system to compute a gain correction(s) are provided. A calibration procedure is performed during which a portion of the detector array is shadowed by an object, causing the detector array to be non-uniformly exposed to radiation. A portion of a projection generated from the calibration procedure and indicative of radiation that did not traverse the object is separated from a portion of the projection indicative of radiation that did traverse the object, and a gain correction(s) is computed from the portion of the projection indicative of radiation that did not traverse the object (e.g., and is thus indicative of radiation that merely traversed air).

The present disclosure directs to a system and method for image processing. The method for image processing comprises acquiring a plurality of original computed tomography (CT) images of a spine of a subject; generating CT value images of the spine of the subject by processing the plurality of original CT images. The method further includes identifying an optimal sagittal image in which a centerline of the spine is located based on the CT value images. The method further includes identifying the centerline of the spine within the optimal sagittal image. The method further includes identifying a center point and a direction of at least one intervertebral disc along the centerline of the spine. The method still further includes reconstructing an image of the at least one intervertebral disc based on the center point and the direction of the at least one intervertebral disc.

Computerized methods and systems for estimating a dual-energy X-ray absorptiometry (DEXA) score from CT imaging data by receiving imaging data of a computed tomography (CT) scan of a body of a patient containing at least a bone portion, segmenting the bone portion from the imaging data , computing at least one grade based on pixel associated values from the bone portion, and correlating the at least one grade with at least one score representing a relation to bone density values in a population obtained based on a DEXA scan. The grade is computed from a calculation of sub-grades performed for each one or a set of pixels having at least one of a common medial-lateral axial coordinate and a common cranial-caudal axial coordinate along a dorsal-ventral axis of a volume representation of the imaging data.

A medical imaging system (200) includes a masking unit (234), an image registration unit (238), a motion estimator (240) and a motion compensating reconstructor (244). The masking unit constructs a mask for each reconstructed volumetric phase image of a plurality of reconstructed volumetric phase images that masks portions of a corresponding image external to an anatomical model fitted to a segmented at least one anatomical structure, 5 wherein the plurality of reconstructed volumetric phase images include a target phase and a plurality of temporal neighboring phases reconstructed from projection data. The image registration unit registers the masked reconstructed volumetric phase images. The motion estimator estimates motion between the target phase and the plurality of temporal neighboring phases according to the model based on the registered masked reconstructed 10 volumetric phase images. The motion compensating reconstructor reconstructs a motion compensated medical image from the projection data using the estimated motion of the registered masked reconstructed volumetric phase images.

A three-dimensional subtraction angiography image data set including a target region of the patient is acquired. A region of interest is selected. An imaging geometry is defined for monitoring the intervention using an X-ray device. The image-obscuring blood vessels that superimpose the region of interest in the imaging geometry and imaging zones that show fractions of the image-obscuring blood vessels in the imaging geometry are determined. Path information relating to the image-obscuring blood vessels is defined. The information relating to the path is input into a two-dimensional forward projection data set. A fluoroscopic image is acquired in the imaging geometry. Pixels showing the image-obscuring blood vessels in the fluoroscopic image are determined using the path information and image intensity information from the fluoroscopic image. A masked image of the image-obscuring blood vessels is subtracted. The fluoroscopic image that has been modified is displayed.

Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.

In at least one embodiment, X-ray images of a human examination object acquired via X-ray equipment are each spatially-resolved in a plurality of dimensions. In each case, one dimension extends in the head-foot direction of the examination object. The respective body region is detected in the X-ray images in steps that are equidistant in the head-foot direction and, based on this, the water-equivalent diameter of the examination object is determined in a plane orthogonal to the head-foot direction. The water equivalent diameters determined for each respective position is stored with allocation to the X-ray images and the respective position in the head-foot direction.

A method for generating x-ray images of an examination object is described. In the method, x-rays are emitted in a direction of an x-ray detector, wherein an examination object is arranged between the x-ray detector and an x-ray source emitting the x-rays. An anti-scatter grid, which is arranged between the examination object and the x-ray detector, is moved across the detection surface of the x-ray detector. X-ray detector signals are acquired with temporal and spatial resolution, the x-ray detector signals including the intensity of the x-rays incident on the x-ray detector. The x-ray detector signals are evaluated taking into account a temporal variation of the acquired intensity of the x-ray detector signals caused by the movement of the anti-scatter grid. An x-ray imaging apparatus is also described.

The X-ray imaging apparatus is provided with an X-ray source, a plurality of gratings including a first grating and a second grating, a detector, a rotation mechanism for relatively rotating a subject including a fiber bundle and an imaging system, and an image processor for generating a dark field image. The image processor is configured to obtain a three-dimensional dark field image of the subject including at least the fiber bundle from a plurality of dark field images captured at a plurality of rotation angles.

Among other things, one or more techniques and/or systems for calibration of a radiation system to compute a gain correction(s) are provided. A calibration procedure is performed during which a portion of the detector array is shadowed by an object, causing the detector array to be non-uniformly exposed to radiation. A portion of a projection generated from the calibration procedure and indicative of radiation that did not traverse the object is separated from a portion of the projection indicative of radiation that did traverse the object, and a gain correction(s) is computed from the portion of the projection indicative of radiation that did not traverse the object (e.g., and is thus indicative of radiation that merely traversed air).