The present invention relates to a pose estimation method of an interventional medical device using a single-view X-ray image which is captured using a bendable interventional medical device equipped with a plurality of radiopaque markers and using an X-ray source. The pose estimation method includes an operation (a) of defining a circle assuming that the interventional medical device is bent at a constant curvature, an operation (b) of extracting a position value of the marker from an X-ray image obtained by the X-ray source projecting X-rays onto the markers, and an operation (c) of setting a projection plane and estimating a shape of the circle using a position value of the marker extracted from a projected image obtained by perspective-projecting the circle onto the projection plane and using the position value of the marker extracted from the X-ray image.

According to some aspects, a carrier configured for use with a broadband x-ray source comprising an electron source and a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target is provided. The carrier comprising a housing configured to be removeably coupled to the broadband x-ray source and configured to accommodate a secondary target capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation, the housing comprising a transmissive portion configured to allow broadband x-ray radiation to be transmitted to the secondary target when present, and a blocking portion configured to absorb broadband x-ray radiation.

An apparatus and method for imaging quality assessment of an imaging system employs an aggregate phantom and a processor for imaging analysis. The aggregate phantom includes a plurality of self-contained sections configured to be moved independently and re-assembled in the imaging system. Each section includes fiducial features of known relative location. The processor: quantitatively determines location of the fiducial features within an image of the aggregate phantom; compares the determined location within the image to the known relative location of the fiducial features to produce a distortion field; and distinguishes between actual geometric distortion of the imaging system and rigid-body transformations of sections of the aggregate phantom, in the distortion field. For extended fields-of-view, the aggregate phantom may be repositioned, and sets of images combined to determine a distortion field of the extended image. A method employing virtual features for measuring spatial uniformity of an acquired signal, is also provided.

A method and an apparatus for estimating a geometric thickness of a breast in mammography/tomosynthesis or in other x-ray procedures, by imaging markers that are in the path of x-rays passing through the imaged object. The markings can be selected to be visible or to be invisible when the composite markings/breast image is viewed in clinical settings. If desired, the contribution of the markers to the image can be removed through further processing. The resulting information can be used determining the geometric thickness of the body being x-rayed and thus setting imaging parameters that are thickness-related, and for other purposes. The method and apparatus also have application in other types of x-ray imaging.

Disclosed are a radiotherapy system and a treatment plan generation method therefor. The radiotherapy system includes a beam irradiation device, a treatment planning module and a control module. The beam irradiation device generates a beam for treatment and irradiates same to a body to be irradiated to form an irradiated site, the treatment planning module generates a treatment plan on the basis of parameters of the beam for treatment and medical image data of the irradiated site, and the control module retrieves a treatment plan corresponding to said body from the treatment planning module and controls the beam irradiation device to sequentially irradiate said body according to at least two irradiation angles determined according to the treatment plan generation method and the irradiation time corresponding to each irradiation angle.

A detector sub-assembly for a CT system includes a detector module that includes a mount block having a top planar surface, a Y-axis planar surface that is parallel with the top planar surface, an X-axis planar surface that is orthogonal to the first Y-axis planar surface, and an aperture passing through the X-axis planar surface. The module includes a substrate having a pixelated photodiode positioned thereon, and a two-dimensional anti-scatter grid (ASG) positioned on the pixelated photodiode. The detector sub-assembly includes a support structure including a Y-axis mount surface and an X-axis mount surface, and a second aperture passing through the X-axis mount surface, a mounting screw having an outer diameter that is smaller than an inner diameter of the aperture and passing through the aperture and into the second aperture when the Y-axis planar surface is on the Y-axis mount surface.

The present invention relates to an apparatus (10) for processing of data acquired by a dark-field and/or phase contrast X-ray imaging system, the apparatus comprising an input unit (20), and a processing unit (30). The input unit is configured to provide the processing unit with blank scan fringe data acquired by a dark-field and/or phase contrast X-ray imaging system comprising an interferometry arrangement and detector. The input unit is configured to provide the processing unit with sample scan fringe data acquired by the dark-field and/or phase contrast X-ray imaging system, with an object to be imaged is positioned within the dark-field and/or phase contrast X-ray imaging system. The processing unit is configured to pre-process the blank scan fringe data to determine pre- processed blank scan fringe data comprising utilization of an effective point spread function “PSF”. The processing unit is configured to pre-process the sample scan fringe data to determine pre- processed sample scan fringe data, comprising utilization of the effective point spread function “PSF”. The effective PSF has been determined for the dark-field and/ or phase contrast X-ray imaging system.

A phantom, calibration system and calibration method are described. The phantom having a phantom body and an X-ray luminescent material, wherein at least a portion of the X-ray luminescent material is on a surface of the phantom.

Embodiments provide a modular phantom that enables quantitative assessment of imaging performance (e.g., spatial resolution, image uniformity, image noise, contrast to noise ratio, cone-beam artifact) and dosimetry in cone-beam computed tomography (CT). The modular phantom includes one or more modules for various imaging performance tests that may be rearranged in the phantom to accommodate the design of various cone-beam CT imaging systems. The modular phantom includes one or more of a cone-beam module, an angled edge module, or a line spread module. The phantom may be inserted into a larger sleeve and be used to assess imaging performance and dosimetry in whole body CT imaging systems.

For calibration of internal dose in nuclear imaging, the dose model used for estimating internal dose in a patient is calibrated. One or more values of the dose model (e.g., a physics simulation, dose kernels, or a transport model) are set based on measured dose. The dose may be measured relative to specific tissues and/or isotopes, providing for tracer and tissue specific calibration. For example, dose from the tracer to be injected into the patient is estimated from emissions as well as measured by a dosimeter in a tissue mimicking tissue mimicking object. These doses are used to calibrate the dose model, which calibrated dose model is then used to determine internal dose for the patient.