The proposed technology relates to a method for indicating a risk for coronary artery disease. A sound recording is obtained (100) covering a plurality of heartbeats, a plurality of heart sounds are identified (200) in the sound recording, and a plurality of segments are obtained (300) from the sound recording. A frequency power measure is determined (400) based on the signal strength of a first frequency window of a period in the diastole, an amplitude of the fourth heart sound is determined (500) based on the plurality of heart sounds and the plurality of segments, and an indication of a heart rate variability is determined (600) based on the plurality of heart sounds. The indication of the risk for coronary artery disease is then determined (700) based on the frequency power measure, the amplitude of the fourth heart sound, and the indication of the heart rate variability.

A blood pressure cuff may comprise an alignment component, a sleeve, and a tapered inflatable bladder disposed within the sleeve. The tapered inflatable bladder may have a width that increases as the distance from the alignment component increases, and the tapered inflatable bladder and the alignment component may be configured to position the blood pressure cuff around a limb having a blood vessel and a circumference, such that at a position coincident with the blood vessel, the width of the tapered inflatable bladder is about 40% of the circumference of the limb. A method of using such a blood pressure cuff may comprise placing the alignment component at the position coincident with the blood vessel of the limb, wrapping the cuff around the limb such that the width of the tapered inflatable bladder overlaying the blood vessel is about 40% of the circumference of the limb, and inflating the bladder.

A device is configured for tracking e.g. the diastolic blood pressure in a patient. The device applies a pressure to a body part, e.g. by use of an inflatable cuff. By performing repeated and alternating pressure changes in the cuff, a specific feature of a signal that relates to the diastolic blood pressure can be tracked and possibly measured. The device may have particular use in conjunction with cardiopulmonary resuscitation devices.

In one embodiment, a system for determining physiological parameters from blood flow dynamics includes a catheter configured for insertion into a blood vessel of a subject through which blood flows, a flexible barrier associated with the catheter configured to oscillate in response to changes in pressure of the blood within the catheter, and a pressure field microphone configured to measure a pressure field induced by the oscillation of the flexible barrier and to generate a measured acoustic pressure signal that can be processed to determine the physiological parameters.

Example blood pressure apparatus using active materials and related methods are described herein. An example apparatus includes a band to be worn around a limb of a user, an active material carried by the band and a controller to: (1) apply an activation signal to the active material to constrict blood flow in the limb, and (2) reduce the activation signal to allow blood flow in the limb.

Systems, devices, and methods for monitoring and assessing blood glucose level in a patient are discussed. An exemplary system receives physiologic information from a patient using an ambulatory medical device. The physiologic information is correlated to, and different from, a direct glucose level measurement. The system determines a glucose index indicative of an abnormal blood glucose level using the received physiologic information by the two or more physiologic sensors. The system may use the glucose index to initiate or adjust a therapy, or to trigger a glucose sensor, separate from the two or more physiologic sensors, to directly measure blood glucose concentration.

The present disclosure relates to a method, an apparatus and a computer program for noninvasively determining a cause of a blood pressure change. The method includes at least: obtaining maximum amplitudes of heart sounds; monitoring changes in the maximum amplitudes; estimating change amounts of indexes on a myocardial contractile force and on vascular resistance, based on increasing or decreasing of a blood pressure of the patient, and the changes in the maximum amplitudes; and determining the cause of the blood pressure change of the patient as an effect of at least one of alpha action, alpha blockage, beta action and beta blockage, based on results of the estimation of the first change amount of the first index, the second change amount of the second index and the third change amount of the third index.

A system includes one or more sensors to detect activities of a mobile object; and a processor coupled to the sensor and the wireless transceiver to classify sequences of motions into groups of similar postures each represented by a model and to apply the models to identify an activity of the object.

A monitoring system a user activity sensor to determine patterns of activity based upon the user activity occurring over time.

A monitoring system using an activity sensor to determine patterns of activity based upon the user activity occurring over time.