Multifunctional ultrasound systems and methods for body section registration and mapping of microbubble dynamics. A system is provided that includes one or more micromachined ultrasonic transducer arrays (MUTAs) configured to capture a high-resolution image of at least a portion of a body section using ultrasound and monitor microbubble activity during ultrasound treatment. The system includes an image registration module configured to spatially register the high-resolution image with a reference image. The system includes electronics configured to control one or more of drive signal amplitude, frequency filtering, multiplexing, and DC bias voltage. The system can be configured to control ultrasound treatment based on the monitoring of the microbubble activity during treatment.

Aspects of the technology described herein relate to wirelessly offloading, from a wearable ultrasound device, ultrasound data sufficient for forming one or more ultrasound images therefrom. The wearable ultrasound device may include an ultrasound patch. Indications that may be monitored with such a device, and therapeutic uses that may be provided by such a device, are also described. Methods and apparatuses are also described for compounding multilines of ultrasound data on an ultrasound device configured to collect the ultrasound data. Additionally, certain aspects of the technology relate to non-uniform grouping of ultrasound transducers that share a transmit/receive circuit in an ultrasound device.

In one embodiment a system includes a ultrasound probe to capture 2D ultrasonic images of a body part of a living subject, a process to generate a 3D anatomical map of the body part, the 3D anatomical map and the 2D ultrasonic images being registered with a 3D coordinate space, add a 3D indication of an anatomical structure to the 3D anatomical map, render to a display the 3D anatomical map including the 3D indication of the anatomical structure, and render to the display a given one of the 2D ultrasonic images with a 2D indication of the anatomical structure on the given 2D ultrasonic image responsively to the 3D indication of the anatomical structure.

In some embodiments, an apparatus and methods for inserting a needle into a patient is disclosed. An apparatus can include a base having a cavity for receiving an ultrasound probe, a swing arm, a first linear position sensing track, a second linear position sensing track, an angle sensor disposed about a pivot point, a needle holder configured to move along the first linear position sensing track, and an insertion depth slider configured to move along the second linear position sensing track.

A system and related methods for performing nerve detection during surgical access using ultrasound testing during surgery.

Methods and apparatuses for performing automated detection of lung slide using a computing device (e.g., an ultrasound system, etc.) are disclosed. In some embodiments, the techniques determine lung sliding using one or more neural networks. In some embodiments, the neural networks are part of a process that determines probabilities of the lung sliding at one or more M-lines. In some embodiments, the techniques display one or more probabilities of lung sliding in a B-mode ultrasound image.

The present disclosure describes ultrasound systems and methods configured to determine the elasticity of a target tissue. Systems can include an ultrasound transducer configured to acquire echoes responsive to ultrasound pulses transmitted toward the tissue, which may include a region of increased stiffness. Systems can also include a beamformer configured to control the transducer to transmit a push pulse into the tissue, thereby generating a shear wave in the region of increased stiffness. The beamformer can be configured to control the transducer to emit tracking pulses adjacent to the push pulse. Systems can further include a processor configured to determine a displacement amplitude of the shear wave and based on the amplitude, generate a qualitative tissue elasticity map of the tissue. The processor can combine the qualitative map with a quantitative map of the same tissue, and based on the combination, determine a boundary of the region of increased stiffness.

Cancer treatment methods using thermotherapy and/or enhanced immunotherapy are disclosed herein. In one embodiment, the method comprising the steps of: (i) applying controlled thermal energy at 40-43° C. for a first predetermined time period to damage and weaken tumor cells of a tumor in a patient; (ii) administering pulsed high intensity focused ultrasound (pHIFU) in a first ultrasound mode to the tumor cells in the patient so as to damage the tumor cells without increasing the thermal energy; and (iii) administering low intensity focused ultrasound (LIFU) in a second ultrasound mode to further damage the tumor cells at a temperature of 39-43° C. for a second predetermined time period while performing observation of the tumor cells by ultrasonic thermometry.

Embodiments of the disclosure include a tissue and/or access device that allows for adjustability of placement of a needle for accessing a blood vessel of an individual in need thereof, particularly when used with an imaging device. The adjustability originates from both angle of the needle for insertion into the body of the individual and longitudinal placement of the needle on the body of the individual. In specific embodiments, a needle guide through which the needle traverses is detachable.

An intraoperative ultrasound imaging system and method capable of using ultrasound imaging to safely place a surgical access instrument (e.g. guide wire, dilator, cannula, etc.) through a tissue (e.g., muscle, fat, brain, liver, lung, etc.) without damaging nearby neurovascular structure is described herein. The intraoperative ultrasound system includes an ultrasound probe assembly configured for emitting and receiving ultrasound waves and a computer system including a processor and a display unit. Once the probe is in position, ultrasound imaging is performed wherein the computer receives RF data from the probe and causes a B-mode image of the visible anatomical structures (e.g. muscle, bone, etc.) to be displayed on the display unit.