Among the various aspects of the present disclosure is the provision of a noninvasive and localized brain liquid biopsy using focused ultrasound. Briefly, therefore, the present disclosure is directed to methods and systems to identify brain lesion or tumor characteristics without the need for a solid brain biopsy.

The tissue removal device using focused ultrasound includes a focused ultrasound output unit, a mode setting unit to set an output mode of the focused ultrasound, and a control unit to control output characteristics of the focused ultrasound according to the set mode, wherein the output mode is selected from a first mode for removing a tissue in a local area using a vapor bubble formed by the focused ultrasound, a second mode for removing a tissue in a narrower area than the first mode by controlling the output characteristics of the focused ultrasound immediately after the vapor bubble is formed by the focused ultrasound, and a third mode for obtaining a skin tightening effect by generating heating in a subcutaneous fat layer using focused ultrasound of lower intensity and a longer pulse length than the first mode and the second mode.

The present disclosure discloses a method and an apparatus for acquiring motion information. A frequency domain transformation is performed on a detection signal of a vibration propagating in a medium to obtain a frequency domain signal, then a signal that is outside of a defined vibration velocity range is removed from the frequency domain signal, that is, only a vibration signal is retained, and then a position-time diagram is obtained along a defined vibration propagation direction. It is not necessary to perform motion estimation on propagation of the vibration by a complicated calculation, and it is only necessary to determine the presence or absence of the vibration by processing in the frequency domain, and then the position-time diagram is obtained, which is a highly efficient method for acquiring motion information.

There is provided a tissue elasticity measurement device 100 and a measurement method that allow for quantitative evaluation of biological changes related to tissue elasticity such as liver fibrosis. The tissue elasticity measurement device 100 has a supersonic wave measuring instrument 100a that measures a pulse waveform corresponding to a blood flow velocity by a pulse wave Doppler method, and an information processor 100b that calculates a deviation index value corresponding to a coefficient of variation from a pulse waveform obtained by the supersonic wave measuring instrument 100a.

A biopsy device includes an elongated handle body having a proximal end portion and a distal end portion, a needle disposed within the handle body, first and second transducers, and a display. The needle is configured to move between a retracted position and a deployed position. The first and second ultrasound transducers are disposed within the distal end portion of the handle body. The first and second ultrasound transducers are angled relative to one another and define a space therebetween configured for passage of the needle.

A system and method for presenting rotation previews of an object depicted in a volume rendering of 3D and/or 4D image data is provided. The method includes presenting a volume rendering of an object having an initial view at a display system. The method includes presenting volume rendering previews at the display system. Each of the volume rendering previews provides a different rotational view of the object and is located on the display system in relation to the volume rendering at a position associated with a directional directive of a user input device. The method includes receiving a directional directive from the user input device. The method includes presenting an updated volume rendering of the object at the display system. The updated volume rendering includes an updated view of the object rotated from the initial view based on the directional directive from the user input device.

A system for detecting a position of a long medical device includes a model acquisition portion that acquires a blood vessel model, a correspondence detection portion 1 that detects a position of a long medical device inserted into a blood vessel and detects a correspondence between the blood vessel model and the position of the long medical device, and a display portion that displays the position of the long medical device in association with the blood vessel model on the basis of a detection result of the correspondence detection portion.

An ultrasound diagnostic apparatus (1) includes a urinary bladder extraction unit (9), a feature quantity calculation unit (10), a failed frame determination unit (16), a rescan determination unit (17), a rescan recommendation unit (19), a measurement frame selection unit (12), and a urine volume measurement unit (13). The urinary bladder extraction unit (9) extracts a urinary bladder region from an ultrasound image. The feature quantity calculation unit (10) calculates a feature quantity of the urinary bladder region. The failed frame determination unit (16) determines whether the ultrasound image is of a failed frame for which a scan with an ultrasonic beam has failed. The rescan determination unit (17) determines whether a rescan with an ultrasonic beam is needed based on a time-series change in the feature quantity and a time-series position of the failed frame. The rescan recommendation unit (19) recommends the rescan with the ultrasonic beam to the user if the rescan with the ultrasonic beam is determined to be needed. The measurement frame selection unit (12) selects an ultrasound image of a measurement frame based on the feature quantity. The urine volume measurement unit (13) analyzes the ultrasound image of the measurement frame to measure a urine volume.

An image analyzer unit performs lesion site detection for each tomographic image. In response to a lesion site detection state, the image analyzer unit outputs a position data array and a size data array that represent temporal change in position and size of the lesion site. A rate of change calculator unit calculates a rate of change that represents a degree of temporal change in tomographic image content. A smoother unit smooths the position data array and the size data array in accordance with the rate of change. A mark is generated based on the smoothed position data array and the smoothed size data array.

Systems and methods for tracking a target volume, e.g., tumor, in real-time during radiation treatment are provided. The system includes a memory to store a pre-acquired 3D image of the anatomy of interest in a first reference frame and a processor, operative coupled with the memory, to receive, from an ultrasound probe, a set-up ultrasound image of the anatomy of interest in a second reference frame. The processor further to establish a transformation between the first and second reference frames by registering the set-up ultrasound image with the pre-acquired 3D image and receive, from the ultrasound probe, an intrafraction ultrasound image of the anatomy of interest. The processor further to register the intrafraction ultrasound image with the set-up ultrasound image and track motion of the anatomy of interest based on the registered intrafraction ultrasound image.