A device is for estimating the central blood pressure of a subject. The device comprises a sensor patch comprising an array of sensors configured to measure an indication of the blood pressure of a peripheral blood vessel and perform ultrasound imaging of the peripheral blood vessel. The device also comprises a processor configured to obtain a peripheral pressure signal comprising a pressure waveform from the indication of the blood pressure from the sensor patch and derive an image of the peripheral blood vessel from the signals received from the sensor patch. A vessel diameter is determined from the image of the peripheral blood vessel over time comprising a vessel diameter waveform and an estimate of the central blood pressure of the subject is derived from the pressure waveform and/or the vessel diameter waveform.

Systems and methods for stroke detection in accordance with embodiments of the invention are illustrated. One embodiment includes a system for detecting strokes, including a processor, a first ultrasound transmitter located on a patient's head in communication with the processor, a first ultrasound receiver located on the patient's head in communication with the processor, a memory in communication with the processor, including a stroke diagnostics application, where the stroke diagnostics application directs the processor to transmit a first ultrasound signal from the first ultrasound transmitter across a patient's brain, the brain comprising a first and second hemisphere, receive the first ultrasound signal using the first ultrasound receiver, where the ultrasound signal is affected during transit by harmonics generated by microbubbles in the blood of the patient stimulated by the first ultrasound signal, and detect that a stroke has occurred based on the harmonic effects on the first received ultrasound signal.

The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, adjustable positioning structures are described that allow a general probe positioning structure to be configured for a specific patient in a manner that allows the device to be used repeatedly to target the anatomic region, even when in non-clinical settings. In other aspects, a probe positioning structure is fabricated that is specific to a respective patient anatomy, such that use of the probe positioning structure provides repeatable targeting of the target anatomic region, even when in non-clinical settings.

A radial compression band is configured to provide hemostatic compression to an arterial access site on the arm of a wearer. The radial compression band includes an elongated arm band that presents an arm opening sized to receive the arm. The arm band presents proximal and distal margins, with the arm opening being defined between the margins.

A wearable, open and adjustable MRI head coil system having an assembly of support members, panels, or portions defining one or more access openings. The support members, panels, or portions can support, house, or otherwise include radiofrequency receiver antennae or imaging coils such that the assembly is positionable or wearable by a patient for MRI scanning. The radiofrequency receiver antennae or imaging coils, and other devices can be simultaneously in contact with a patient's head, thereby enabling use during diagnostic, therapeutic, surgical or other interventional procedures.

A system for monitoring blood flow in a patient, the system comprising: a single-element disc-shaped ultrasound transducer for fastening to the patient and a controller subsystem. The controller subsystem is configured to: control the ultrasound transducer to transmit a series of plane-wave pulses into the patient in a propagation direction; sample reflections of the plane-wave pulses, received at the ultrasound transducer, from a region within the patient, to generate pulse-Doppler response signals; and process the pulse-Doppler response signals to calculate a blood flow curve for waveform analysis.

A computer-implemented method of identifying a subject's body part on which a hand-held device is used to perform a personal care operation. The hand-held device comprises a head portion for contacting the subject's skin one or more sensors for measuring a parameter and generating measurement signals as the hand-held device is used on the subject's skin. The sensor(s) comprise(s) at least one of a skin contact sensor, skin tone sensor, and/or proximity sensor. The method includes obtaining a measurement signal from each sensor; analyzing the obtained measurement signal using a trained machine learning model (MLM) to identify the subject's body part that the hand-held device is used on. The trained MLM analyzes a plurality of measurements in a time window on each of the obtained measurement signals to identify the body part. An indication of the identified body part is then outputted.

Systems and methods for determining position and orientation of a bone of an anatomical feature are described. These include the use of a wearable holder configured to be mounted about an outer-skin surface of the anatomical feature, such that the anatomical feature and the bone are positioned in fixed relation with respect to the wearable holder when the wearable holder is mounted about the anatomical feature. Reference marker arrays are fixedly mounted to the wearable holder, each being positioned on the wearable holder to identify a landmark of the bone within the wearable holder when the wearable holder is mounted to the anatomical feature. The position and orientation of the reference markers are trackable to determine position and orientation of the wearable holder in a reference coordinate system, thereby enabling position and orientation of the landmarks on the bone to be determined.

Improved imaging devices and methods. A portable SPECT imaging device may co-register with imaging modalities such as ultrasound. Gamma camera panels including gamma camera sensors may be connected to a mechanical arm. A coded aperture mask may be placed in front of a gamma-ray photon sensor and used to construct a high-resolution three-dimensional map of radioisotope distributions inside a patient, which can be generated by scanning the patient from a reduced range of directions around the patient and with radiation sensors placed in close proximity to this patient. Increased imaging sensitivity and resolution is provided. The SPECT imaging device can be used to guide medical interventions, such as biopsies and ablation therapies, and can also be used to guide surgeries.

A method for diagnosing a joint condition includes in one embodiment: creating a 3d model of the patient specific bone; registering the patient's bone with the bone model; tracking the motion of the patient specific bone through a range of motion; selecting a database including empirical mathematical descriptions of the motion of a plurality actual bones through ranges of motion; and comparing the motion of the patient specific bone to the database.