Gas vesicles, protein variants and related compositions methods and systems for singleplexed and/or multiplexed ultrasound imaging of a target site in which a gas vesicle provides contrast for the imaging which is modifiable by application of a selectable acoustic collapse pressure value of the gas vesicle.

Aspects of the technology described herein relate to determining, by a processing device in operative communication with an ultrasound device, a position and/or orientation of the ultrasound device relative to the processing device, and displaying on a display screen of the processing device, based on the position and/or orientation of the ultrasound device relative to the processing device, an instruction for moving the ultrasound device.

A cryosurgical system including a computer system programmed with software configured to perform the following steps: a) capturing at least one first view of a region of interest in a human body; b) capturing at least one second view of the region of interest; c) outlining the region of interest and at least one area outside the region of interest with the assistance of an operator; d) constructing a 3-dimensional model of the region of interest and the at least one area outside the region of interest utilizing the at least one first view and the at least one second view of the region of interest; and e) utilizing the 3-dimensional model of the region of interest and the at least one area outside the region of interest to determine at least one cryosurgical probe placement location.

An ultrasound diagnostic apparatus 1 includes a bladder pattern storage unit 22, a reference pattern setting unit 21, a bladder extraction unit 18 that extracts a bladder region from an ultrasound image, a bladder extraction success/failure determination unit 19 that determines whether the bladder region represents a bladder having the reference pattern, and an image quality adjustment unit 20 that adjusts the image quality of the ultrasound image in a case where determination is made that the bladder region does not represent the bladder having the reference pattern, in which in a case where the determination is made that the bladder region does not represent the bladder having the reference pattern even in an ultrasound image of which the image quality is adjusted, the bladder extraction success/failure determination unit 19 determines whether the bladder region represents the bladder having the abnormal bladder pattern.

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to an assembly with an adjustable ultrasound port and flush port for lateral and axial positioning of a radial ultrasound probe within a patient.

An ultrasound diagnosis apparatus includes: a scan controlling unit that exercises control to perform a first scanning process by transmitting an ultrasound wave in a first direction and a second scanning process by transmitting an ultrasound wave in each of a plurality of directions; an image generating unit that generates a first ultrasound image and second ultrasound images from the first and the second scanning processes, respectively; an image generation controlling unit that has a needle image generated, based on an analysis result on the brightness distribution of each member of a group of images based on the first ultrasound image and the second ultrasound images or an analysis result on the brightness distribution of each of the second ultrasound images; an image synthesizing unit that generates a synthesized image from the first ultrasound image and the needle image; and a display controlling unit that displays the synthesized image.

Therapeutic ultrasound devices and methods are provided. In one embodiment, a therapeutic ultrasound device includes a housing configured for handheld operation by a user, an ultrasound assembly positioned within the housing and configured to generate ultrasound energy, a battery positioned in the housing and coupled to the ultrasound assembly to power the ultrasound assembly to generate the ultrasound energy, a flexible elongate member configured to be positioned within a body lumen of a patient, and an acoustic transmission member. The flexible elongate member includes a proximal portion, a distal portion, and a first lumen extending between the proximal portion and the distal portion. The housing is coupled to the proximal portion. The acoustic transmission member includes a proximal portion acoustically coupled to the ultrasound assembly and configured to receive the ultrasound energy, and a distal portion extending within the first lumen and configured to transmit the ultrasound energy to the body lumen to deliver a therapy.

A system for providing integrated guidance for positioning a biopsy device and estimating tumor size in a body has two levels of guidance: a coarse guidance and a fine guidance. The system includes a non-invasive imaging system for obtaining an image of the biopsy device in the body, for providing the coarse guidance. Furthermore, the system includes an optical element mounted on the needle for obtaining optical information discriminating tissue in the body, for providing the fine guidance.

A method for diagnosing a joint condition includes in one embodiment: creating a 3d model of the patient specific bone; registering the patient's bone with the bone model; tracking the motion of the patient specific bone through a range of motion; selecting a database including empirical mathematical descriptions of the motion of a plurality actual bones through ranges of motion; and comparing the motion of the patient specific bone to the database.

This disclosure provides alternative medical imaging systems and methods for vascular imaging co-registration. Methods include obtaining extravascular imaging data of a portion of a blood vessel including an extravascular image showing an intravascular imaging device disposed within the vessel with an imaging element disposed at a starting location for a translation procedure. The extravascular image also includes an extravascular contrast image showing the portion of the blood vessel with contrast showing a visualized anatomical landmark. Intravascular imaging data is obtained during the translation procedure that includes one or more intravascular images showing a detected anatomical landmark. The starting location and the ending location of the imaging element on the extravascular imaging data is marked, and the predicted location of the detected anatomical landmark on the extravascular imaging data is marked. The predicted location of the detected anatomical landmark is then aligned with the visualized anatomical landmark.