A photoacoustic image generation apparatus includes: a puncture needle that generates photoacoustic waves; an ultrasound probe that detects the photoacoustic waves and reflected ultrasonic waves reflected by the transmission of ultrasonic waves; a processor that generates a color Doppler signal of a region of interest as a color Doppler measurement target, generates a photoacoustic image on the basis of the photoacoustic waves, and detects the position of a tip portion of the puncture needle on the basis of the photoacoustic image; and a controller that sets the region of interest such that the position of the tip portion of the puncture needle and a center position of the region of interest are separated from each other by a predetermined distance and sets the region of interest, following the movement of the tip portion of the puncture needle, in a state in which the distance is maintained.

Prostate biopsy systems are provided that include a 3D ultrasound probe support configured to receive an ultrasound probe for transperineal imaging. One or more template grids can have a plurality of apertures extending therethrough to receive and guide a biopsy needle along a trajectory associated with respective apertures when the template grid is fixed to the support and the biopsy system is positioned in the perineal area of a patient. Patient-specific template grids can also be developed and produced. This system enables fully transperineal prostate biopsy (i.e. both imaging and needle placement are perineal) and eliminates the need for an external racking device for image fusion as well as needle tracking. In addition, it reduces the infection risk associated to transrectal approach.

A minimally invasive system comprises an elongate medical instrument including a flexible body. The flexible body includes a wall including a channel, and the channel includes a groove. The flexible body further includes a lumen defined by an interior surface of the wall and a curved distal tip portion. The elongate medical instrument further includes a shape sensor coupled to the flexible body. The shape sensor is at least partially positioned within the groove, and the shape sensor is configured to detect shape characteristics of at least a portion of the flexible body. The system further includes an actuator for manipulating the elongate medical instrument.

A transperineal biopsy guide including a guide member and a displacement member supported by the guide member. The guide member may be configured to operably couple with the transrectal probe and may include a distal end, a proximal end opposite the distal end, and a length extending along a longitudinal axis between the distal and proximal ends. The displacement member may be configured to support the access needle and displace the access needle along at least a portion of the length of the guide member between the distal and proximal ends. The access needle may extend into the subcutaneous tissue when the access needle is displaced to the distal end.

A biopsy and therapy device comprising: a needling unit for holding and inserting a biopsy needle; an imaging module comprising an ultrasound probe and an actuator for moving the probe in a reciprocal action; a first arcuate slide; a second arcuate slide in sliding engagement with the first arcuate slide and a linkage to which the first arcuate slide is mounted; said linkage arranged to move the first and second arcuate slides within a vertical plane; said needling unit mounted to said arcuate slide wherein the first and second arcuate slides are mounted perpendicular to each other so as to rotate the needling unit about respective first and second principal axes.

A device for detaching cells or tissue from a cavity in a subject, the device includes: an elongated member arranged to be moved within a lumen of a needle or a catheter; and at least one flexible member arranged at a distal end of the elongated member, wherein the flexible member is configured to be brought between a first, constrained configuration within the lumen of the needle or catheter, and a second, expanded configuration outside said lumen, wherein the flexible member in the second, expanded configuration is configured to conform to an inner geometry of a cavity in which the device is inserted.

Systems, methods, and devices are provided for assisting or performing guided interventional procedures using custom templates. The system uses pre-procedure scans of a patient's anatomy to identify targets and critical structures. A template is then manufactured containing guide elements. During a procedure, the template may be aligned to the patient and instruments passed though the guide elements and into various targets. The template may be aligned using one or more of, for example, a position sensing system or a live imaging modality to register the patient to the template. The system makes optional use of devices designed to immobilize or track an organ during therapy.

Endoscope apparatuses for generating at least one image of a portion of an object are described herein. The endoscope apparatus includes an ultrafine needle adapted for insertion into the object; a fiber probe that is slidably disposed in the ultrafine needle, the fiber probe including a plurality of optical fibers or cores that act as illumination optical fibers and collection optical fibers; an optical assembly that is coupled to the fiber probe, the optical assembly including: at least one transmission optical pathway to provide at least one excitation light signal to the portion of the object to be imaged during use; and at least one return optical pathway that is adapted to transmit reflected light signals from the portion of the object when it is illuminated during use with at least one sensor for generating at least one image via at least one set of optical elements.

A method for displaying guidance information using a graphical user interface during an medical procedure comprises displaying, in a first mode of the graphical user interface, first image data from a perspective corresponding to a distal end of an elongate device. The first image data includes a virtual roadmap. The method also comprises transitioning from the first mode of the graphical user interface to a second mode of the graphical user interface. The transition is based on an occurrence of a triggering condition. The method also comprises displaying, in the second mode of the graphical user interface, second image data from a perspective corresponding to the distal end of the elongate device. The second image data includes a target indicator corresponding to a target location and an alignment indicator corresponding to an expected location of the medical procedure at the target location.

Medical instrument for taking a tissue sample in the body, the instrument includes an inner tube and an outer tube mounted axially slideable over the inner tube. The inner tube possesses a distal end with a cutting spiral and a proximal end to turn the spiral in the tissue to be sampled. The outer tube possesses a distal end with a cutting edge to cut loose the tissue in the spiral by sliding the outer tube over the spiral. Both tubes over at least an overlapping axial length of 30 cm are executed flexibly bendable because over said length the tubes are provided with one or more grooves which extend through the wall of the tubes and which open upon torsion in one direction.