A method of operating an aspiration catheter having a proximal end and a distal end includes the acts of at least partially blocking the distal end of the aspiration catheter with an embolus, creating a vacuum at the distal end of the aspiration catheter with a vacuum source adjacent the proximal end of the aspiration catheter, at least partially relieving the vacuum at the distal end of the catheter by at least one of interrupting the vacuum from the vacuum source and venting the aspiration catheter with a vent fluid adjacent the proximal end, and repeating the acts of interrupting the vacuum and venting the aspiration catheter in a timing cycle that maximizes the time that the aspiration catheter is at vacuum and changes pressure at the distal end of the catheter from vacuum to at least atmospheric pressure during each cycle.

A system includes a pulse waveform generator and an ablation device coupled to the pulse waveform generator. The ablation device includes at least one electrode configured for ablation pulse delivery to tissue during use. The pulse waveform generator is configured to deliver voltage pulses to the ablation device in the form of a pulsed waveform. The pulsed waveform can include multiple levels of hierarchy, and multiple sets of electrodes can be activated such that their pulsed delivery is interleaved with one another.

An apparatus includes a body assembly, an acoustic waveguide, an ultrasonic blade, a liquid dispensing feature, and a control module. The liquid dispensing feature is positioned distally relative to the body assembly. The liquid dispensing feature is positioned adjacent to the ultrasonic blade. The liquid dispensing feature is configured to deliver a flow of cooling liquid to the ultrasonic blade. The control module is operable to regulate fluid flow through the liquid dispensing feature.

An interactive control unit is disclosed. The interactive control unit includes an interactive touchscreen display, an interface configured to couple the control unit to a surgical hub, a processor, and a memory coupled to the processor. The memory stores instructions executable by the processor to receive input commands from the interactive touchscreen display located inside a sterile field and transmit the input commands to the surgical hub to control devices coupled to the surgical hub located outside the sterile field.

A surgical instrument comprising a housing, a shaft, a loading unit, a firing member configured to perform a firing stroke, a motor, a battery, a firing trigger, a control system, an electronic lockout, and a firing trigger lockout is disclosed. The electronic lockout is configured to prevent the firing member from performing the firing stroke when the loadinq unit is not attached to the shaft. The electronic lockout is further configured to prevent the firing member from performing the firing stroke when the loading unit is attached to the shaft and the loading unit has been at least partially fired. The firing trigger lockout is in a locked position when the loading unit is not attached to the elongate shaft. The firing trigger lockout is in the locked position when the loading unit is attached to the elongate shaft and the loading unit has been at least partially fired.

A system and method for supplying microwave energy to tissue for microwave therapy includes an electrosurgical generator having an output for coupling to a surgical instrument. The electrosurgical generator includes a microwave energy source and a controller for controlling the operation of the electrosurgical generator. The surgical instrument, coupled to the electrosurgical generator, includes a microwave antenna for delivering microwave energy from the microwave energy source. The controller of the electrosurgical generator is operable for causing the electrosurgical generator to apply at least two pulses of microwave energy.

Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.

Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the thrombectomy system. The system can include a catheter having a distal portion configured to be positioned adjacent to a thrombus in a blood vessel, an electrode disposed at the distal portion of the catheter, and an interventional element configured to be delivered through a lumen of the catheter. The electrode and the interventional element are each configured to be electrically coupled to an extracorporeal power supply.

Apparatus and associated methods relate to controlling electrical power of an electrotherapeutic signal that is provided to a biological tissue engaged by an electrosurgical instrument during a medical procedure. Electrical power—a product of a voltage difference across and an electrical current conducted by the engaged biological tissue—is controlled according to a therapeutic schedule. The electrotherapeutic schedule can be reduced or terminated in response to a termination criterion being met. In some examples, the termination criterion is a current characteristic, such as, for example, a decrease in current conducted by the engaged biological tissue. In some examples, the termination criterion is a biological tissue resistance characteristic, such as, for example, an increase in the biological tissue resistance that exceeds a predetermined delta resistance value.

Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.