A tissue removal system is provided which enables optimally performing a full-thickness resection of a hollow organ while minimizing invasiveness. In this tissue removal system, a tissue pressing tool which has a tissue contacting part and which is guided into the abdominal cavity, and a resection and anastomosis device work together. The resection and anastomosis device resects and performs anastomosis of tissue positioned between a main body and an anvil part, and, when pressing the tissue to be cut to the cutting position of the resection and anastomosis device by means of the tissue contacting part, the tissue contacting part is pressed against two abutment parts of the resection and anastomosis device.

Systems and methods of delivering a patch to a target site of a patient are described herein. The patch may comprise a biomaterial such as chitosan or extracellular matrix and may be biocompatible and/or bioresorbable. The system may include an endoscope, a patch, and one of an instrument or a cap, the patch being coupled to the respective instrument or cap and detachable therefrom. Methods of delivering the patch to the target site may include introducing an endoscope into a gastrointestinal tract of a patient, e.g., the patch being in a folded or crimped configuration, navigating a distal end of the endoscope proximate a target site; and applying the patch to the target site while releasing the patch from the endoscope.

A tissue cutting device has an outer sleeve with a distal window and an inner cutting sleeve which moves past the window to cut tissue. The inner cutting sleeve has a lumen which may have a larger proximal diameter than distal diameter. A perimeter of the window may comprise a dielectric material. A distal edge of the inner sleeve may be displaced inwardly.

A tissue pressing tool includes: a shaft that extends in one direction; a tissue pressing part that is a rod-like or belt-like member having a rigidity enough to hold a shape thereof even when pressed against a tissue; and a passive bending part that is arranged between the tissue pressing part and the shaft so that the tissue pressing part is capable of bending in all direction around an axis line of the shaft so as to keep an inverted state of the tissue by the tissue pressing part pressing the tissue linearly

To provide a treatment instrument that combines a capability to grip a target tissue and a capability to resect and ablate the target tissue without the need to interchange left and right devices or adjust a field of view of an endoscope, which can reduce burden on a surgeon.

A high frequency forceps includes a pair of forceps pieces configured to open and close on a pivot and equipped with incision blades adapted to pass a high-frequency current to a living tissue, in which the incision blades are formed, respectively, on opposite faces of the pair of forceps pieces, extending from a side of the pivot to a distal side; and the incision blades are spaced away from each other when the pair of forceps pieces is closed.

A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

A surgical system for performing an endoscopic submucosal dissection includes first and second surgical clips each having first and second jaw members for grasping tissue therebetween. The first surgical clip includes a resilient member attached to one of the jaw members and configured to bow outwardly to engage tissue. The jaw members of the first surgical clip each has a pointed tip and each of the jaw members of the second surgical clip has a blunt distal tip.

Systems, devices and methods for performing medical procedures in the intestine of a patient are provided. A medical device for performing a treatment and/or a diagnostic procedure can include an elongate shaft assembly comprising at least a shaft assembly first section comprising a distal section of the shaft assembly, and a shaft assembly second section proximal to the first section, and a functional assembly positioned on the shaft assembly first section. Additional sections of the shaft assembly can be included, and each section can comprise a different construction, such as to achieve a different stiffness as described herein. Variable stiffness along the length of the shaft assembly can be provided to aid in translation of the device through the patient's GI tract (e.g. through the stomach and into the small intestine), as described herein.

A system for performing minimally invasive procedures in a body lumen of a patient including a flexible catheter having a first lumen configured and dimensioned to receive an endoscope therethrough and a second lumen configured and dimensioned to receive a first flexible tube therethrough. The first flexible tube is movable through the second lumen and has a distal portion including a first curve extending in a first direction with respect to the longitudinal axis and a second curve extending in a second different direction with respect to the longitudinal axis. A retractor system is positioned at a distal portion of the catheter and is movable from a non-expanded insertion position to an expanded position forming an expanded cage to form a larger working space. The distal portion of the first flexible tube is movable within the expanded cage.

Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an elongate body having a cavity at a distal end and a tissue retractor extendable distally from the distal end of the elongate body. The tissue retractor may include an expansion mechanism. The expansion mechanism may include a plurality of arms each having a first end coupled around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a second end of the arms is engageable with selected tissue for resection of the body lumen. The tissue resection device may further include a tissue resecting device.