There are provided systems and methods for production of security screens. Each security screen may include an infill sheet and panel assemblies engaging the infill sheet to form a panel. At least one panel assembly may include an outer sash comprising two sidewalls defining a channel therebetween, and an inner member received in the channel of the outer sash with the inner member, in turn, receiving the infill sheet. A production system may include: a cutting station using computer numerical control cutting to cut materials to form the outer sash and the inner member; a routing station receiving the cut outer sash and a profile identifying a routing style of the outer sash, the routing station using a CNC machine to form recesses in the outer sash according to the routing style; and a panel assembly station assembling the infill sheet, outer sash, and inner member to form the panel.