The present invention is directed to a device for delivering a sealant to a tissue, comprising a sealant compartment, a cooling gas compartment, and a heater, all disposed inside a unified housing; with heater configured for rendering the sealant liquid or semi-liquid or molten and flowable; with sealant compartment configured for expressing the sealant in a flowable form from device via an exit nozzle; with gas compartment configured for expressing a cooling gas via a gas expression port; with exit nozzle and gas expression port co-directed into the same direction.

An apparatus and method for introducing portals into bone is described herein. An example apparatus for introducing portals into bone includes a handle, a base, and a driving member. The driving member can be made to project past the base by operating the handle. The base is detachable from the handle. The apparatus also includes a guide coupled at a first end to the handle and at a second end to the base. The base is detachably coupled to the guide. A base coupling detachably coupling the base to the guide includes an actuating member movable between a coupled configuration wherein the base is coupled to the guide and an uncoupled configuration wherein the base is released from the guide. The actuating member is arranged so that motion of the handle toward the base moves the actuating member from the coupled configuration to the uncoupled configuration.

Canisters are provided that include a cylindrical body and a cap welded to the body to define a cavity filled with carbon dioxide or other fluid. The canisters may be loaded into a medical device, e.g., to provide an energy source for operating the device. Methods for making such canisters are also provided.

Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.

Canisters are provided that include a cylindrical body and a cap welded to the body to define a cavity filled with carbon dioxide or other fluid. The canisters may be loaded into a medical device, e.g., to provide an energy source for operating the device. Methods for making such canisters are also provided.

A dynamic balloon angioplasty system for applying a dynamic pressure to fracture hardened materials embedded within an elastic conduit. The system having a pressure source system outputting at least a first predetermined pressure from a pressure source outlet, and an angioplasty unit fluidly coupled to the pressure source outlet receiving at least the first predetermined pressure. The angioplasty unit having an angioplasty inflation device, an angioplasty balloon connector, and an oscillating mechanism selectively actuated to output a plurality of pressure pulses to the angioplasty balloon via a fluid communication path. A control system is configured to determine an optimal hydraulic pressure oscillation frequency and amplitude for a given procedure and output a control signal to the oscillating mechanism, and monitor a pressure signal to detect fracture of the hardened material within the elastic conduit or system failure or leakage.

A medical shaft-type instrument includes an instrument head for applying clamps, the instrument head connectable via an instrument shaft to an instrument handle for actuating the instrument head. The instrument also includes a clip magazine having a housing, in which magazine a plurality of clamps are bunkered at a predetermined storage position spacing to each other according to the storage principle. All of the clamps can be moved forward by one storage position by a reciprocating transport and entraining rail within the scope of a single delivery stroke. The transport and entraining rail has one clamp entraining element per clamp. The relative distance of the individual clamp entraining elements differs from the respective storage position distances of the clamps in such a way that the entrainment of the bunkered clamps is carried out within the scope of one single delivery stroke in a clocked way.

A medical device may include a shaft extending between a proximal end and a distal end. The shaft may include a lumen therein. The medical device may include a handle coupled to the proximal end of the shaft and may include a mode selector. The mode selector may be adapted to transition between a first mode and a second mode of the medical device. The medical device may further include a compressed fluid source. In the first mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a negative pressure in at least a portion of the lumen. In the second mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a positive pressure in the at least a portion of the lumen.

A medical shaft instrument includes an instrument head with at least one jaw member for applying clamps with two jaw member branches. The instrument head is connectable over an instrument shaft having an outer tube with a handle for actuation of the jaw member. A clip magazine includes a retaining rail for supporting clamps in a predetermined storage position distance from each other. All the clamps are advanceable by a forth and back movable conveying and advancing rail. The clamp closest to the instrument head is conveyable by a tongue into the jaw member between the jaw member branches. The retaining rail has a distally extending support plate or bridge, which covers a jaw member region of a jaw member branch on the other jaw member branch facing side such that a tipping of an advanced or advanceable clamp on the jaw member branch is prevented.

An intraosseous access system, including an access assembly having a needle configured to drill into bone via rotation of the needle and a driver. The driver can include a housing, a power converter configured to impart rotational power to the needle, a first power source coupled to the power converter, and a second power source selectively coupleable to the power converter, where the second power source is configured to be disposed at least partially external to the housing. A method of drilling through a bone includes providing the intraosseous access system, applying rotational power to the needle, and placing the needle in contact with the bone. The method can further include coupling the second power source to the power converter so that power from the second power source is combined with power from the first energy source.