Apparatuses and methods for use in surgical vascular anastomotic procedures. Apparatus includes a blood vessel inner wall (BVIW) sealing and hole forming device, and a hole forming actuator. BVIW sealing and hole forming device includes a hole sealing device, and an anastomotic hole generating device. Hole sealing device includes a sheath that fully encloses and holds a self-expanding hole sealing assembly, a manual hole sealing controller assembly, and a flexible control wire enclosed within a flexible tube. Anastomotic hole generating device includes outer and inner assemblies, with a conically shaped anastomotic hole generating member. Hole forming actuator includes outer and inner assemblies. Also disclosed are procedures for performing surgical vascular anastomosis using the disclosed apparatuses and methods. Particularly applicable for use in clampless types of (end-to-side) surgical vascular anastomotic procedures, for performing coronary artery bypass grafting (CABG).

The present disclosure provides a device and methods for acquiring tissue within a lumen or for closure of bodily openings.

The present application discloses devices and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part, temporarily sealing a vascular access site, flushing the tissue tract with a flushing fluid via the sheath, dispensing a procoagulant material into the tissue tract adjacent the vascular access site via the sheath, and then unsealing the vascular access site to cause coagulation of blood adjacent the vascular access site.

Apparatuses and methods for use in surgical vascular anastomotic procedures. Apparatus includes a blood vessel inner wall (BVIW) sealing and hole forming device, and a hole forming actuator. BVIW sealing and hole forming device includes a hole sealing device, and an anastomotic hole generating device. Hole sealing device includes a sheath that fully encloses and holds a self-expanding hole sealing assembly, a manual hole sealing controller assembly, and a flexible control wire enclosed within a flexible tube. Anastomotic hole generating device includes outer and inner assemblies, with a conically shaped anastomotic hole generating member. Hole forming actuator includes outer and inner assemblies. Also disclosed are procedures for performing surgical vascular anastomosis using the disclosed apparatuses and methods. Particularly applicable for use in clampless types of (end-to-side) surgical vascular anastomotic procedures, for performing coronary artery bypass grafting (CABG).

An adhesion promotion device is disclosed, which is capable of reducing risk factors of an anastomotic leakage after surgery. The adhesion promotion device includes a sheet-shaped first region disposed between one joint target site and the other joint target site of biological organs to promote adhesion of a biological tissue, a second region provided inward of the first region and separated from the first region in a direction intersecting with a surface direction of the first region, and an interlock portion that interlocks the first region and the second region with each other.

A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device.

A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.

The provided technologies provide an implant closure device having a mesh layer formed on a flexible substrate, collectively forming a sealable member, that improves a seal formed over an aperture in a body lumen. The mesh facilitates a faster and more secure adherence of the sealable member to the surrounding edges at the puncture site. Furthermore, the provided technology may promote platelet-capture and encourage localized platelet aggregation at the exposed collagen in the wound edges on the mesh layer. The platelet impregnated mesh layer can facilitate cellular adhesion, enabling the sealable member that is local to the wound opening to act, in essence, as a “biological glue.”

The present application discloses devices and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part, temporarily sealing a vascular access site, flushing the tissue tract with a flushing fluid via the sheath, dispensing a procoagulant material into the tissue tract adjacent the vascular access site via the sheath, and then unsealing the vascular access site to cause coagulation of blood adjacent the vascular access site.

A percutaneous device for achieving hemostasis in a vessel, particularly a device for achieving hemostasis following the failure of a vascular closure device has a catheter with an attached inflation device. The catheter preferably has two different lumens, one for a guide wire and one for fluid used to inflate the inflation device. When inflated, the inflation device unfurls to block the puncture in the blood vessel. Distal blood flow continues uninterrupted with the device in the furled and unfurled state, preventing any issues distally from the puncture site.