The present disclosure describes medical devices comprising a bio-corrodible stent member and a graft member. The bio-corrodible stent member can comprise a metal applied directly to the graft member via a vapor deposition process, such as a chemical or physical vapor deposition process.

An anastomosis clamp (1) and a delivery system thereof, where the anastomosis clamp (1) includes inner lancets (102, 602), round corners (103, 603), and outer rings (101, 601) that are sequentially connected; the delivery system may be used in cooperation with the anastomosis clamp (1); and the delivery system includes a distal end (2), a middle flexible sheath (3), and a handle (4).

A system is provided for causing hemostasis at a puncture and a puncture tract. The system includes an inner member comprising an expandable member at its distal end and an inflation lumen that extends from inner member proximal end to an interior of the expandable member. The system further includes an outer member comprising a lumen sized and shaped to allow the inner member to slide therein, an occlusion balloon at its distal end, and an inflation lumen that extends from its proximal end to the interior of the occlusion balloon. The expandable member can be inflated by fluid flowing through the inner member inflation lumen so that the expandable member can close a puncture in a subcutaneous vessel of a living being. The occlusion balloon can be inflated by fluid flowing through the outer member inflation lumen so that the occlusion balloon can contact and apply pressure to a puncture tract extending from the skin of the living being to the puncture.

The present disclosure relates to a gastrointestinal delivery device of a dressing, where the delivery device is capable of fitting through a narrow channel before expanding and applying the dressing. The gastrointestinal delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein.

A gastrocutaneous closure device allows gastrocutaneous fistula closure from external abdominal access through the fistula site. Access through the fistula ensures accurate closure placement on the interior lumen wall of the stomach. A closure or clip has a plurality of prongs defined by a deformable material, such that the prongs extend radially from a central hub in an arcuate or curved, semicircular shape. The arcuate shape converges towards a central point or axis at a distal end, and the proximate end of the prongs attaches to the central hub such that the prongs radiate from the hub and the distal end curves back toward the axis through the hub. The deformable prongs may therefore radially compress or retract to define a larger or smaller diameter. The fistula lies on the axis such that the biased, inserted prongs pull the inner stomach wall closed around the healing fistula.

A method of treating a heart includes radially expanding a housing component within a native atrioventricular valve. The housing component includes an atrial anchoring mechanism for deployment in the left atrium and ventricular prongs for engagement with native tissue in the left ventricle. The housing component also includes an interior passageway sized for receiving a valve component. After the housing component has been deployed, the valve component is radially expanded within the passageway of the housing component. The valve component includes three leaflets configured for allowing blood to flow from the left atrium to the left ventricle. After expansion within the housing component, the valve component may have an inflow end portion that protrudes above the housing component into the left atrium. The housing component and valve component are preferably collapsible for advancement through a patient's vasculature using one or more catheters.

An extravascular access system includes a tubular stent configured to be deployed in a blood vessel, the stent having a sidewall and a proximal end opening and an internal scaffolding comprising one or more structural members, and an elongate access catheter having a distal end portion configured to access the blood vessel wherein when the stent is deployed in the blood vessel, and the distal end portion of the catheter is inserted into the proximal end opening of the stent, the one or more internal structural members of the stent deflect the distal end portion of the catheter towards a wall of the blood vessel.

Devices, systems and methods are provided for enhancing mechanical strength of tissue, allowing direct and secure access to cardiac and vascular structures, either through tiny incisions or percutaneously. The method for accessing a cardiac chamber or a vascular conduit may include providing an access channel into tissue of the chamber or the conduit. The method may also include providing an energy-transducing element configured to provide heat within the access channel. The method may further include applying energy to the tissue or a tissue-stabilizing composition injected into, around, or adjacent to the tissue to mechanically enhance the access channel.

Some embodiments are directed to methods and systems for percutaneously treating dissections in a patient's vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. The anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point.

A method of treating a heart includes radially expanding a housing component within a native atrioventricular valve. The housing component includes an atrial anchoring mechanism for deployment in the left atrium and ventricular prongs for engagement with native tissue in the left ventricle. The housing component also includes an interior passageway sized for receiving a valve component. After the housing component has been deployed, the valve component is radially expanded within the passageway of the housing component. The valve component includes three leaflets configured for allowing blood to flow from the left atrium to the left ventricle. After expansion within the housing component, the valve component may have an inflow end portion that protrudes above the housing component into the left atrium. The housing component and valve component are preferably collapsible for advancement through a patient's vasculature using one or more catheters.