A surface-modified cannula includes a hollow shaft having a proximal opening and one or more surface features along a portion of the length of the hollow shaft, the one or more surface features including one or more channels, one or more depressions, and/or two or more ports each extending at least partially between an outer diameter and an inner diameter of the hollow shaft. The one or more surface features are configured to enable, upon delivery of the cannula to a position proximate to a wound site in the blood vessel, collection of the patient’s blood from the wound site, and ejection of the blood along an access path to the wound site, thereby enabling blood to migrate from the wound site to a region surrounding and extending from the wound site along the access path.

A first responder device for treating blood flow from a deep wound or a bodily cavity having an inflatable balloon, a first chamber accommodating a liquid arranged for inflating the balloon, a second chamber accommodating a cooling agent capable of dissolving in the liquid when coming in contact therewith, thereby lowering the temperature, a rupturable seal between the first and second chambers, and a structure for forcing the liquid out of the first chamber into the inflatable balloon, and for rupturing the rupturable seal.

A closure system for delivering a sealant to an arteriotomy. A distal section of the closure system can include overlapping inner and outer sleeves that can expand with expansion of the sealant. A proximal section of the closure system can include a handle portion and a sheath adapter extending from the handle portion. The handle portion can comprise one or more actuators that when depressed or engaged can assist in deployment of the sealant in the arteriotomy and can further include tamping of the sealant and/or retraction of an expandable member. The sheath adapter can removably engage a side port or an irrigation line of a standard procedural sheath. When the sheath adapter is secured to the procedural sheath, movement of the closure system can also move the procedural sheath.

Devices, systems and methods for cardiac and vascular access configured to allow for intracardiac access to conduct medical procedures. The devices, systems and methods are particularly useful in trans-cardiac extra-corporeal membrane oxygenation (ECMO) procedures, ventricular assist procedures, cardiopulmonary bypass, or other medical procedures where intracardiac access may be required.

A closure device (200) includes a filament (204), an anchor (208), a sealing pad (210), and an automatic driving mechanism. The anchor is configured to be inserted through the tissue wall puncture and is attached to the filament at the second end of the closure device. The sealing pad is slidingly attached to the filament at the second end of the closure device. The automatic driving mechanism includes a compaction member (212), at least one slide member (230, 232) at the first end of the closure device, and a biasing member (234). The biasing member is carried by the at least one slide member and operable to distally advance the compaction member for automatically compacting the sealing pad toward the anchor upon withdrawal of the closure device from the internal tissue wall puncture.

A device for folding an implant having a wing into a an overlapped configuration includes a funnel body comprising: a first portion configured to receive and protect the implant when the wing of the implant is in a flat or relaxed state, a second portion proximal to the first portion and configured to engage and fold opposite first and second side portions of the wing of the implant in a predetermined direction when the implant is retracted proximally from the first portion of the funnel body and into the second portion of the funnel body, and an overlap guide configured to direct the path of a first one of the side portions of the wing such that the first and second side portions of the wing are overlapped in a predetermined manner and to prevent respective edges of the first and second side portions of the wing from butting into each other as the first and second side portions of the wing are guided into the overlapping configuration during proximal retraction of the implant relative to the funnel body.

Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and/or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.

A bleeding control device for mitigating bleeding includes a housing, inflation means, an inflatable balloon and a gas supply line. The bleeding control device may be used to deliver variable contents to a wound at the site of injury to control the bleeding of a victim as temporary solution for mitigating the bleeding until more advanced medical care can be provided. A bleeding control device includes a canister housing, a compressed gas canister arranged within the canister housing, a tube connected to the canister housing, an inflatable balloon disposed on the tube, the inflatable balloon being fluidly connected to the compressed gas canister, and a control element configured to activate the compressed gas canister to inflate the inflatable balloon.

A deployment instrument for deploying a closure device for sealing a percutaneous puncture in a wall of a body passageway, the deployment instrument including a carrier assembly, wherein the carrier assembly is configured to hold the closure device in a pre-deployment state, and a tensioner assembly, wherein the filament is fixedly attached to the tensioner assembly, wherein the deployment instrument is configured to increase the tension in the filament upon linear movement of the deployment instrument away from the wall of the body passageway when the closure device is anchored to the wall via the anchor such that the tension is gradually increased as the deployment instrument is moved between a first linear distance and a second linear distance greater than the first linear distance from the wall of the body passageway.

A hemostatic device includes a first tube defining a first lumen configured to channel a fluid therethrough, and a second tube housing at least a portion of the first tube and at least partially defining a second lumen configured to retain a hemocoagulant agent therein. The second tube is moveable with respect to the first tube, such that the hemocoagulant agent is at least substantially retained within the second lumen when the second tube is in a first position, and the hemocoagulant agent is at least partially exposed when the second tube is in a second position.