Disclosed is a dermatological diagnostic and treatment system including a light source device, a light flow collecting device, a spectroscopic measurement device, and a computer. The light source device includes a laser source tunable in wavelength inside the spectral range, the laser source being tunable in duration and/or rate and the laser source being adapted to generate a second treatment laser beam of high intensity at said first wavelength towards the epidermal surface. The dermatological diagnostic and treatment system further includes a temperature sensor and a feedback device, the temperature sensor being arranged to record a temperature measurement signal of the epidermal surface as a function of the application of the second laser beam. The feedback device is configured to modify the duration and/or rate of the laser pulses as a function of the temperature measurement signal.

Embodiments of an actuating device for actuating a needle cartridge and puncturing an epidermis with controlled depth. The actuating device includes a motor housed in a motor housing, an actuating rod driven by the motor and configured to actuate in a reciprocating motion, and an adjustment mechanism. The actuating rod is housed in a rod housing, the rod housing forming a device aperture configured to receive a needle cartridge and to attach to the needle cartridge. The adjustment mechanism interfaces with the rod housing and is configured to adjust a position of the rod housing relative to the motor housing while not rotating the rod housing relative to the motor housing.

A device comprising a scalpet assembly including a first investing plate and a scalpet array. The scalpet array includes scalpets rotatably coupled to the first investing plate. Each scalpet includes a first thread on a portion of an outside surface, and a distal end configured as a cylindrical scalpel. The device includes a second investing plate comprising apertures corresponding to the scalpet array. Each aperture includes a second thread configured to receive the first thread. The corresponding scalpet is configured to rotate relative to the second thread and move along an axis of the scalpet relative to the second investing plate.

Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

SELECTIVE PHOTOTHERMOLYSIS (SP) IS A PRECISE PULSED-LIGHT MICROSURGERY METHOD, DESCRIBED BY ANDERSON AND PARRISH IN A PAPER PUBLISHED BY SCIENCE IN 1983 FOR TREATING LIGHT-ABSORPTIVE LESIONS AND UNWANTED PIGMENTS IN HUMAN TISSUE WITH MINIMAL COLLATERAL DAMAGES. LIGHT SOURCE WITH TUNABLE WAVELENGTH FOR SP IS THE MOST DESIRABLE FEATUER. HOWEVER, SUCH A LIGHT SOURCE IS NOT YET AVAILABLE. IN ADDITION, LIGHT PULSE-WIDTH AND LIGHT PULSE ENERGY ARE CRITICAL FOR SP SURGICAL OUTCOME. THIS INVENSION DISCLOSES TECHNIQUES, APPARATUS AND METHODS FOR OPTIMIZING SP SURGICAL OUTCOME. THE SAME TECHNIQUES APPLY TO SP SURGICAL SYSTEMS USING OTHER RADIATION SOURCES. SOME TECHNIQUES APPLY TO GENERAL SURGICAL SYSTEMS THAT HEAT UP LESIONS IN TISSUE, INCLUDING HIGH-INTENSITY-FOCUSED-ULTRASOUND THERAPIES.

In combined methods for treating a patient using time-varying magnetic field, treatment methods combine various approaches for aesthetic treatment. A magnetic field generating device is placed proximate to a body region of the patient. The magnetic field generating device generates a time-varying magnetic field with a magnetic flux density in a range of 0.5 to 7 Tesla. The time-varying magnetic field is applied to the body region of the patient in order to cause a contraction of a muscle within the body region. A second therapy may be used by applying one or more of optical waves, radio frequency waves, mechanical waves, negative or positive pressure or heat to the body region of the patient.

Methods and formulations for removing a tattoo by using a cell disrupter in combination with a vasodilator, and optionally one or more of an osmotic modifying agent, a chelation agent, and an occlusive modifying agent. Embodiments optionally further include using one or more of an antibiotic, anesthetic, penetration enhancer, excipient, carrier and vehicle.

Methods and systems are disclosed for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to electrical energy. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Embodiments include a system comprising a carrier and a cannula assembly. The carrier includes a proximal end and a distal end, and the proximal end is configured to removeably couple to a remote console. The cannula assembly, which is configured to removeably couple to the distal end of the carrier, is configured for rotational fractional resection (RFR) and includes at least one cannula rotatably coupled to the carrier and enclosed in a depth guide configured to control an insertion depth of the at least one cannula. The depth guide includes a vacuum chamber configured to form vacuum to evacuate resected tissue generated by the RFR.