A surgical device for closing a vaginal cuff includes a handle having an elongated shaft and a plurality of needles disposed therein. Each needle includes a suture anchor at a distal end thereof having a suture engaged therewith. An anvil is disposed at a distal end of the elongated shaft. A cutting mechanism is operably associated with the handle and is configured to cut tissue upon actuation thereof. A firing mechanism is operably associated with the handle and is movable between an unactuated position wherein the plurality of needles and suture anchors remain retained within the elongated shaft, an actuated position wherein the plurality of needles and suture anchors deploy from the elongated shaft through the cervical tissue, and a reverted position wherein the plurality of needles retract leaving the plurality of suture anchors and sutures engaged with the cervical tissue for tying off the vaginal cuff.

Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

In one embodiment, a suture attachment catheter configured to repair a heart valve by inserting a suture in a valve leaflet of a beating heart of a patient includes a handle control, a flexible catheter body, and a suture attachment assembly at a distal end of the catheter body. The suture attachment assembly can include a rail between a distal clamping jaw hingedly attached to the rail, and a proximal clamping jaw. One of the proximal clamping jaw or distal clamping jaw can be selectively slideable with respect to the other on the rail using a jaw actuator of the control handle to adjust a distance between the proximal clamping jaw and the distal clamping jaw. A needle can be selectively slideable within the catheter body by using a needle actuator of the proximal handle control to penetrate a valve leaflet and insert a suture through the valve leaflet when the valve leaflet is captured between the proximal clamping jaw and the distal clamping jaw.

A medical device and methods for hemostasis in a living body are disclosed. The medical device including a base configured to arranged on an upper surface of the tissue in the living body; a plurality of levers, each of the plurality of levers having a needle arranged on a lower surface thereof and configured to puncture the tissue in the living body, and wherein the plurality of lever are configured to be received with a slot or track of the base; and at least one tie, the at least one tie configured to hold together the plurality levers and needles upon compressing the tissue in the living body upon moving the plurality of levers inward in the slot or track of the base.

A device includes a selection lever pivotably coupled to a housing, a shaft coupled to the housing, and a distal end assembly coupled to the shaft. When the selection lever is in a first position and an actuation lever is pivoted from a first position to a second position, a tip of the first needle extends from a first position across a first tissue bite area to a second position in which the tip is disposed within a first ferrule recess of a receiver portion of the distal end assembly. When the selection lever is in a second position and the actuation lever is pivoted from the first position to the second position, a tip of the second needle extends from a first position across a second tissue bite area to a second position in which the tip is disposed within a second ferrule recess of the receiver portion.

A suturing device for minimally invasive surgery is disclosed. The suturing device has a head defining one or more ferrule holders and a tissue bite area. The device also has a first needle comprising a flywheel portion and one or more curved arms extending from the flywheel portion, each of the one or more curved arms comprising a ferrule engaging tip, wherein the first needle is pivotably coupled to the head. The suturing device further has a first actuator coupled to the first needle and configured to rotate it from a retracted position, where the ferrule engaging tip of each of the one or more curved arms starts away from the one or more ferrule holders, through the tissue bite area, and to an engaged position where the ferrule engaging tip of each of the one or more curved arms is operationally aligned with the one or more ferrule holders.

An adjustable heart valve repair system includes a suture implanting apparatus and a suture locker. The suture implanting apparatus is operable to implant a suture into at least one leaflet of a heart valve. The suture locker is operable to fix the suture. The suture locker includes an adjusting device to adjust tensioning or loosening of the suture.

Disclosed is a suture delivery device for endoscopically passing a suture into biological tissue. The device can include two hypodermic needles that can be manipulated via controls on a handle of the device in order to pass a suture from one needle to the other. For example, the device can include a first needle coupled to at least one loop member that, when deployed from the first needle, provides a target through which a second needle of the device can deliver the suture. Once the second needle intersects the loop member, the user can advance a length of suture out through a distal end of the second needle. The loop member can then be retracted into the first needle, thereby grabbing and securing the suture in the process.

A suture needle system includes a first needle and at least one second needle. Each of the first and second needles preferably has a common needle body construct. The first needle includes an elongate suture having a length sufficient to extend at least the length of an instrument channel of an endoscope. The second needle includes an opening formed by a loop of suture at which the second needle can be advanced over the elongate suture. In use, the first needle is secured to a first tissue location using an endoscopic suturing system. A second needle is advanced at its opening over the elongate suture and secured to a second tissue location. Additional second needles may be advanced over the elongate suture to respective tissue locations. The elongate suture is pulled taut, drawing the second needles into proximity, and secured.

A tissue closure system for closing vaginal tissue includes a tissue closure device having an end effector supporting one or more sutures securable to vaginal tissue. The one or more sutures may be separated from the end effector and tied to the vaginal tissue. The tissue closure system may include a tissue approximation device configured to apply negative pressure to vaginal tissue for approximating portions of the vaginal tissue together.