An insertion instrument is configured to eject at least one anchor body into respective target locations, and subsequently apply a predetermined tensile force at least one actuation member of the at least one anchor member so as to actuate the at least one anchor body from a first configuration to a second expanded configuration. The insertion instrument can include a tension assembly that applies the predetermined tensile force to the at least one actuation member. The predetermined tensile force can be defined by a distance of travel, a predetermined failure force of a fuse, or a combination of distance of travel and a predetermined failure force of a fuse.

A knot delivery device for securing a suture comprises an elongated body having a proximal end and a distal end, a pre-configured knot disposed at the distal end of the elongated body, a suture snare having a snare configured to capture suture material, wherein the snare extends through the pre-configured knot and a suture locker secured to one end of material forming the pre-configured knot, wherein tension applied to the suture locker tightens the pre-configured knot.

A method of coupling a first portion of an anatomy to a second portion of the anatomy includes coupling first and second bones of the anatomy with a bone-tendon-bone implant. The bone-tendon-bone implant has a first bone end, a second bone end and a replacement tendon between the first and second bone ends. The first and second bone ends are positioned in corresponding first and second bores of the first and second bones. The first bone end is secured to the first bone with a first bone anchor. A second anchor coupled to the bone-tendon-bone implant is passed through and outside the second bore. The second anchor is coupled to an adjustable suture construct having two adjustable suture loops. Tensioning at least one of first and second ends of the adjustable suture construct tensions the replacement tendon and positions the first bone relative to the second bone.

A method of soft tissue repair comprises attaching at least one suture to a soft tissue to be affixed to a bone structure, positioning a tissue anchor on a driver, positioning a cinching suture alongside the driver, engaging a catch of the cinching suture with a stop of the driver, capturing the at least one suture attached to the soft tissue in a loop of the cinching suture positioned proximate a distal tip of the driver, drawing the at least one suture toward the distal tip of the driver by pulling at least a first portion of the cinching suture; preventing the cinching suture from passing by the driver by engaging the catch with the stop, and installing the tissue anchor into the bone structure to secure the at least one suture in the bone structure by interference-friction fixation between the tissue anchor and the bone structure.

A system for repairing a meniscus includes a suture that includes a first anchor, a second anchor, and a flexible portion connecting the first anchor and the second anchor. The flexible portion includes a self-locking slide knot between the first anchor and the second anchor. The system also includes a needle having a longitudinal extending bore and an open end. The bore is configured to receive the first anchor and the second anchor. The system further includes a body portion operatively connected to the needle at a distal end of the body portion. The body portion has a lumen. The system also includes a pusher configured to rotate and slide within the lumen of the body portion and the longitudinal extending bore of the needle. The pusher has first and second stop surfaces, each of which is constructed and arranged to engage a proximal end of the body portion.

An anchor device and system for coupling soft tissue to osseous tissue includes a stopper member that supports a loop of suture material. A fixing member includes features that allow it to be rigidly coupled to surrounding bone and thus hold the stopper member in a cavity within the bone. The loop of suture material, in turn, supports a second suture device, which is coupled to, and thus retains, the soft tissue. In certain embodiments, the fixing member includes a wadding structure having a generally elastic property.

Devices, systems and methods for passing a suture. In general, described herein are suturing devices, such as suture passers, as well as methods of suturing tissue. These suture passing devices may include dual deployment suture passers in which a first distal jaw member is moveable at an angle with respect to the longitudinal axis of the elongate body of the device and the second distal jaw member is retractable proximally to the distal end region of the elongate body and/or the first jaw member.

A suturing catheter for reducing mitral insufficiency by applying suturing points percutaneously is provided. The suturing catheter has a catheter body provided with a distal end and at least one internal lumen, at least one U-folded suture filament with two free ends, each provided with a suture needle, a pair of stylets, each provided with a catch needle, the suture and catch needles being provided with a connecting portion that allows a catch needle to mechanically engage with a suture needle, and a lever having a stapling arm, from which the suture needles protrude. The stapling arm, together with the catheter body, from which the catch needles protrude, defines a catch zone for a flap of a mitral valve. An opposite operating arm, together with the catheter body, defines an operating zone of the lever.

Methods of tissue repair with a knotless tissue repair construct system is disclosed. System may include multiple anchor constructs that are soft anchor constructs. The multiple anchor constructs may include at least one knotless construct and may be inserted separately and coupled to each other as part of the method. The method may form a knotless all-suture staple construct. The method may form a knotless all-suture construct in a chain configuration. The method may include coupling a graft or bio-inductive material to the repair site. The method may include augmenting a ligament repair.

Tissue repair systems which use knotless all-suture anchors and have the ability to lock multiple repair sutures within the anchor construct. The anchor construct includes a tension suture wrapped or looped upon itself to create an open eyelet, through which multiple repair sutures originating in soft tissue are passed. The location of the eyelet may be anywhere inside the all-suture anchor or adjacent to the exterior of the anchor body. Tensioning of the tension suture causes the eyelet to restrict movement of the repair sutures and secures them within or against the anchor body.