Methods and systems for closing an opening or defect in tissue, closing a lumen or tubular structure, cinching or remodeling a cavity or repairing a valve preferably utilizing a purse string or elastic device. The preferred devices and methods are directed toward catheter-based percutaneous, transvascular techniques used to facilitate placement of the devices within lumens, such as blood vessels, or on or within the heart to perform structural defect repair, such as valvular or ventricular remodeling. In some methods, the catheter is positioned within the right ventricle, wherein the myocardial wall or left ventricle may be accessed through the septal wall to position a device configured to permit reshaping of the ventricle. The device may include a line or a plurality of anchors interconnected by a line. In one arrangement, the line is a coiled member.

A meniscal repair needle, comprising a needle rod, wherein the front section of the needle rod is warped in the shape of an arc and gradually reduces in size to form a needle tip as it extends forward, wherein the needle rod is configured to be a hollow structure, wherein a notch is formed in a front section of the needle rod, and wherein the notch expands inwards from the surface of the needle rod forming a hook portion, wherein an inner cavity of the needle rod extends into the notch, and wherein a hook tip of the hook portion faces the rear of the needle rod, wherein a rear section of the needle rod is connected with a hand-held portion.

Provided are a one-way lifting embedded thread, a lifting device and a plastic surgery method using the same. The one-way lifting embedded thread includes a pulling thread and at least one cam body sleeved on the pulling thread. Two ends of the pulling thread are a lifting end and a free end. The free end is provided with an anchor structure for securing the pulling thread. Two sides of the cam body are a large end face and a small end face. The large end face of the cam body faces the free end of the pulling thread. As for the one-way lifting embedded thread, the arrangement of the anchor structure secures the one-way lifting embedded thread to the skin tissue temporarily and prevents the lifting embedded thread from completely slipping into the skin tissue.

Disclosed are apparatus and method for forming passage extending along a plane crossing an organ's volumetric region from an entry point to an opposing exit point at a surface of the organ, and for passing a tension member around the volumetric region by pulling the tension member from the exit point to the entry point through the passage. The apparatus can include a rigid outer tube with a tip for penetrating the organ and reach a penetration depth; an inner needle with elastic body configured to pass straightened through outer tube lumen and to partially protrude and voluntarily flex to a curved form greater than the diameter of the volumetric region; and a tension member passer with a pulling portion for engaging with portion of tension member and for pulling the tension member when withdrawn.

A fistula treatment system comprises a guide such as a guide coil 1101 which is adapted to extend partially around a tissue tract and an implant element 1102. The implant element 1102 is activated to draw tissue surrounding the tract inwardly.

Veins and other blood vessels may be reshaped by introducing an implant through the vessel walls with anchors positioned on opposite sides of the wall. The anchors typically include an elongate body having coils or other anchors formed therein. The implants may be delivered percutaneously using a cannula which can hold the anchor externally or internally. The methods and devices are useful in treating a dorsal vein to reduce blood flow in patients suffering from erectile dysfunction.

An insertion instrument is configured to eject at least one anchor body into respective target locations, and subsequently apply a predetermined tensile force at least one actuation member of the at least one anchor member so as to actuate the at least one anchor body from a first configuration to a second expanded configuration. The insertion instrument can include a tension assembly that applies the predetermined tensile force to the at least one actuation member. The predetermined tensile force can be defined by a distance of travel, a predetermined failure force of a fuse, or a combination of distance of travel and a predetermined failure force of a fuse.

A thread lift cannula has a plurality of therapeutic liquid discharge ports to enable the discharge of a therapeutic liquid into the surrounding tissue. The therapeutic liquid may be injected into the thread lift cannula conduit by a syringe and the thread therein may be bioresorbable and absorb the therapeutic liquid. The therapeutic liquid may include a medicament to reduce swelling or to treat pain, or a biologic that aids in collagen creation, formation, or restructuring. The plurality of therapeutic liquid discharge ports may vary in size along the length of the cannula. A distal discharge port may be larger than a proximal discharge port to enable a more uniform delivery of therapeutic liquid along the cannula. A therapeutic liquid discharge port may be configured at a port angle, offset from orthogonally through the wall of the cannula, to prevent blockage of the outlet opening of the discharge port.

A system for repairing a meniscus includes a suture that includes a first anchor, a second anchor, and a flexible portion connecting the first anchor and the second anchor. The flexible portion includes a self-locking slide knot between the first anchor and the second anchor. The system also includes a needle having a longitudinal extending bore and an open end. The bore is configured to receive the first anchor and the second anchor. The system further includes a body portion operatively connected to the needle at a distal end of the body portion. The body portion has a lumen. The system also includes a pusher configured to rotate and slide within the lumen of the body portion and the longitudinal extending bore of the needle. The pusher has first and second stop surfaces, each of which is constructed and arranged to engage a proximal end of the body portion.

A method and apparatus for positioning a locator. The method includes inserting a tissue locator through an opening in a tissue wall, and advancing an engagement member to move a portion of the first arm from a first position to a second position that is separated from a longitudinal axis of the tissue locator by a greater distance than the first position.