A locking suture construct having suture material with a first end and a second end, each attached to a first body in a slidable manner, a constricting member formed in the second end of the suture material, and a bight in the suture material between the first end and the second end. The bight can be pulled through the constricting member around a second body to create a locking loop. The first end and the second end are passed through the locking loop. Pulling the first end increases a perimeter of the locking loop and moves the constricting member toward the second body. When the constricting member reaches the second body, pulling the first end reduces the perimeter of the locking loop and moves/rotates the constricting member around the second body toward the first body to hold the first body in relative position to the second body.

A device for closing an aperture in a vessel wall including a covering member positionable inside the vessel against the internal opening of the aperture and having a dimension to prevent egress of fluid through the aperture. The covering member has a proximal surface and a distal surface, the distal surface having a concave surface and the proximal surface having a raised surface, wherein four openings are positioned in the raised surface. First and second retainers are positionable external of the vessel and first and second connecting members advance the respective first and second retainers toward the covering member.

A device for closing an aperture in a vessel wall including a covering member positionable inside the vessel against the internal opening of the aperture and having a dimension to prevent egress of fluid through the aperture. The covering member has a proximal surface and a distal surface, the distal surface having a concave surface and the proximal surface having a raised surface, wherein four openings are positioned in the raised surface. First and second retainers are positionable external of the vessel and first and second connecting members advance the respective first and second retainers toward the covering member.

A medical device for approximating and securing tissue without requiring knots includes a lock-head, a strap section, distal protuberance, and a leader section. The device also includes a transition section between the leader and the strap section and a stiffening section proximal to the protuberance. The leader section is used to draw the strap section into the body through small apertures in tissue and the transition section provides a gradual transition in stiffness and size between the leader and the strap section. Tensioner and cutter and a threading tool configured to be slidably removed from a lumen of the tensioner and cutter is provided. A blade within the lumen of the tensioner and cutter is provided to cut excess leader and/or strap when the procedure is completed.

Provided is a lifting cog thread (100) having a predetermined length. The lifting cog thread includes a molded hook portion provided on an outer circumferential surface of the thread. The molded hook portion includes molded recesses (110) and molded protrusions (120) alternating with the molded recesses. The molded hook portion has a spline shape produced by mold processing using a rotational mold processing apparatus. The thread (100) prevents non-uniform pulling in which skin catching force is relatively weakened in a portion of the thread (100).

Knotless suture-based implant systems and related methods for joining bone and/or tissue portions is disclosed. The implant systems include a flexible anchor tube comprising an annular side wall defining an internal cavity, a first longitudinal end and a second longitudinal end. The implant systems also comprise a suture that extends through the side wall of the anchor tube a plurality of times and forms a free loop portion that extends from the side wall. The implant systems further comprise at least one suture passer extending through a portion of the loop portion of the suture configured to translate first and second end portions of the suture through the loop portion via translation of the at least one suture passer. The suture extends along a pattern that allows the suture to slide through the anchor tube when the first and second end portions of the suture are tensioned.

According to the aspect of the present disclosure, various forms of medical 3D threads produced using ultrasonic waves are provided. Thus, we can expect high satisfaction with the medical 3D threads having high tensile strength and holding power. The medical 3D threads can be produced to have about twice as many barbs as conventional medical threads and can be produced using ultrasonic waves without damaging yarn or making knots. Thus, it is possible to overcome the cause of a decrease in physical strength.

The present disclosure describes a medical construct. The medical construct includes a first layer comprising an array of collagen fibers, the first layer forming a core of the medical construct, and a second layer comprising a plurality of braided collagen fibers, wherein the second layer surrounds the core of the medical construct. In some embodiments, the medical construct may further include a third layer comprising a plurality of braided collagen fibers, wherein the third layer surrounds the second layer. Methods of manufacturing a medical construct also provided.

A locking suture construct having suture material with a first end and a second end, each attached to a first body in a slidable manner, a constricting member formed in the second end of the suture material, and a bight in the suture material between the first end and the second end. The bight can be pulled through the constricting member around a second body to create a locking loop. The first end and the second end are passed through the locking loop. Pulling the first end increases a perimeter of the locking loop and moves the constricting member toward the second body. When the constricting member reaches the second body, pulling the first end reduces the perimeter of the locking loop and moves/rotates the constricting member around the second body toward the first body to hold the first body in relative position to the second body.