Disclosed are methods and devices for endocardial left atrial appendage management (LAAM) by inversion and excision. The methods may comprise inserting an inverter apparatus into an interior cavity of the left atrial appendage (LAA) of a subject and inverting the LAA, closing the base portion of the inverted LAA with the one or more closure devices, separating the inverted LAA from the left atrium with a separation apparatus positioned at the base portion of the inverted LAA adjacent to the one or more closure devices, and removing the separated LAA from the subject.

Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

An apparatus and method is provided for accessing an abdominal cavity of a patient via the anus for any number of surgical operations, e.g., colon cancer, appendectomy, lymph node biopsy, etc. The apparatus includes a tubular body that extends to an open end having a plurality of holes. The tubular body is inserted into the intestine of the patient, and a clamp is inserted through the tubular body of the apparatus and into the intestine. The clamp and the attached intestine is then pulled into the tubular body, so that the intestine can then be cut. The clamp and the adjacent intestine are then moved out of the tubular body so that the surgery may be performed through the intestine. The cut ends of the intestine can then be reattached (e.g., stapled, sutured, etc.) following completion of the surgery.

A medical device may include an implantable device for treating a body tissue structure. The implantable device may include a wire structure which may include a wave pattern. The wire structure may be elastic so as to provide a pressure around the body tissue structure such that the pressure may change with movement of the body tissue structure.

Systems, devices, and methods are provided for securing soft tissue to bone, for securing one or more objects using a surgical filament, and for drawing two or more tissues together so they can be secured in a desired location. One exemplary embodiment of a surgical repair construct that is configured to atraumatically pass through soft tissue to secure tissue in a knotless manner includes a snare linkage, a collapsible loop, and a flexible suture pin. The snare linkage can include a collapsible snare for receiving the collapsible loop, and in use the snare can be collapsed around the collapsible loop and advanced distally towards the bone until the snare is proximate to the tissue, while the collapsible loop can be collapsed distally towards the bone to bring the tissue into proximity with the bone. Other exemplary systems, devices, and methods for use with soft tissue repair are also provided.

The present disclosure relates to treatment of reflux disease of a human patient. More particularly, a device is disclosed, which is configured to be implanted in the body of the human to restrict movement of the cardia of the patient's stomach towards the diaphragm opening into the patient's thorax, and/or to prevent stomach contents from passing from the stomach into the esophagus.

In some aspects, the present disclosure provides a delivery device for delivering a detachable medical implant that comprises an elongated delivery member and a first engagement portion. The first engagement portion comprises a first proximal-facing surface, a first distal-facing surface, and a first lumen that is configured to accommodate an activation wire, wherein at least 50% of a surface area of the first proximal-facing surface is angled away from a proximal end of the first engagement portion. In other aspects, the present disclosure provides a medical delivery system comprising: such a delivery device; an implantable device comprising a medical device portion and a second engagement portion, the second engagement portion comprising a second lumen configured to accommodate an activation wire, a second proximal-facing surface and a second distal-facing surface; and an activation wire. Other aspects pertain to methods of medical device delivery using such a medical delivery system.

A suturing device (1) for suturing parts (5,6) together of a lumen (8) with one or more sutures (3) comprises an actuator (34) having a handle (33) and first and second operating elements (60,68) slideable longitudinally on the handle (33). A tubular shield (35) extends from the handle (33), and a cannula (40) slideable in the tubular shield (35) is connected to the first operating element (60) for urging the cannula (40) between a withdrawn state within the tubular shield (35) to an extended state extending from the tubular shield (35). An elongated push rod (52) slideable in the cannula (40) terminating in a distal hook (55) is coupled to and operated by the second operating element (68). Anchor elements (22) of the suture (3) are located in the cannula (40), and are sequentially urged therefrom by the push rod (52), as the cannula (40) sequentially pierces through the parts (5,6). A loop (26) of the suture (3) is engaged by the hook (55), which is then withdrawn into the tubular shield (35) for engaging the adjustment element (25) of the suture (3) against an abutment face (38) of the tubular shield (35) for in turn drawing the anchor elements (22), and in turn the parts (5,6) of the colon (8) together. The adjustment element retains the parts (5,6) together.

A surgical instrument is disclosed. The instrument includes a handle configured to move between an open position and a closed position; at least one clamping structure coupled to the handle. The at least one clamping structure includes a first set of pushing members operatively coupled to the handle. The movement of the handle from open position to the closed position facilitates the movement of pushing members into longitudinal direction. The at least one clamping structure includes a set of constrictors coupled to the set of the pushing members such that movement of the set of the pushing members enables movement of the set of constrictors from a designed position in which the set of constrictors are positioned away from each other and to a contracted position in which the set of constrictors are positioned closed to each other.

The present subject matter provides a system for temporarily stopping blood flow through a blood vessel, the system including: at least one magnetically attractive element configured to be introduced into an internal part of a body of a patient, and temporarily placed near a first blood vessel that supplies blood to at least one second blood vessel; and at least one magnetic field generator configured to be placed outside a body of the patient, and generate a magnetic field that attracts the at least one magnetically attractive element in a manner that the at least one magnetically attractive element presses the first blood vessel, thereby stopping flow of blood through the first blood vessel toward the second blood vessel. Additional embodiments of the system, of a kit comprising components of the same, and a method for temporarily stopping blood flow through a blood vessel, are disclosed herein as well.