An implantable sphincter assistance device is configured to surround an exterior wall of an esophagus. The implantable sphincter assistance device includes a plurality of beads, at least one connector, and secondary material. Each of the beads has an exterior surface. The connector is configured to serially connect the beads to form a ring. The secondary material is configured to be disposed between the exterior surface of at least one of the beads and the exterior wall of the esophagus. The secondary material is configured to control remodeling of tissue surrounding the exterior wall of the esophagus.

An example assembly for use with a vacuum system and an esophageal positioning device esophageal positioning device includes an introducer, in which the esophageal positioning device includes a first segment and a second segment. The second segment is pivotally connected to the first segment. A gap portion of an outer tube of the introducer is defined along a longitudinal axis between a tube tip of the introducer and the distal end of the second segment of the esophageal positioning device when the esophageal positioning device is disposed within the introducer. The gap portion defines one or more radial vacuum holes.

A probe may be inserted into a body cavity to perform diagnostic intervention(s), therapeutic intervention(s), or both. The probe may be inserted through a body aperture that is naturally occurring or man-made, intentionally or by accident. The body aperture may form a seal encircling the probe so that insufflation retention material may be effectively retained in the body cavity so that an operator can perform the intervention(s). However, there may be leakage of the insufflation material. The insufflation retention device is configured to form an effective seal contactingly adjacent the body aperture and to provide a passageway for the introduction of the probe into the body cavity, such that a diagnostic intervention or therapeutic intervention or both may be performed.

The present disclosure generally relates to devices, systems, and methods for Fallopian tube diagnostics. In some embodiments, a tube may have a distal end, and a balloon may be coupled to the distal end of the tube. The balloon may be disposed in the tube in a first, inverted position and movable to a second, everted position. The balloon may be extendable a distance distal of the tube distal end such that a surface of the balloon is contactable with an inner surface of the Fallopian tube. A push wire may have a distal end coupled to a second end of the balloon. The balloon may be movable from the first inverted position to the second everted position by actuation of the push wire. The surface of the balloon may include a plurality of surface features for collection of a tissue sample of the inner surface of the Fallopian tube.

A circular stapling instrument includes an adapter assembly having a tubular body, a shell assembly disposed on a distal portion of the tubular body, and a seal assembly supported on the tubular body. The seal assembly includes an inflatable member disposed proximal of the shell assembly, wherein the inflatable member includes a first diameter when in a deflated condition and a second diameter when in an inflated condition, the second diameter being larger than the first diameter.

A sphincter augmentation device includes a plurality of interlinked bodies and a pair of device ends configured to releasably couple together to secure the bodies in a loop formation sized to fit around an internal anatomical passageway of a patient. The device further includes a plurality of resilient members, with each resilient member extending between an adjacent pair of the bodies. The resilient members are configured to elastically deform to permit the device to transition between a radially contracted state and a radially expanded state. The resilient members bias the device toward the radially contracted state in which the device exerts an inwardly directed force on the anatomical passageway to selectively limit passage of fluids therethrough. The device further includes an expansion limiting member that extends between and is slidably received by an adjacent pair of the bodies, and is configured to limit radial expansion of the device.

A heart treatment device includes a delivery device allowing for simultaneous ablation of the left atrial appendage and delivery of an occluder into the left atrial appendage. The device includes a steerable catheter, an occluder releasably disposed within the catheter, an inflatable balloon coupled to a distal end of the catheter, and an array of electrodes coupled to the balloon. The balloon may be inflated to bring the electrodes into contact with the interior wall of the left atrial appendage. Energy supplied to the electrodes through the catheter ablates the tissue of the left atrial appendage to electrically isolate the left atrial appendage from the heart, and the delivery device deploys the occluder in the left atrial appendage.

The present disclosure, in its various aspects, is directed to expandable guide devices, implementation methods, and related delivery systems. Embodiments according to the present disclosure, including as described herein, may increase the effectiveness and efficiency of endoscopy procedures. In one example, an embodiment includes an expandable guide device, the device configured to slidingly receive an instrument through an instrument lumen of the device. An internal expandable member is disposed within the body and expandable radially from the inward-facing surface of the body, and an external expandable member is disposed about the body and expandable radially from the outward-facing surface. In some embodiments, the external and internal expandable members are balloons and comprise a compliant and a non-compliant material, respectively.

An enclosure provides a prophylactic barrier that may be permeable to gases, hormones, proteins, and peritoneal fluid, but restrains tumor cells within the enclosure so as to inhibit ovarian cancer invasion of adjacent tissue, and increase the speed of diagnosis of ovarian dysplasia, including cancer. The enclosure includes one or more of fiducial markers, heat sensors, and blood flow reflectors, which may be imaged non-invasively in order to detect conditions or pathology affecting the ovary. The enclosure may also include an access port that permits sampling of the enclosure's contents to further aid in detecting or treating conditions or pathology affecting the ovary.

An occlusion clip comprising: (a) a spring; (b) a first runner including a first open top and a first open end adjacent the first open top, the first runner including a first interior camming surface partially delineating a first interior cavity that is open by way of the first open top and the first open end; (c) a second runner including a second open top and a second open end adjacent the second open top, the second runner including a second interior camming surface partially delineating a second interior cavity that is open by way of the second open top and the second open end, where the spring is configured to be coupled to the first runner and the second runner, where the first interior cavity is configured to receive a first portion of the spring, where the second interior cavity is configured to receive a second portion of the spring, where the first camming surface is configured to engage a first cam of the spring, and where the second camming surface is configured to engage a second cam of the spring.