A system for closing a blood vessel includes a housing having a proximal end and a distal end and configured to be held in the hand of a user, an elongate body extending from the distal end of the housing, a distal housing having a proximal end coupled to a distal end of the elongate body and having a cavity including an opening on a side of the distal housing, a lumen passing through the elongate body and terminating at the cavity of the distal housing and configured to couple to a vacuum source, a sensor carried by the distal housing adjacent the cavity and configured for identifying a blood vessel, wherein the lumen is configured to maintain a vacuum within the cavity when a probe having a vessel closure module is inserted within the lumen and the vessel closure module is within the cavity.

A clip device includes an arm portion including a plurality of arms that are biased to an open state; a pressing tube into which a proximal-end portion of the arm portion is accommodated and configured to be able to lock the arm portion in a closed state; an insertion portion connected to a proximal-end opening of the pressing tube at a distal end of the insertion portion; a power transmission member extending through the insertion portion; a link configured to detachably connect a distal-end portion of the power transmission member and a proximal-end portion of the arm portion; a first stopper configured to regulate the distal-end portion of the power transmission member from protruding from a distal-end opening of the pressing tube, and a switching portion configured to switch the clip device between a first state and a second state.

A treatment device includes an indwelling device including a treatment portion, and a tubular member including a proximal-end opening and in which a proximal-end portion of the treatment portion is disposed. The treatment device further includes an actuator including a connector releasably connected to a proximal-end portion of the treatment portion, and a power transmission member connected to the connector for moving the connector. The treatment portion can be fixed with respect to the tubular member when the power transmission member is retracted such that connector pulls the proximal-end portion of the treatment portion in a proximal direction to a predetermined position. The treatment device also includes a regulation portion for regulating a displacement of the connector in a direction separating from a longitudinal axis of the tubular member in the state in which the connector pulls the proximal-end portion towards the predetermined position.

A clipping system includes a pusher element, a holder mounted over an insertion device and clips stacked along a length of the holder. The holder includes a longitudinally channel.

Each clip extends along a curvature defining a tissue-receiving space therewithin and extends about the holder with an exterior surface of the holder holding the clip open with the first and second ends of the clip separated from one another to receive a tissue therein. Each clip is independently deployable from the holder so that, upon release of the clip from the holder, the clip reverts to a closed configuration. In the closed configuration, the first and second ends are moved toward one another to reduce a size of the tissue-receiving space so that tissue is gripped therewithin. The element is mounted over the holder and moved distally along the holder to independently deploy each clips.

A device includes a capsule along with first and second clip arms, proximal ends of which are received within the channel so that the first and second clip arms are movable relative to one another between an open configuration and a closed configuration. A deployment mechanism includes a tension member connected to a proximal end of the first and second arms, a yoke releasably coupled to the tension member and longitudinally movable relative to the capsule to move the first and second arms between the open and closed configurations. The tension member and yoke are configured to separate from one another in response to a predetermined proximal force relative to the tension member. A locking mechanism is coupled to the deployment mechanism and is configured to engage the capsule to lock the one-piece clipping element in the closed configuration, when the yoke is separated from the tension member.

A scalp clip gun, comprising a housing, a magazine, a propulsion mechanism and a locking mechanism. A positioning protrusion is provided at the front end of the housing. A first end of the magazine is provided with a slot, and the slot is cooperatively connected to the positioning protrusion. The propulsion mechanism comprises a trigger, guide rail, a tension spring, a transmission rack, and a driver. The transmission rack is arranged inside the housing and may slide horizontally relative to the housing. The guide rail is arranged in a through-hole of the driver. The driver may move forward relative to the guide rail. The tail end of the guide rail is fixed by means of the locking mechanism and scalp clips are slidingly arranged on the guide rail. The scalp clip gun may quickly and continuously eject the scalp clips.

Methods and tools for folding and/or capturing leaflets of a heart valve are disclosed herein. Prior to or during installing of a prosthetic heart valve, part of a leaflet of an existing valvular structure can be positioned distally and/or folded upon itself. The existing valvular structure may be a native heart valve or a previously-implanted prosthetic heart valve. When the existing valvular structure is at the aortic position, the prosthetic heart valve can be subsequently installed within the existing valvular structure such that the leaflet is maintained in a location that avoids obstructing blood flow to one or more of the coronary arteries.

A disassemblable anastomosis clamp, at least comprising a clamp frame and a first clasping part and a second clasping part connected to the clamp frame. The first clasping part and/or the second clasping part is detachably connected to the clamp frame. At least one clasping part is designed to be detachable from the clamp frame, and thus when removing the anastomosis clamp, the detachable clasping part can be separated from the clamp frame first and then moved away, allowing the anastomosis clamp to be removed safely and conveniently.

A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

A clip applier assembly may include a surgical clip and a clip applier. The surgical clip may include first and second leg members configured to ligate tissue. The first leg member may include a first proximal portion, a first distal portion, a first inner surface, and a first outer surface. The first outer surface may have a convex curvature. The second leg member may include a second proximal portion, a second distal portion, a second inner surface, and a second outer surface. The second leg member may further include an inner portion and an outer portion separated by a channel. The second outer surface may be formed on the outer portion and have a convex curvature. The clip applier may have a first jaw member configured to engage the first outer surface and a second jaw member configured to engage the second outer surface.