A clipping system includes an adapter mounted on an insertion device and a clip including first and second jaws connected via hinges so that the first and second jaws are movable between an insertion configuration and an initial deployed configuration. A deployment member is configured to move the clip distally over and off of the adapter so that, as the clip leaves the adapter, the clip moves from the insertion configuration to the initial deployed configuration. An extending member is releasably coupled to the clip and movably connected to the adapter, and is configured to permit the withdrawal of the adapter away from the clip while the extending member remains coupled to the clip to place the system in a review configuration. The extending member is operable to retract the clip over the adapter, freeing the clip from tissue on which it had been clipped.

An endoscopic clip device for closure of a mucosal defect or transmural perforation in a gastrointestinal wall may include a sleeve and a clip disposed at least partially within and coupled to the sleeve. The clip may be configured for reversibly moving between an open configuration for positioning relative to the wall and a closed configuration for closing the defect or perforation. The clip may include a first clip arm configured for engaging the mucosal and submucosal layers of the wall and including a first needle extending to a distal end of the first clip arm and configured for advancing through the mucosal layer and into at least the submucosal layer, and a second clip arm disposed opposite the first clip arm and configured for engaging the mucosal layer. The device may be configured for advancing through an operative channel of an endoscope or overtube having a tortuous shape.

Surgical clip appliers are provided and includes a channel assembly extending distally from a housing; a clip carrier disposed within said channel assembly and defining a channel and a plurality of windows therein; a plurality of clips slidably disposed within said channel of said clip carrier; a wedge plate reciprocally disposed within said channel assembly, said wedge plate being operatively connected to said handles and including a plurality of apertures formed along a length thereof; and a clip follower slidably disposed within said channel of said clip carrier and disposed proximally of said plurality of clips, said clip follower being configured and adapted for selective engagement with said windows of said clip carrier and said apertures of said wedge plate. The clip follower is configured and adapted to urge said plurality of clips, in a distal direction relative to said clip carrier, upon reciprocal movement of said wedge plate.

A method for producing a surgical instrument is disclosed. The method comprises obtaining a handle, wherein the handle comprises a distal end comprising a shaft interface surface and a first set of magnetic elements. The method further comprises obtaining a shaft, wherein the shaft comprises a proximal end comprising a handle interface surface, a second set of magnetic elements, and a third set of magnetic elements. The method further comprises attaching the shaft to the handle, wherein the shaft interface surface is configured to engage the shaft at the handle interface surface, wherein an attractive magnetic force is configured to pull the handle towards the shaft when the first set of magnetic elements interact with the second magnetic elements, and wherein a repulsive magnetic force is configured to repel the handle from the shaft when the first set of magnetic elements interacts with the third set of magnetic elements.

A cartridge includes an insertion port into which at least a part of an applicator is insertable, a first region for accommodating a clip unit that can be releasably coupled to the applicator, and a second region for removing a coupling member from the applicator.

A ligation device that includes a clip device including an openable arm, a connector connected to the clip device and is able to be released from the connector, a wire connected to the connector and configured to operate the clip device, and a pipe including an opening into which the wire is inserted. An inner diameter of the opening is smaller than a dimension in a diameter direction of the connector in a first state in which the connector and the clip device are connected with each other, and the inner diameter of the opening decreases towards a proximal end side of the pipe and is larger than the dimension of the connector in a second state in which the connector and the clip device are unconnected with each other.

Clip unit with a clip having a plurality of arms that can be opened and closed, a distal end connecting portion that is releasably connected to the clip, a proximal end connecting portion that is connected to a power transmission member; and a rod-shaped portion that longitudinally connects the distal end connecting portion and the proximal end connecting portion. In a cross-section perpendicular to the longitudinal direction, the rod-shaped portion has a first length in a first direction perpendicular to the longitudinal direction that is shorter than a second length in a second direction perpendicular to both the longitudinal direction and the first direction.

A steerable guide catheter includes a tip ring at a distal end and one or more pullwires configured to engage with the tip ring when put in tension, the pullwire(s) thereby subjecting the steerable guide catheter to a curving or turning force. The tip ring includes a saddle and one or more pullwire channels allowing the pullwire to be looped over the saddle such that when the pullwire is placed under tension, it abuts against the saddle of the tip ring. Some embodiments include additional catheters axially aligned within or outside of the steerable guide catheter, and include a keying feature aligning the rotation of the multiple catheters. The keys of the keying feature can be formed of a polyamide with a glass microsphere filler, and can be thermally welded to the catheter.

Disclosed is an atrial appendage clip, including a first clip arm and a second clip arm that are symmetrically arranged; a first cavity and a second cavity are correspondingly provided in the first clip arm and the second clip arm along an axial direction thereof; a first spring and a second spring are correspondingly provided in the first cavity and the second cavity; the first spring is connected with the second clip arm via a first pull wire, and the second spring is connected with the first clip arm via a second pull wire, so as to form a closed loop structure; and as the first spring and the second spring are stretched or compressed, the first clip arm and the second clip arm are opened or closed therebetween.

A delivery system for an interventional device includes an elongate catheter body, a catheter shaft extending within the elongate catheter body and configured to releasably attach to the interventional device, and at least one flexible element attached to a distal portion of the catheter shaft. The at least one flexible element has an expanded configuration in which the at least one flexible element extends beyond an outer circumference of the elongate catheter body and a collapsed configuration in which the at least one flexible element collapses within an inner circumference of the elongate catheter body. The at least one flexible element is configured to act as a tactile stop when pulled proximally against the elongate catheter body and/or to fold over the interventional device to act as a retraction aid.