A guide for drilling a tunnel in a knee joint having intercondylar roof and tibial eminence. The guide can comprise a guide assembly having a positioning member including an inferior end, and a guide arm extending from the positioning member including a trochlear tip; and a drill sleeve having a body attached to the inferior end, an aperture extending along a drilling axis, and a distal end having a patient-specific surface configured to engage an anterior surface of the tibia. A method of producing a tibial tunnel can comprise inserting a trochlear tip of a guide arm between the tibial eminence and the intercondylar roof, adjusting a position of a positioning member connected to the guide arm, engaging a patient-specific tip of a drill sleeve connected to the positioning member with a surface of a tibia, and inserting a drill bit through the drill sleeve to drill a tibial tunnel.

A kit for trans-osseous rotator cuff repair comprising, a handle (101) with a hollow guide (106) and a first connector (104A), a hollow sleeve (103) that passes through the hollow guide (106) in the handle (101), a suture guider (105 and 503) to guide a surgical suture (516) through the hollow sleeve (103), an adaptable hook (107A and 107B) with a narrow slit (118) at one end and a second connector (104B) at opposite end to couple with the first connector (104A), and a pin (901) with first and second apertures (906 and 908) enabling knotless suture of a soft tendon tissue to a bone, wherein the hollow sleeve is adjustable within the hollow guide (106) and a tunnel is created within the bone by creating perpendicularly intersecting a first and a second hole (718 and 706) in that the narrow slit (118) of the adaptable hook (107A and 107B) retrieves the surgical suture (516) from the second hole (706) through the first hole (718) of the tunnel.

A graft fixation device comprising: a graft separator comprising a distal end, a proximal end, a cavity disposed between the distal end and the proximal end, and at least one guide rib disposed radially outboard of the cavity and extending between the distal end and the proximal end; and an interference screw rotatably mountable within the cavity, the interference screw comprising a distal end, a proximal end, and a screw thread disposed intermediate thereof, the screw thread disposed radially outboard of at least a portion of the graft separator and radially inboard of the at least one rib.

Guide for preventing convergence between two or more drilling tunnels and/or drill pins and/or surgical instruments, which move through the drilling tunnels or are placed in them during a multi-ligament repair operation such as ACL and ALL, comprising a body (11) with at least two flat slots (21, 22, 23) extending from the proximal (P) to the distal (D) end of the body; the slots parallel to each other and separated from each other in an inferior superior direction (1-S) of the body, by distance greater than the sum of the radii of the instruments. The body at the proximal end has a profile consisting of two curved parts that protrude into the proximal direction of the body and meet in a central crossroads; and a central axis divides the body into two parts through the central intersection, the curved part of a part of the body protrudes further into the proximal direction than the curved part of the other part of the body.

Fixation device cartridges. At least one example embodiment is a cartridge including: a first tube; a second tube parallel to first tube; a first spacer coupled to the first tube and the second tube such that slots of the first and second tubes face each other; a second spacer coupled to the first tube and the second tube, the first and second spacers defining a suture volume between the slots of the first and second tubes, and the slot of the first tube and the slot of the second tube open into the suture volume; a first bone anchor disposed within the first tube, a first suture line associated with the first bone anchor and extending through the slot; and a second bone anchor disposed within the second tube and coupled to the first suture line.

A guide provides for placing a suture anchor into an outer rim of a glenoid cavity of a patient adjacent an edge of a glenoid labrum. The guide comprises an elongated guide tube having an axial lumen with a distal opening a rim engagement member pivotally attached to the elongated tube adjacent the distal opening. The rim engagement member has a first contact surface and a second contact surface each of which are distal of the guide tube and are separated from each other and disposed on opposite lateral sides of the guide tube whereby to allow placement of the contact member over the glenoid rim, with subsequent angular positioning of the guide tube and passage of an instrument down the lumen to the labrum.

Provided herein are methods and compositions for treating bone osteonecrosis comprising: at least one of a Gelatin tyramine (GT), a gelatin-heparin tyramine (GHT), a gelatin methacryloyl (GelMa), a gelatin acryloyl (GelAC), collagen, or a hydrogel-forming peptide that can be formed ex vivo or in situ for the treatment of bone osteonecrosis; at least one bone growth promoting agent or a macrophage depletion reagent; and optionally one or more pharmaceutically acceptable carriers.

Aspects of the present disclosure relate to systems, devices and methods for performing a surgical step or surgical procedure with visual guidance using an optical head mounted display. Aspects of the present disclosure relate to systems, devices and methods for displaying, placing, fitting, sizing, selecting, aligning, moving a virtual implant on a physical anatomic structure of a patient and, optionally, modifying or changing the displaying, placing, fitting, sizing, selecting, aligning, moving, for example based on kinematic information.

A method and apparatus are provided for transtendinous implantation of a toggle-type bone anchor. Measured from the top surface of the tendon, the entire bone anchor is inserted to a depth of greater than or equal to 20 mm. during a rotator cuff repair on the humeral head. The anchor is pushed by the same bone punch that formed the initial hole to assure proper depth of placement. Further, the apparatus includes a nub portion that, in use, protrudes into the bone hole formed by the bone punch and maintains registration with the bone hole when the bone punch is retracted. An angled distal end on the anchor initiates toggling during insertion into the bone and at least one proximal projecting fin prevents the anchor from backing out of the bone hole while facilitating further rotation of the anchor when a suture is pulled to complete toggling.

In a first embodiment, the present invention includes an instrumentation system for preparing a bone for soft tissue repair, the instrumentation system including a flexible drill pin capable of bending along a curved path; an aimer capable of engaging the flexible pin to bend the flexible pin; and a flexible reamer having a flexible portion along at least a portion of its length, the flexible portion comprising a plurality of laser cuts. In an alternate embodiment, the present invention may also include a method for preparing a bone tunnel in a femur adjacent a knee joint, the method including introducing a flexible drill pin into the knee joint; guiding the flexible drill pin towards a surface of the femur with an instrument introduced into the knee joint; drilling the flexible drill pin into the femur; removing the instrument from the knee joint; introducing a cannulated flexible reamer into the knee joint by placing the flexible pin within the cannulation of the flexible reamer; and reaming the bone tunnel in the femur along the path of the flexible pin.