Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail. In some embodiments, the proximal end may further include a cross-locking feature, which includes a second bone anchor that interlocks with a first bone anchor, for example, for enhanced bone purchase and bony fixation.

A method for computer assisted determination of values of correction parameters for positioning a medical device relative to a target structure or to a reference base. The method includes a numerical procedure that includes the steps of: i) automatic detection of the projection of a cylindrical reference means in a medical image and determination of a minimum of four characteristic landmarks within the projection of the cylindrical reference means; ii) generating a virtual geometric representation of the cylindrical reference means; iii) determining the virtual projection points representing the characteristic landmarks using a virtual geometric representation of the cylindrical reference means; and iv) iterative determination of the position and orientation of the cylindrical reference means by matching the virtual projection points of the virtual geometric representation of the cylindrical reference means with the characteristic landmarks of the projection of the cylindrical reference means.

A fixation plate for securing together adjacent first and second bone sections of a bone with a bone cut extending thereinbetween, the fixation plate comprising: a first fixation portion having a bone interface side superposable against the first bone section and a second fixation portion extending away from the first fixation portion, the second fixation portion including a holding portion shaped to conform to an outer surface of the second bone section when superposed thereto and when the first and second bone sections are at a predetermined angular orientation relative to each other such that a snug fit of the second bone section with the holding portion provides an indication that the first and second bone sections are at the predetermined angular orientation relative to each other.

A template that includes a support structure pivotably mounted to a guide, wherein the guide includes a compass with angle markings, a first guide member extending from the vertex of the compass, a second guide member extending from the vertex of the compass. In another embodiment, a medical imaging system can include a medical imaging machine with a display screen, a support structure affixed to the medical imaging machine, and a guide pivotably mounted to the support structure. A method of aligning medical implants with anatomical structures includes positioning a template over the display screen, and comparing an angle of a medical tool or implant relative to the anatomical structure of the patient to a reference angle on the guide and installing the implant in the patient at the angle indicated by the guide.

A hip/shoulder prosthesis includes: a head component; a metaphyseal component; a diaphyseal nail, and a locking device. The head component includes: a front face and rear face; with a bore, and first and second shaped recesses in the rear face. The metaphyseal component includes: a central transverse aperture at an angle to the metaphyseal component's axis; a first end configured for threaded engagement within the bore of the head component; and a longitudinal hole that begins at the second end, transects the transverse aperture and reaches the first end, to receive the locking device. The diaphyseal nail is inserted in the femoral or humeral canal, and includes: fastening apertures that receive corresponding screws for fastening the diaphyseal nail to the femur or humerus; a portion configured to be received within, and engage, the transverse aperture of the metaphyseal component, and a transverse hole configured to receive the locking device.

A computer assisted surgical system that includes an apparatus for imaging a region of interest of a portion of an anatomy of a subject; a memory containing executable instructions; and a processor programmed using the instructions to receive two or more two-dimensional images of the region of interest taken at different angles from the apparatus and process the two or more two-dimensional images to produce three dimensional information associated with the region of interest.

An instrument for use in entering bone, comprising a blade having at least two prongs and a center cannulation to accommodate a guide wire, wherein the center-cannulated guide wire allows for precise placement of the instrument within the proximal femoral neck of an individual in the treatment of certain orthopedic conditions, including those related to the surgical correction of specific deformities, particular in children and adolescents, namely, proximal femoral deformities.

In one embodiment, an intramedullary nail has a body that includes proximal and distal ends and an inner surface that defines at least one locking hole that extends into an outer surface of the body so as to receive a bone anchor to lock the nail in a medullary canal of a bone. The body has a first biocompatible material that defines at least a portion of the outer surface. The nail has a second material that is different from, and at least partially encapsulated in, the first material. The second material can produce at least one of an electrical current and a magnetic field, and is supported by the nail body such that a position of the at least one bone-anchor locking hole can be detected based on the at least one of the electrical current and the magnetic field.

Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail. In some embodiments, the proximal opening may contain one or more relief cuts.

Provided herein are methods and compositions for treating bone osteonecrosis comprising: at least one of a Gelatin tyramine (GT), a gelatin-heparin tyramine (GHT), a gelatin methacryloyl (GelMa), a gelatin acryloyl (GelAC), collagen, or a hydrogel-forming peptide that can be formed ex vivo or in situ for the treatment of bone osteonecrosis; at least one bone growth promoting agent or a macrophage depletion reagent; and optionally one or more pharmaceutically acceptable carriers.