A reentry catheter for crossing a vascular occlusion includes an elongate flexible tubular body, having a proximal end, a distal end and at least one lumen extending there through. A reentry zone on the tubular body includes at least two and preferably three sets of opposing pairs of axially spaced exit apertures in communication with the lumen. The apertures are rotationally offset from each other and aligned in a spiral pattern around the tubular body. Each aperture may be defined within a radiopaque reinforcing ring embedded within the tubular body. A first set of opposing pairs of reinforcing rings may be separated axially from a second set of opposing pairs of reinforcing rings and may be connected by a flexible hinge section.

Intravascular catheters with fluoroscopically visible indicium of rotational orientation are described. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a tubular side wall defining at least one lumen extending there through. At least first and second opposing pairs of radiopaque rings are embedded in the side wall, spaced axially apart from each other. A first transverse axis extending through the first pair of rings is rotationally offset from a second transverse axis extending through the second pair of rings. The rings may be supported by a subassembly integrated into the wall of the catheter. The subassembly may include a tubular body having a plurality of aperture portions connected by intervening hinge portions. In one implementation, the catheter is a reentry catheter.

A reentry catheter for crossing a vascular occlusion includes an elongate flexible tubular body, having a proximal end, a distal end and at least one lumen extending there through. A reentry zone on the tubular body includes at least two and preferably three sets of opposing pairs of axially spaced exit apertures in communication with the lumen. The apertures are rotationally offset from each other and aligned in a spiral pattern around the tubular body. A method of crossing a chronic total occlusion includes the steps of advancing the reentry catheter across the occlusion via a channel formed in the subintimal space, and advancing a guidewire via a selected exit port into the native lumen distally of the occlusion. The catheter may be removed, leaving the guidewire across the occlusion to guide further interventional devices.

A scoring device includes an elongate shaft, a balloon disposed on a far side of the shaft and inflatable radially of the shaft by a fluid flowing into the balloon, at least one storage tube disposed along an outer surface of the balloon and having a storage lumen defined therein, and an elongate scoring wire storable in the storage tube and made of a harder material than the balloon. The storage tube is fixed to the balloon or the shaft and has an opening portion defined therein that provides fluid communication between outer and inner circumferential surfaces of the storage tube along the storage lumen when the balloon is inflated, and the scoring wire is movable in the storage lumen along a longitudinal axis of the storage tube.

Provided are a treatment method, a separation method, and a filter assembly capable of preventing so-called Blue Toe syndrome which is so-called cholesterol crystal embolism of which a fat-soluble compound such as cholesterol crystals generated during dilation of a stenosed site causes clogging in glomeruli of peripheral capillaries or kidney, acute renal failure, and the like. Cholesterol crystals generated from plaque during use of a balloon catheter are taken out of the body and removed using a centrifugal separation device or a filter, and usable living cells are returned to the body to reduce blood transfusion and reduce cholesterol crystal embolism.

An aspiration system includes a pump and a control system in communication with the pump. The control system includes a microcontroller, an antenna configured to receive a signal, and a pump control board in communication with the microcontroller. The antenna is in communication with the microcontroller. Upon receiving the signal, the pump control board operates the pump to create negative pressure according to the signal.

A medical device designed to be inserted into a lumen of a living body so as to block a flow of fluid in the lumen of the living body. The medical device includes: a long shaft part; an expandable part; and a covering part. The expandable part is an elastically deformable cylindrical body, and the cylindrical body having a proximal part connected to the shaft part. The covering part takes on a cylindrical shape and is flexible and deformable independently of the expandable part, and the cylindrical shape has a proximal part connected to a proximal part of the expandable part or connected to the shaft part located at a proximal side with respect to the expandable part. The covering part defines a space in the radial direction between a distal side end part of the cylindrical shape and the expandable part.

A medical device is disclosed for collecting substances inside a body lumen. The medical device includes an elongated shaft portion; a filter portion that has multiple gaps, that is formed in a net shape, that is deformable to be in an expanded state where the filter portion has a basket shape so as to form a concave portion, and that is deformable from the expanded state to be in a contracted state where an opening end portion of the concave portion is contracted; and a support portion that is formed to include a gap larger than gaps of the filter portion and that includes an interlock portion interlocked with the opening end portion of the filter portion and a support side connection portion connected to the shaft portion.

A device and method for treating a patient with total or near total occlusion is provided. The device can be positioned in a blood vessel at a treatment site. An occlusion at the treatment site is enlarged by a catheter. The catheter can be advanced over a guidewire into the occlusion. One or more of [a] compression or torsion applied to the guidewire or [b] compression or torsion applied to the catheter body expands or creates a path through the occlusion. The expansions or creation of the access path can be by cutting or abrading the occlusion or by a shoe-horn effect.

Vascular treatment devices and methods include a woven structure including a plurality of bulbs that may be self-expanding, a hypotube, for example including interspersed patterns of longitudinally spaced rows of kerfs, and a bonding zone between the woven structure and the hypotube. The woven structure may include patterns of radiopaque filaments measurable under x-ray. Structures may be heat treated to include various shapes at different temperatures. The woven structure may be deployable to implant in a vessel. A catheter may include a hypotube including interspersed patterns of longitudinally spaced rows of kerfs and optionally a balloon. Laser cutting systems may include fluid flow systems.