Disclosed are systems, methods, and devices for percutaneous retrieval of objects, such as endovascular devices, from an internal body space. The present inventions have vascular, non-vascular (gastrointestinal), and surgical (laproscopic) applications. The inventions include a a wire woven distal end that is formed from wires and includes a substantially cylindrical main body section comprising a leading end, a trailing end, and a middle portion extending between the leading end and the trailing end and defining a longitudinal axis of the main body section, and a flare defining a mouth of the wire woven distal end that projects circumferentially from the leading end of the main body section, wherein when at least a portion of the retrieval end is transitioned to a compressed state following capture of an object, the retrieval end exerts an inward force that at least partially collapses or compresses the object.

A device and method for establishing retrograde blood flow during recanalization of a vessel having a targeted blockage. While in a collapsed state an occluding component is introduced distally intravascularly traversing the targeted blockage to its distal side. Then, the occluding component transitions to an expanded state having an enlarged diameter forming a seal with an internal wall of the vessel prohibiting anterograde blood flow beyond the expanded occluding component. Retrograde blood flow is thereby established in a region of the vessel bound at one end by the occluding component and at an opposite end by the targeted blockage by dispensing a flushing fluid into the region of the vessel.

A handle assembly includes a drive wire coupled to an expandable end effector, the wire having a diameter of no more than 3 French and a handle cannula receiving the wire therethrough, rotation of the handle cannula transferring torque to rotate the wire. The assembly also includes a shaft receiving the handle cannula, rotation of the shaft transferring torque to rotate the handle cannula. The assembly further includes an actuation assembly receiving the shaft, the actuation assembly coupled to a sheath sized to receive the wire and end effector therethrough, the actuation assembly moveable between a proximal configuration in which the sheath is moved proximally to expand the end effector and a distal configuration in which the sheath is moved distally to retract the end effector, the actuation assembly including a rotation mechanism transferring torque to the shaft to rotate the shaft.

A device may include a sheath including a lumen, a distal end, and a proximal end. The device may further include an end-effector unit and an elongate member connected to the end-effector unit. The end-effector unit and the sheath may be movable relative to each other to achieve a first state of the end-effector unit and a second state of the end-effector unit. Moreover, the medical device may include a handle having a first handle portion connected to the proximal end of the sheath, a second handle portion connected to the proximal end of the elongate member, and a compliant member longitudinally aligned with the sheath between the first handle portion and the second handle portion. The first and second handle portions may be configured such that relative movement of the first and second handle portions causes the end-effector to move between the first and second states.

A medical instrument, which is capable of holding a wire, includes: a sheath which has a center axis in a longitudinal direction from a distal end toward a proximal end thereof and includes in a distal end surface of the distal end a first contact area capable of being in contact with the wire and a second contact area coming in contact with the wire and provided on a proximal end side beyond the distal end with respect to the first contact area; and a holding portion which is advanceable and retractable in a lumen of the sheath and is retracted into the lumen of the sheath so that the wire is pressed to the first contact area and the second contact area and the holding portion holds the wire.

A medical instrument is that the first holding portion or the second holding portion is capable of moving so that a distance between a distal end of the first holding portion and a distal end of the second holding portion changes from a first dimension which is larger than a diameter of the wire to a second dimension which is smaller than the diameter of the wire and the space is formed by the first holding portion and the second holding portion such that the wire is capable of rotating about a line connecting a first contact point where the first protrusion portion contacts with the wire with a second contact point where the second protrusion portion contacts with the wire.

According to an embodiment of the present disclosure, a retrieval device may include a distally located end effector movable between a contracted state and an expanded state. The end effector may include a plurality of support members each including a passage. The end effector may also include a plurality of movable members. A first movable member may include a first portion extending into a first passage of the support member passages. The retrieval device may also include a proximally located handle assembly including a longitudinal actuator and a twisting actuator coupled to the plurality of movable members. The longitudinal actuator and twisting actuator may be configured to longitudinally move and twist the movable members without longitudinally moving and twisting the support members.

A minimally invasive endovascular device for treating a blocked or obstructed biological lumen, such as a blood vessel fully or partially obstructed by deposits of biological matters in or non-biological matters. Certain embodiments of the present invention comprise two capture members that are configured to be placed on either side of the obstruction and enclose around the obstruction for removal. Embodiments of the present invention also provide methods for implementing an endovascular device according to aspects of the present invention.

A clot retrieval system includes a delivery catheter defining a lumen and having proximal and distal ends. An elongate shaft has proximal and distal ends and is configured for receipt within the delivery catheter. An inverted sleeve has a closed end attached to a distal segment of the elongate shaft and an open end. An outer section of the inverted sleeve that includes the open end is folded over onto an inner section of the inverted sleeve that includes the closed end at a rolling fold. An expansion device is supported on the elongate shaft at an axial location proximally spaced from the closed end and aligned with or distally spaced from the open end. The expansion device is configured for radially expanding the open end of the inverted sleeve.

The present invention relates to a device and a method for capturing a guidewire being progressed along the lumen of a bodily duct and to direct it into a catheter. In one aspect a catheter-based eccentric cone capture structure is used to engage and direct a guidewire oppositely approaching the capture structure.