The invention relates to a clot retrieval and thrombectomy device with adjustable orifice diameter and retrieval length to retrieve embolism from the vascular system, especially pulmonary arteries and venous system, which allows restoring the blood flow to pulmonary vasculature and relieve right heart strain and re-perfusion in occluded veins or arteries with organized thrombus formation. The main objective of the invention is to provide a device that can be used in different vessel dimensions, different types of vessels and situations. The present invention has an adjustable device orifice and retrieval length to overcome the limitations in retrieval of the clots in different vessel dimensions. According to the clot length and volume, the orifice of the braided mesh basket can be adjusted to the vessel diameter. Therefore, the device can be used in every type of vessel having different diameters and in every patient having different conditions.

An endovascular medical system for use with a clot located in a target vessel. The system including a guidewire formed by a core wire. The guidewire extending in a longitudinal direction from a proximal end to an opposite atraumatic clot-circumventing configured distal end; and a lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire being defined transverse to the longitudinal direction of the guidewire. The atraumatic clot-circumventing configured distal end is designed to prevent injury to an inner wall of the target vessel and prohibit insertion of any portion of the guidewire into a perforator vessel.

There is provided herein a non-occlusive blood restricting device for treating a vascular malformation, the blood restricting device consisting of a wire comprising a first section configured to be coiled into a first coil when deployed within the vascular malformation; wherein the first coil comprises a spiral or sequence of loops, the spiral or sequence of loops having a gradually decreasing diameter; and wherein the first coil is configured to line a neck and/or a wall of the vascular malformation so as to at least partially cover an orifice thereof, and a second section configured to be deployed within a blood vessel, adjacent the vascular malformation; wherein the second section is configured to form a second coil, circumferentially lining a wall of the blood vessel.

A thrombectomy catheter system can include a catheter configured for insertion into vasculature of a patient. The system includes a pressure chamber configured to isolate an internal volume from a surrounding environment. The system can include an infusion container including an infusion fluid therein. The pressure chamber can receive the infusion container. A drive unit can pressurize a working fluid in the pressure chamber with the infusion container received in the pressure chamber. In an example, pressurizing of the working fluid correspondingly compresses the infusion container to pressurize the infusion fluid and transfer the infusion fluid to the catheter. In an example, the infusion fluid is isolated from the working fluid by the infusion container when the working fluid is pressurized in the pressure chamber.

A medical device for removing an object in a body cavity, includes a first device including a rotatable drive shaft and a cutter attached to a distal end of the drive shaft and by which the object is cut, a second device movable with respect to the drive shaft along a longitudinal direction of the drive shaft and including a distal-side blood pressure sensor at a distal portion of the second device and a proximal-side blood pressure sensor on a proximal side of the distal-side blood pressure sensor, and a controller configured to acquire a first measurement value from the distal-side blood pressure sensor and a second measurement value from the proximal-side blood pressure sensor, calculate a fractional flow reserve using the first and second measurement values, and control the cutter to cut the object in accordance with the calculated fractional flow reserve.

A medical device for removing an object in a body cavity, includes a rotatable drive shaft, a cutter attached to a distal end of the drive shaft and by which the object is cut, a guide wire including one or more markers, a guide tube disposed at a distal portion of the drive shaft and including a lumen through which the guide wire can pass and a sensor configured to detect the one or more markers, and a controller configured to control an operation state of the cutter to be an operation disabled state in which the cutter cannot operate and an operation enabled state in which the cutter can operate, and to switch between the operation disabled state and the operation enabled state according to the one or more markers detected by the sensor.

An obstruction removal device is described, having one or more engaging members which can engage portions of the clot. The one or more engaging members have a collapsed, delivery state, and an expanded, deployed state which in some embodiments can be locked to maintain its fixed configuration.

An example aspiration system includes an inner member configured to be received within an aspiration catheter lumen and disrupt a thrombus positioned within vasculature of a patient. The inner member includes a distal member at a distal portion of an elongated support member, where the distal member is configured to fit within the aspiration catheter lumen. The distal member defines a larger cross-sectional dimension than the elongated support member, the cross-section being taken in a direction orthogonal to a longitudinal axis of the support member, and is configured to be deployed distally outward from a distal opening of the aspiration catheter lumen to contact and disrupt a thrombus to facilitate the efficiency of a medical aspiration procedure. The distal member may include one or more tapered portions and a surface disruption configured to aid with the thrombus disruption.

The invention provides a system for treating an occlusion within a body lumen. The system may comprise an insulated outer sheath; an elongated conductive tube, wherein the insulated outer sheath is circumferentially mounted around the elongated conductive tube; and an insulated wire having a helically coiled portion at a distal end of the insulated wire. The coiled portion includes an exposed distal tip, and a distal portion of the elongated conductive tube is circumferentially mounted around the distal coiled portion of the insulated wire. When a voltage is applied across the insulated wire and the elongated conductive tube, a current is configured to flow from the exposed distal tip of the insulated wire to the elongated conductive tube to generate a plurality of cavitation bubbles. In an alternate embodiment, an elongated central electrode is used in place of the conductive tube.

A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.