An actuated telescoping system for navigation within a vascular lumen and thrombectomy of a thrombus. The system includes a tubular catheter member having an open distal end defining a catheter lumen, a vacuum source, a rotational drive system, a flexible shaft having a channel coupled to the rotational drive system for rotational movement in response thereto, and an optional guidewire selectively inserted at least partially within the flexible shaft. The flexible shaft is at least partially disposed within the tubular catheter member configured for uncoupled rotational and translational motion therein and to optionally define a corkscrew motion in response to rotational driving force by the drive system that results in formation of hydrodynamic vortices within the catheter lumen. The telescoping system can be capable of reversibly transitioning between navigation and thrombectomy modes by differentially disposing and actuating the components and enable faster, more efficient and simpler removal of thromboembolic material.

A clot retrieval catheter can have an expansile distal tip for flow restriction/arrest and improved aspiration efficiency and a large, distal facing mouth into which clots or other obstructions can be retrieved. The tip can be formed from a distal ring of leaflets or hoops. One or more pull cables can be retracted to actuate and radially expand the expansile distal tip. The clot retrieval catheter can have a catheter shaft with flexibility-adding features proximal of the tip. The catheter shaft can be a multi-lumen configuration with a large catheter lumen for passing auxiliary devices and directing aspiration and one or more guide lumens which can route the pull cables to the leaflets or hoops of the expansile tip. A flexible, low-modulus membrane can be disposed around at least a portion of the expansile tip and catheter shaft.

The invention relates to a thrombectomy device (100), with a wire (105), referred to as a push wire, attached to a woven structure (110) at the distal end of the woven structure, the woven structure surrounding, at the proximal end of the woven structure, an opening (115) having a diameter that varies on the basis of a configuration of the woven structure, and the woven structure having two configurations: an opened-out configuration in which the woven structure is radially spaced apart from the push wire so as to open the opening surrounded by the woven structure and is axially compressed toward the distal end, and a collapsed configuration in which the woven structure is radially near the push wire and axially extended along the push wire.

Provided is a medical device capable of easily changing a position of the device inside a biological lumen and effectively removing a cut object. The medical device for removing the object in the biological lumen has a drive shaft, a cutting portion, a first housing that accommodates the drive shaft to be rotatable, a second housing that is rotatable with respect to the first housing, and a support portion that supports the first housing and the second housing. The second housing and the support portion relatively move along an axis to restrict relative rotation of the first housing and the second housing. The support portion supports the second housing to be rotatable around the axis, and restricts a relative movement and a relative inclination of the second housing and the support portion in a direction intersecting with the axis.

A medical device for removing an object in a body lumen includes a catheter and a drive device. The drive device includes a hub support portion with which a hub portion of the catheter is interlocked. The hub portion has first and second engagement portions interlocked with the hub support portion. The hub support portion includes a rotation blocking portion that is engaged with the first engagement portion to block the hub portion from rotating with respect to the hub support portion, a movement blocking portion that is engaged with the second engagement portion to block movement of the hub portion with respect to the hub support portion in an axial direction, and a releasing portion that releases a state in which a rotation of the hub portion is blocked while maintaining a state in which movement of the hub portion is blocked.

a dilatable balloon catheter, comprising: a guide wire inserted and disposed in the inside of the catheter, an operation portion is fixedly connected to one end of the catheter, a balloon is disposed at the outer side of the catheter remote from the operation portion, the lumen of the catheter and the inner cavity of the balloon are connected by a communication structure provided on the catheter, the guide wire includes a first guide wire and a second guide wire which are separated from each other, the rear end of the first guide wire is connected to insertion-extraction structure in the rear end of the operation portion, the second guide wire is fixed to the inside of the catheter by a fixing process. The guide wire of the dilatable balloon catheter and the liquid injection lumen can share the same lumen, greatly reducing the diameter of the catheter in the present invention, so that the dilatable balloon catheter can be inserted into a narrow duct or lumen that needs to be expanded in human body through an device channel of an endoscope, and realize visualization operation.

Catheter devices, assemblies and related methods for percutaneous crossing of an occlusion in a blood vessel are disclosed. A catheter device can include a central catheter, two side tubes, and a distally-protruding, curved subintimal guidewire. The central catheter can define a central lumen that extends from a proximal end to a distal end of the central catheter. The lumen can be configured to receive a primary guidewire. The central catheter can also define at least one reentry aperture oriented transverse to the central lumen. The first and second side tubes can be coupled with the central catheter, extending along a longitudinal axis thereof, with the first side tube flanking an opposite side of the central catheter relative to the second side tube. The subintimal guidewire can extend from the first side tube, distally beyond the distal end of the central catheter, to the second side tube.

The invention relates to a thrombectomy device (100), comprising a wire (105), referred to as a push wire, attached to a woven structure (110) at the distal end of the woven structure, the woven structure surrounding, at the proximal end of said woven structure, an opening (115) having a diameter that varies on the basis of a configuration of the woven structure, and the woven structure having two configurations: an opened-out configuration in which the woven structure is radially spaced apart from the push wire so as to open the opening surrounded by the woven structure and is axially compressed toward the distal end, and a collapsed configuration in which the woven structure is radially near the push wire and axially extended along the push wire.

A rotational atherectomy device includes a drive shaft, a cutter mechanism coupled to the drive shaft and configured to cut occlusive material from a lesion, and a multi-stage macerator coupled to the drive shaft and configured to macerate cut occlusive material into a fine slurry. Successive stages of the multi-stage macerator macerate the cut occlusive material into successively smaller particles, which are moved proximally through a lumen of a sheath of the device that surrounds the drive shaft proximal to the macerator. The device may include a movable cutter mechanism guard that is passively rotatable between a first position in which it covers the cutter mechanism and a second position in which it exposes the cutter mechanism. One or more features of the device may limit a depth to which the cutter mechanism is able to cut the occlusive material to reduce a likelihood of undesirable tissue dissection.

A thrombosis macerating and aspiration device for macerating and aspirating blood clots and blockages in a blood vessel is disclosed. In some embodiments, the macerating element of the device rotates and creates a partial vacuum to assist in the aspiration of the blood clot of blockage. The macerating element may have a variety of different designs and shapes and in some embodiments, the macerating element is expandable.