In some examples, a capture assembly configured to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system, includes a body configured to receive the material of interest. The body can be configured to axially lengthen and shorten.

An endoscopy instrument is configured to be adjustable between a retracted position and an extended position. The endoscopy instrument includes a snare forming a loop extending from a proximate end to a distal end and a plurality of basket wires. Each of the basket wires includes a proximate end coupled to the proximate end of the snare and a distal end coupled to the distal end of the snare. The snare and the plurality of the basket wires cooperate to form a basket portion configured to contract when the endoscopy instrument is adjusted from the extended position towards the retracted position during entry of the basket portion into a tubular member. The contracting of the basket portion aids in grasping an object in need of retrieval from a patient.

Catheter-delivered endovascular medical devices are described. The devices may include a pull wire attached to a distal body. The distal body may be formed of a distal body outer body comprising a basket comprised of a plurality of cells defined by a plurality of basket strips and a distal body inner body located in the interior of the distal body outer body and comprising a plurality of distal braided mesh openings formed by a plurality of woven linear strands. The distal braided mesh openings may be smaller than the cells when the device is in the relaxed state. Methods of using and making the devices are also described.

A medical device may include a handle assembly having an actuator and a sheath. The sheath may extend between a proximal end and a distal end. The proximal end of the sheath may be coupled with the actuator. The medical device may further include an end-effector moveable relative to the sheath between an extended configuration and a retracted configuration. The end-effector may include a plurality of expandable legs. Each of the plurality of expandable legs may include a plurality of first indicia and a plurality of second indicia. A color of each of the first plurality of indicia may be different than a color of each of the second plurality of indicia.

An endoscope treatment tool includes: a sheath; an operating wire in the sheath; a gripping portion provided at a distal end of the operating wire and having one or more wires; a tip attached to a distal end of the sheath; and a resin member disposed at a position adjacent to the tip on a radially inner or outer side thereof, wherein the tip includes clearance grooves extending toward a proximal end of the tip from a distal end of the tip, passing therethrough from an inner circumferential surface of the tip to an outer circumferential surface of the tip, and having sizes enabling the wires to pass therethrough, and at least proximal-end sides of the grooves overlap with the member in a radial direction of the tip and a distal end of the member is disposed farther on a distal-end side than proximal ends of the grooves are.

A clot removal device for removal of an occlusion from a lumen in a patient's body is provided. The clot removal device has a lumen, an elongated member positioned within the lumen and extending axially from a proximal end to a distal end of the lumen, a handle attached to the proximal end of the lumen, a first expandable member positioned along a length of the elongated member, a second expandable member positioned along the length of the elongated member, wherein the second expandable member is distal to the first expandable member relative to the handle. The handle has at least one actuation mechanism and at least one of the following applies: a) the first expandable member is coupled to the at least one actuation mechanism and is configured to be moveable relative to the second expandable member upon manipulation of the at least one actuation mechanism; b) the first expandable member is configured to mechanically expand or contract by manipulating the at least one actuation mechanism; c) the second expandable member is coupled to the at least one actuation mechanism and is configured to be moveable relative to the first expandable member upon manipulation of the at least one actuation mechanism; or d) the second expandable member is configured to mechanically expand or contract by manipulating the at least one actuation mechanism.

A clot retrieval device comprising an elongate shaft having a proximal end and a distal end and a clot retrieval element at the distal end of the elongate shaft. A proximal end of the elongate shaft configured to retract a first catheter over the elongate shaft. The shaft extension member comprising one or more raised profiles configured to interfere with one or more indentations along the elongate shaft such that the shaft extension member is configured to extend between a first length and an intermediate length. A second catheter is advanced to or adjacent to the distal end of the clot retrieval device shaft to enable enhanced aspiration adjacent to the clot retrieval element.

A retrieval system for thrombus and foreign body removal.

Techniques and devices for removal of clot/material from body passages utilize a main carrying wire, a main elongated sleeve element braided from a plurality of wires to form a proximal tubular section having a proximal opening and a funnel-shaped distal section tapering distally onto a distal end portion of the main carrying wire for rigid attachment thereto, a deformable ring element coupled to the proximal opening of the main elongated braided sleeve element and configured for changing the proximal opening from a normally opened state to an at least partially closed state, and a control wire rigidly coupled to the deformable ring element for manipulating the proximal opening of the main elongated braided sleeve element between its normally opened and at least partially closed states for secure removal of the captured target clot from the blood vessel.

A medical device for removing a material from a hollow anatomical structure is provided. The device may include a shaft member. The device may include an expandable centering element near the distal end of the device. The device may include a macerator element either attached to the shaft or independent and freely moveable from the shaft. Alternatively, the device may include a rotating wire attached to the macerator element. The device may include an aspiration lumen in for removal of material. The device may include a drive shaft attached to a motor and used to rotate the macerator element. The device may be used in combination with a distal occlusion element, which may be either a radially expandable filter or balloon member.