A medical system may include an insertion device having a handle, a shaft coupled to the handle of the insertion device, and a port positioned on the handle of the insertion device. The port may be in fluid communication with a working channel of the shaft. The port may be a female luer port. The medical system may further include a medical device having a control member terminating in an end effector, a handle having a plurality of circumferential slots along the length of the handle, and a plunger moveable along a longitudinal axis of the handle of the medical device between a first position and a second position. In the first position, the end effector may be positioned within the shaft, and in the second position, the end effector may be positioned distally of the shaft.

An apparatus including a basket device including a basket section; and a sheath on the basket device. The basket device and the sheath are configured to longitudinally slide relative to each other. The basket section includes at least two groups of loop petals including a first group having at least two first loop petals and a second group having at least two second loop petals, where the first loop petals have a different size than the second loop petals.

Apparatus and methods employing same for loading and inserting an inverting tube apparatus into a body lumen, such as a blood vessel, including introducers for inverting tube apparatuses. Also described herein are stacked tractor regions and methods of using them for removing larger and/or longer materials from the body lumen. Also described herein are methods and apparatuses for assisting in the manual operation the inverting tube apparatuses described herein, including grips.

Methods for restoring blood flow in occluded blood vessels using an apparatus having a self-expandable distal segment that is pre-formed to assume a superimposed structure in an unconstrained condition but can be made to take on a volume-reduced form making it possible to introduce it with a microcatheter and a push wire arranged at the proximal end, with the distal segment in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments or struts. In a preferred embodiment, the distal segment has a tapering structure at its proximal end where the strings or filaments or struts converge at a connection point.

The designs herein can be for a clot retrieval catheter with a large bore lumen and a distal tip expandable to a diameter larger than that of the guide or sheath through which it is delivered. The designs can have a polymeric flared tip with atraumatic properties and the ability to flexibly expand when ingesting a clot. The tip can have a plurality of axial ribs giving stiffness to certain circumferential regions of the tip for facilitating repeatable collapse when retracted back into the guide or sheath. The tip can also have a metallic support frame within the flared tip for aiding in more gradual compression of clots during aspiration and retrieval with a stentriever. The catheter frame and tip can be sufficiently flexible to navigate highly tortuous areas of the anatomy and recover to maintain the inner diameter of the lumen when displaced in a vessel.

Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh, a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising an expandable mesh is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the mesh is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

Inverting tube apparatuses having an inverting tube (e.g., a knitted tube) that is configured to roll into an inversion support catheter and capture material from within a body lumen such as a blood vessel, in which the knitted tube is configured to prevent locking down onto the outside of the inversion support catheter. The inversion support catheter may include an expandable funnel at the distal end thereof having an interior profile that is adapted to capture and break apart hard material captured by the tractor so that it may be pulled into the inversion support catheter for removal.

Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the removal device. The removal device can have a core assembly that includes a hypotube coupled to a first electrical terminal and a pushwire coupled to a second electrical terminal, the pushwire extending through the hypotube lumen. An insulating layer separates the hypotube and the pushwire, and an interventional element is coupled to a distal end of the pushwire. The interventional element can be disposed adjacent to a thrombus. An electrical signal is delivered to the interventional element to promote adhesion of the thrombus to the interventional element. The electrical signal can optionally be a periodic waveform, and the total energy delivered can be between 0.75-24,000 mJ and the peak current delivered via the electrical signal can be between 0.5-5 mA.

A medical treatment device is disclosed herein. In one example, the medical treatment device includes a core assembly which has a first conduct and a second conductor, the second conductor being formed from a first conductive material. An insulative material can surround the second conductor and define one or more uninsulated portions. A second conductive material can surround the first conductive material along at least a portion of the one or more uninsulated portions and can have a higher electrical conductivity than the first conductive material. The medical treatment device can include an interventional element formed from a third conductive material that electrical couples to the first conductor. A fourth conductive material can be disposed over the third conductive material and have a higher electrical conductivity than the third conductive material.

Apparatuses and methods for retaining a catheter are disclosed. In particular, described herein are apparatuses (e.g., introducer lock apparatuses, devices and systems including them) and methods for securing a catheter relative to an introducer sheath. In particular these apparatuses and method may secure an outer catheter of a mechanical thrombectomy apparatus to prevent the outer catheter from moving proximally when an inner member within the outer catheter is pulled proximally, applying a compression force that would otherwise drive the outer catheter proximally.