Rail tension extraction devices and methods of extracting target(s) inside a patient's body are disclosed. The device includes a base assembly having a handle and an elongate base. The device additionally includes at least one magnet configured to engage a metallic target, and a capture element received in the base assembly and disposed adjacent to the at least one magnet. The capture element is configured to at least partially surround the metallic target engaged by the at least one magnet. The device further includes an outer tube configured to move relative to the elongate base between a locking position in which a distal end of the outer tube is adjacent the capture element and the at least one magnet to secure the metallic target therebetween, and an unlocking position in which the distal end of the outer tube is spaced from the capture element and the at least one magnet.

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

The present subject matter discloses a tissue removal tool for use with an endoscope. The tool comprises a loop formed by a piece of wire and movable between an open position and a closed position, and a transmitting assembly comprising: a handle; and a link having a first end attached to the handle and a second end attached to the loop, the loop portion being movable between the open and closed position by action of the handle. The loop is defined in the open position by a proximal portion and a distal portion. The widest portion of the loop is more proximal to a proximal end of the loop than the mid-point of the length of the loop is.

In some examples, a capture assembly configured to remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system, includes a body configured to receive the material of interest. The body can be configured to axially lengthen and shorten.

An intravascular thrombus retraction device includes: wires that are compressible into a compact cylindrical form within a catheter and are self-expandable into a wire mesh web with at least some parallel wires forming openings in the wire mesh sufficient to allow fluid passage and small enough to filter particles of at least 0.001 mm, a base of the wire mesh web connected to radial ring-shaped structure supporting and maintaining an opening in the base of the wire mesh and forming a thrombus capture volume, and the radial ring-shaped structure being compressible into the catheter and being self-expandable or expandable by struts when free of compressive forces within the catheter to open up into an open, expanded, radial ring-shaped structure which maintains the opening in the opening in the base of the wire mesh.

An apparatus for neurovascular endoluminal intervention, in particular for the treatment of ischemic stroke, is provided. The apparatus comprises a catheter (2) for insertion into the circulatory system (CS) of a patient, in order to aspirate one or several clots (C) present in the circulatory system (CS). A distal outer section (22) of the catheter (2) comprises an unexpanded state, in which the diameter (D2) of the distal outer section (22) is smaller than the diameter (D1) of a proximal outer section (21) of the catheter (2), in order to facilitate navigation of the catheter through the circulatory system, and a radially expanded state, in order to facilitate aspiration of the one or several clots (C) through the catheter (2). Furthermore, a method for applying such an apparatus is provided.

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

The devices and methods described herein relate to jointless construction of complex structures. Such devices have applicability in through-out the body, including clearing of blockages within body lumens, such as the vasculature, by addressing the frictional resistance on the obstruction prior to attempting to translate and/or mobilize the obstruction within the body lumen.

An infusion catheter system may deliver a therapeutic agent to a desired location in the body. The system may include an elongate catheter shaft having a proximal end region, a distal end region, a distal opening, and a lumen extending between the proximal end region and distal opening. The distal end region may include a coiled portion having a preformed coiled configuration including a plurality of helically wound rings. A plurality of apertures may be formed through a sidewall of the coiled portion. A guidewire may be configured to be slidably disposed within the lumen of the catheter shaft. The guidewire may include a proximal end region having a first cross-sectional dimension, an enlarged distal end region having a second cross sectional dimension greater than the first cross-sectional dimension, and an intermediate region disposed between the proximal end region and the distal end region.

There is described a method, a system, and a device for the anchoring of and into a corpus disposed distally in a conduit by engaging a stranded tube with the corpus and unwinding the wound threads of the stranded tube into unwound threads. Engagement includes the use of handling and manipulation shaft to dispose the stranded tube proximally, distally, or in the interior to the corpus. Unwinding, of the stranded tube is achieved by rotating a tube tool against the stranded tube. Unwinding liberates the helically coiled unwound strands in “corkscrew” rotation into the corpus. Proximal retrieval of a corpus is achieved by proximal retrieval of the stranded tube anchoring the corpus. An unwound stranded tube is operable as a fastener, as an electrical lead, and as a support for a device.