A device and a method, which is individual to a patient, treat malignant diseases by using selectively acting tumor-destructive mechanical pulses (TMI). The tumor-destructive pulse shapes are determined using physical cell properties, which are individual to each patient. The device is controlled in such that lethal pulse fields are applied in the tumor area.

A handheld ultrasound device and corresponding methods used for rejuvenating the vulvovaginal area of the user. In general, the handheld ultrasound devices include a device body coupled to an acoustic coupler and a handle. The device body further includes internal components including an ultrasound transducer, an energy delivery element, and circuitry for controlling the ultrasound output. The methods of using the handheld ultrasound device include engaging the tissue in and around the vulvovaginal area with the energy delivery element, applying ultrasound energy to the vulvovaginal tissue from the energy delivery element and through the acoustic coupler, and affecting a measurable parameter associated with vulvovaginal rejuvenation.

A focused extracorporeal shock wave therapy (f-ESWT) device includes a handheld housing, a battery, and a transducer assembly. The battery is located in the handheld housing. The transducer assembly is located in the handheld housing and is operably connected to the battery. The transducer assembly is configured to generate a focused shock wave using electrical energy from the battery.

A focused extracorporeal shock wave therapy (f-ESWT) system includes an f-ESWT device and a plurality of interchangeable standoff structures. The f-ESWT device includes a housing. The f-ESWT device is configured to generate a focused shock wave as a combination of a plurality of individual shock waves. Each standoff structure is configured for removable connection to the housing to receive and to transmit the plurality of individual shock waves. Each standoff structure of the plurality of interchangeable standoff structures includes a rigid exterior shell defining a shell space, and an elastomeric interior at least partially located in the shell space. The plurality of individual shock waves is transmitted through the rigid exterior shell and the elastomeric interior of a selected standoff structure of the plurality of interchangeable standoff structures that is removably connected to the housing.

A method of generating a focused shock wave with a handheld focused extracorporeal shock wave therapy (f-ESWT) device includes driving a plurality of piezoelectric elements to generate a focused shock wave based on a first plurality of time delays when a first standoff structure is removably connected to a handheld housing of the f-ESWT device, and driving the plurality of piezoelectric elements to generate the focused shock wave based on a second plurality of time delays when a second standoff structure is removably connected to the handheld housing of the f-ESWT device, the second plurality of time delays different from the first plurality of time delays, and the second standoff structure different from the first standoff structure.

A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

Embodiments of the present disclosure are directed to systems, devices, and methods of inducing physical effects in tissue, such as dermis, adipose, musculoskeletal, vascular, hepatic tissue, using unfocused or planar, non-cavitating acoustic shock waves. The physical effects include disruption of fibrous extracellular matrix of the targeted tissues. Embodiments of the present disclosure include applying rapid acoustic pulses (e.g., shock waves) to cause a breakdown in the fibrous extracellular matrix to reduce the appearance of cellulite or scars in a treatment area. Such unfocused or planar, non-cavitating acoustic shock waves may induce a tissue reaction, such as reduction of fibrosis, induction of angiogenesis, or lymphangiogenesis.

The present invention provides enhanced ESWL efficacy for therapeutic and operational outcomes. Device behavior and performance data is measured in-situ and analyzed for both intra-procedure and inter-procedure breadth of regard such that both therapy optimization and maintenance optimization engines are provided an accurate and current assessment of ESWL system and device state and performance. This feedback and control provides the ability to compensate in real time for the current patient therapy and offline for future patient therapy for machine/therapy idiosyncrasies and realize continuous calibration of system/devices to the performance required for maximum ESWL patient efficacy.

A system for breaking obstructions in body lumens includes a catheter including an elongated carrier, a balloon about the carrier in sealed relation thereto, the balloon being arranged to receive a fluid therein that inflates the balloon, and an arc generator including at least one electrode within the balloon that forms a mechanical shock wave within the balloon. The system further includes a power source that provides electrical energy to the arc generator.

A tip force monitoring and annunciation means which permits maintaining proper tip pressure during treatment of self-applied acoustic wave treatment for various parts of the user's body by an untrained user. The several embodiments of the disclosure employ designs, materials, and manufacturing methods which are inexpensive and consistent with current manufacturing practices. The functionality, size, cost, simplicity, ease of use, reliability and robustness of the proposed designs are all advantageous.